Xilio Therapeutics (XLO) EBIT (2020 - 2026)

Xilio Therapeutics' (XLO) quarterly EBIT came in at -$14.1 million in Q1 2026, down 1.88% year-on-year from -$14.4 million in Q1 2025, and down 19.23% quarter-over-quarter from -$11.8 million in Q4 2025.

Xilio Therapeutics (XLO) EBIT (2020 - 2026) Analysis & Trends

Xilio Therapeutics has disclosed EBIT across 7 years of filings, most recently posting -$14.1 million for Q1 2026.

  • EBIT for Q1 2026 came in at -$14.1 million, down 1.88% year-over-year; the trailing twelve-month figure through Mar 2026 was -$42.2 million (up 25.82% YoY), and the FY2025 annual result was -$42.0 million, up 30.7% from the prior year.
  • EBIT came in at -$14.1 million for Q1 2026 at Xilio Therapeutics, down from -$11.8 million in the prior quarter.
  • In the past five years, EBIT ranged from a high of -$1.9 million in Q3 2025 to a low of -$24.6 million in Q2 2022.
  • The 5-year median for EBIT is -$17.4 million (2023), against an average of -$16.8 million.
  • Across the five-year window, EBIT decreased 28.47% in 2022 and surged 86.93% in 2025, its largest moves.
  • Xilio Therapeutics' EBIT stood at -$23.2 million in 2022, then grew by 21.74% to -$18.1 million in 2023, then rose by 24.83% to -$13.6 million in 2024, then rose by 13.16% to -$11.8 million in 2025, then slipped by 19.23% to -$14.1 million in 2026.
  • The last three EBIT figures came in at -$14.1 million (Q1 2026), -$11.8 million (Q4 2025), and -$1.9 million (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBIT (Qtr)
1 Alterity Therapeutics 925,601.88 Bn 925,601.85 Bn - -
2 Belite Bio 58,560.00 Bn 58,560.00 Bn - -32.68 Mn
3 Quantum Biopharma 17,284.41 Bn 17,284.40 Bn - -2.97 Mn
4 Legend Biotech 2,809.00 Bn 2,808.71 Bn 242.10 Mn -19.70 Mn
5 Evaxion A 1,334.43 Bn 1,334.42 Bn - -3.82 Mn
6 Akari Therapeutics 1,312.27 Bn 1,312.26 Bn - -15.76 Mn
7 Psyence Biomedical 212.16 Bn 212.16 Bn - -1.51 Mn
8 Vertex Pharmaceuticals 114.83 Bn 107.58 Bn 2.59 Bn 1.14 Bn
9 Abivax 91.96 Bn 91.96 Bn - -65.83 Mn
10 Xilio Therapeutics 144.35 Mn -5.95 Mn - -14.11 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 -14.11 Mn
Dec 31, 2025 -11.84 Mn
Sep 30, 2025 -1.93 Mn
Jun 30, 2025 -14.37 Mn
Mar 31, 2025 -13.85 Mn
Dec 31, 2024 -13.63 Mn
Sep 30, 2024 -14.76 Mn
Jun 30, 2024 -14.70 Mn
Mar 31, 2024 -17.49 Mn
Dec 31, 2023 -18.13 Mn
Sep 30, 2023 -17.36 Mn
Jun 30, 2023 -20.12 Mn
Mar 31, 2023 -23.53 Mn
Dec 31, 2022 -23.17 Mn
Sep 30, 2022 -20.21 Mn
Jun 30, 2022 -24.55 Mn
Mar 31, 2022 -21.22 Mn
Dec 31, 2021 -19.56 Mn
Sep 30, 2021 -15.96 Mn
Jun 30, 2021 -23.01 Mn