Growth Metrics

Vertex Pharmaceuticals (VRTX) EBIT Margin (2009 - 2026)

Vertex Pharmaceuticals' quarterly EBIT Margin came in at 38.1% in Q1 2026, up 1536.0% year-on-year from 2.33% in Q1 2025, and up 0.8% quarter-over-quarter from 37.8% in Q4 2025.

Vertex Pharmaceuticals has reported EBIT Margin for 18 years, with the latest figure at 38.1% in Q1 2026.

  • For the quarter ending Q1 2026, EBIT Margin rose 1536.0% year-over-year to 38.1%; the trailing twelve-month figure through Mar 2026 stood at 38.31% (up 4500.0% YoY), and the FY2025 full-year result was 34.77%, up 3689.0% from the prior year.
  • EBIT Margin for Q1 2026 stood at 38.1%, up from 37.8% in the prior quarter.
  • The five-year high for EBIT Margin was 50.37% in Q2 2022, with the low at 132.85% in Q2 2024.
  • Average EBIT Margin over 5 years is 29.95%, with a median of 39.26% recorded in 2023.
  • Year-over-year, EBIT Margin slumped 17402 bps in 2024 and soared 17168 bps in 2025.
  • Tracing VRTX's EBIT Margin over 5 years: stood at 44.88% in 2022, then dropped by 13 bps to 39.26% in 2023, then dropped by 10 bps to 35.23% in 2024, then advanced by 7 bps to 37.8% in 2025, then rose by 1 bps to 38.1% in 2026.
  • The last three EBIT Margin figures came in at 38.1% (Q1 2026), 37.8% (Q4 2025), and 38.56% (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBIT Margin (Qtr)
1 Quantum Biopharma 961,148.99 Bn 961,148.98 Bn - -
2 Alterity Therapeutics 744,933.29 Bn 744,933.26 Bn - -
3 Legend Biotech 2,540.00 Bn 2,539.71 Bn 242.10 Mn -6.43%
4 Nanobiotix 2,199.85 Bn 2,199.78 Bn - -
5 Akari Therapeutics 1,635.88 Bn 1,635.88 Bn - -
6 Vertex Pharmaceuticals 111.32 Bn 104.07 Bn 2.59 Bn 38.10%
7 Evaxion A 62.56 Bn 62.54 Bn - -
8 Regeneron Pharmaceuticals 62.55 Bn 53.79 Bn 3.31 Bn 17.83%
9 Alnylam Pharmaceuticals 39.57 Bn 36.56 Bn 959.66 Mn 23.02%
10 Revolution Medicines 32.39 Bn 32.39 Bn - -

Historic Data

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DateValue
Mar 31, 2026 38.10%
Dec 31, 2025 37.80%
Sep 30, 2025 38.56%
Jun 30, 2025 38.83%
Mar 31, 2025 22.75%
Dec 31, 2024 35.23%
Sep 30, 2024 40.27%
Jun 30, 2024 -132.85%
Mar 31, 2024 42.35%
Dec 31, 2023 39.26%
Sep 30, 2023 41.80%
Jun 30, 2023 41.17%
Mar 31, 2023 32.80%
Dec 31, 2022 44.88%
Sep 30, 2022 48.27%
Jun 30, 2022 50.37%
Mar 31, 2022 49.63%
Dec 31, 2021 42.35%
Sep 30, 2021 53.15%
Jun 30, 2021 -2.11%
Mar 31, 2021 51.49%
Dec 31, 2020 45.82%
Sep 30, 2020 43.70%
Jun 30, 2020 47.10%
Mar 31, 2020 47.54%
Dec 31, 2019 353.96%
Sep 30, 2019 10.46%
Jun 30, 2019 28.68%
Mar 31, 2019 32.25%
Dec 31, 2018 14.68%
Sep 30, 2018 26.21%
Jun 30, 2018 22.98%
Mar 31, 2018 20.12%
Dec 31, 2017 19.30%
Sep 30, 2017 -56.39%
Jun 30, 2017 9.69%
Mar 31, 2017 37.89%
Dec 31, 2016 8.64%
Sep 30, 2016 -4.57%
Jun 30, 2016 0.79%
Mar 31, 2016 -3.60%
Dec 31, 2015 -13.21%
Sep 30, 2015 -23.15%
Jun 30, 2015 -103.06%
Mar 31, 2015 -131.41%
Dec 31, 2014 -106.27%
Sep 30, 2014 -103.72%
Jun 30, 2014 -147.60%
Mar 31, 2014 -182.39%
Dec 31, 2013 -7.98%
Sep 30, 2013 -55.73%
Jun 30, 2013 -18.46%
Mar 31, 2013 -130.69%
Dec 31, 2012 -23.20%
Sep 30, 2012 -0.32%
Jun 30, 2012 -2.57%
Mar 31, 2012 24.42%
Dec 31, 2011 39.75%
Sep 30, 2011 51.41%
Mar 31, 2011 -217.07%
Dec 31, 2010 -254.31%
Sep 30, 2010 -838.78%
Jun 30, 2010 -536.25%
Mar 31, 2010 -714.62%
Dec 31, 2009 -432.94%
Sep 30, 2009 -593.95%
Jun 30, 2009 -824.42%
Mar 31, 2009 -675.14%