Xilio Therapeutics (XLO) Change in Cash (2020 - 2026)

Xilio Therapeutics' (XLO) quarterly Change in Cash came in at $12.8 million in Q1 2026, down 62.09% year-on-year from $33.8 million in Q1 2025, and down 62.08% quarter-over-quarter from $33.8 million in Q4 2025.

Xilio Therapeutics (XLO) Change in Cash (2020 - 2026) Analysis & Trends

Xilio Therapeutics has disclosed Change in Cash across 7 years of filings, most recently posting $12.8 million for Q1 2026.

  • Change in Cash for Q1 2026 came in at $12.8 million, down 62.09% year-over-year; the trailing twelve-month figure through Mar 2026 was $61.3 million (up 13.24% YoY), and the FY2025 annual result was $82.3 million, up 662.98% from the prior year.
  • Change in Cash came in at $12.8 million for Q1 2026 at Xilio Therapeutics, down from $33.8 million in the prior quarter.
  • In the past five years, Change in Cash ranged from a high of $40.0 million in Q2 2024 to a low of -$27.1 million in Q1 2023.
  • The 5-year median for Change in Cash is -$15.1 million (2023), against an average of -$2.8 million.
  • Across the five-year window, Change in Cash sank 119.08% in 2022 and soared 666.57% in 2025, its largest moves.
  • Xilio Therapeutics' Change in Cash stood at -$18.8 million in 2022, then increased by 19.69% to -$15.1 million in 2023, then soared by 60.42% to -$6.0 million in 2024, then jumped by 666.57% to $33.8 million in 2025, then tumbled by 62.08% to $12.8 million in 2026.
  • The last three Change in Cash figures came in at $12.8 million (Q1 2026), $33.8 million (Q4 2025), and -$17.8 million (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Change in Cash (Qtr)
1 Alterity Therapeutics 925,601.88 Bn 925,601.85 Bn - -
2 Belite Bio 58,560.00 Bn 58,560.00 Bn - -
3 Quantum Biopharma 17,284.41 Bn 17,284.40 Bn - 2.44 Mn
4 Legend Biotech 2,809.00 Bn 2,808.71 Bn 242.10 Mn 623.00 Mn
5 Evaxion A 1,334.43 Bn 1,334.42 Bn - -
6 Akari Therapeutics 1,312.27 Bn 1,312.26 Bn - -2.44 Mn
7 Psyence Biomedical 212.16 Bn 212.16 Bn - -
8 Vertex Pharmaceuticals 114.83 Bn 107.58 Bn 2.59 Bn 417.10 Mn
9 Abivax 91.96 Bn 91.96 Bn - -45.97 Mn
10 Xilio Therapeutics 144.35 Mn -5.95 Mn - 12.81 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 12.81 Mn
Dec 31, 2025 33.77 Mn
Sep 30, 2025 -17.78 Mn
Jun 30, 2025 32.48 Mn
Mar 31, 2025 33.79 Mn
Dec 31, 2024 -5.96 Mn
Sep 30, 2024 -13.68 Mn
Jun 30, 2024 39.98 Mn
Mar 31, 2024 -9.55 Mn
Dec 31, 2023 -15.06 Mn
Sep 30, 2023 -15.61 Mn
Jun 30, 2023 -17.88 Mn
Mar 31, 2023 -27.11 Mn
Dec 31, 2022 -18.75 Mn
Sep 30, 2022 -20.26 Mn
Jun 30, 2022 -17.55 Mn
Mar 31, 2022 -21.09 Mn
Dec 31, 2021 98.29 Mn
Sep 30, 2021 -20.53 Mn
Jun 30, 2021 -20.92 Mn