Xilio Therapeutics (XLO) EBIT Margin (2024 - 2026)
Xilio Therapeutics' EBIT Margin came in at -18.68% for Q2 2026, up 159.03 percentage points from -177.71% a year earlier and up 92.90 percentage points from the prior quarter.
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Analysis
Xilio Therapeutics (XLO) EBIT Margin (2024 - 2026) Analysis & Trends
Over the trailing twelve months to Jun 30, 2026, Xilio Therapeutics reported EBIT Margin of -48.94%, up 328.42 percentage points year-over-year; for FY2025, it came in at -95.92%, up 859.03 percentage points from FY2024.
- Going back by year, EBIT Margin was -954.95% in FY2024.
- The five-year range for quarterly EBIT Margin is -790.55% (Q4 2024) to -10.12% (Q3 2025).
- Year-over-year, EBIT Margin has increased for five consecutive quarters, with an average year-over-year change of +462.52 percentage points over the last five quarters.
- Business Quant data shows XLO's EBIT Margin at -111.57% (Q1 2026), -86.48% (Q4 2025) and -10.12% (Q3 2025) in the three quarters before Q2 2026.
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | EBIT Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Eli Lilly | 1,348.13 Bn | 1,321.74 Bn | 20.46 Bn | 34.46% |
| 2 | Johnson & Johnson | 675.90 Bn | 595.76 Bn | 17.30 Bn | 24.35% |
| 3 | AbbVie | 519.45 Bn | 487.50 Bn | 13.12 Bn | 36.01% |
| 4 | Merck | 364.95 Bn | 327.95 Bn | 13.19 Bn | 30.74% |
| 5 | Novartis Ag | 311.58 Bn | 285.16 Bn | - | - |
| 6 | Astrazeneca | 289.34 Bn | 262.94 Bn | 13.26 Bn | 29.12% |
| 7 | Amgen | 251.64 Bn | 203.30 Bn | 7.58 Bn | 35.79% |
| 8 | Gilead Sciences | 212.05 Bn | 187.07 Bn | 6.73 Bn | 41.71% |
| 9 | Pfizer | 167.35 Bn | 115.00 Bn | 12.56 Bn | 32.98% |
| 10 | Xilio Therapeutics | 167.94 Mn | -378.15 Mn | - | -117.68% |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Sep 30, 2026 | -117.68% |
| Jun 30, 2026 | -18.68% |
| Mar 31, 2026 | -111.57% |
| Dec 31, 2025 | -86.48% |
| Sep 30, 2025 | -10.12% |
| Jun 30, 2025 | -177.71% |
| Mar 31, 2025 | -472.73% |
| Dec 31, 2024 | -790.55% |
| Sep 30, 2024 | -652.32% |
| Jun 30, 2024 | -623.84% |
API Access
Xilio Therapeutics EBIT Margin API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=ebit-margin&ticker=XLO&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "ebit-margin", "ticker": "XLO", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=ebit-margin&ticker=XLO&period=max&api_key=YOUR_API_KEY");
const data = await res.json();