Xilio Therapeutics (XLO) EBIT Margin (2024 - 2026)
Xilio Therapeutics' EBIT Margin came in at -18.68% for Q2 2026, up 159.03 percentage points from -177.71% a year earlier and up 92.90 percentage points from the prior quarter.
Xilio Therapeutics (XLO) EBIT Margin (2024 - 2026) Analysis & Trends
Over the trailing twelve months to Jun 30, 2026, Xilio Therapeutics reported EBIT Margin of -48.94%, up 328.42 percentage points year-over-year; for FY2025, it came in at -95.92%, up 859.03 percentage points from FY2024.
- Going back by year, EBIT Margin was -954.95% in FY2024.
- The five-year range for quarterly EBIT Margin is -790.55% (Q4 2024) to -10.12% (Q3 2025).
- Year-over-year, EBIT Margin has increased for five consecutive quarters, with an average year-over-year change of +462.52 percentage points over the last five quarters.
- Business Quant data shows XLO's EBIT Margin at -111.57% (Q1 2026), -86.48% (Q4 2025) and -10.12% (Q3 2025) in the three quarters before Q2 2026.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | EBIT Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Eli Lilly | 1,136.97 Bn | 1,105.55 Bn | 19.71 Bn | 51.16% |
| 2 | Johnson & Johnson | 619.72 Bn | 538.25 Bn | 17.26 Bn | 28.21% |
| 3 | AbbVie | 503.40 Bn | 476.52 Bn | 12.70 Bn | 37.86% |
| 4 | Merck | 370.15 Bn | 324.53 Bn | 12.21 Bn | -3.52% |
| 5 | Novartis Ag | 298.64 Bn | 262.63 Bn | 11.24 Bn | 32.97% |
| 6 | Astrazeneca | 261.07 Bn | 234.76 Bn | 12.86 Bn | 20.57% |
| 7 | Amgen | 237.00 Bn | 192.40 Bn | 7.24 Bn | 34.95% |
| 8 | Gilead Sciences | 191.24 Bn | 165.43 Bn | 6.22 Bn | -133.21% |
| 9 | Pfizer | 170.31 Bn | 116.96 Bn | 10.94 Bn | 28.37% |
| 10 | Xilio Therapeutics | 162.81 Mn | -364.86 Mn | - | -18.68% |
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | -18.68% |
| Mar 31, 2026 | -111.57% |
| Dec 31, 2025 | -86.48% |
| Sep 30, 2025 | -10.12% |
| Jun 30, 2025 | -177.71% |
| Mar 31, 2025 | -472.73% |
| Dec 31, 2024 | -790.55% |
| Sep 30, 2024 | -652.32% |
| Jun 30, 2024 | -623.84% |
Xilio Therapeutics EBIT Margin API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=ebit-margin&ticker=XLO&period=max&api_key=YOUR_API_KEY
import requests
url = "https://data.businessquant.com/historic"
params = {"slug": "ebit-margin", "ticker": "XLO", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()
const res = await fetch("https://data.businessquant.com/historic?slug=ebit-margin&ticker=XLO&period=max&api_key=YOUR_API_KEY");
const data = await res.json();