X4 Pharmaceuticals (XFOR) Gross Margin (2024 - 2025)

X4 Pharmaceuticals (XFOR) posted Gross Margin of 85.83% for Q4 2025, up 7.13% on a QoQ basis from 80.11% in Q3 2025, and up 689.0% year-over-year from 10.88% in Q4 2024.

X4 Pharmaceuticals (XFOR) Gross Margin (2024 - 2025) Analysis & Trends

X4 Pharmaceuticals' Gross Margin history runs 2 years deep, the most recent figure standing at 85.83% for Q4 2025.

  • Quarterly Gross Margin rose 689.0% year-over-year to 85.83% in Q4 2025, while the trailing twelve-month figure through Dec 2025 was 83.6% (up 1477.0% YoY) and the FY2025 annual result came in at 83.6%, up 1477.0% from the prior year.
  • Gross Margin was 85.83% for Q4 2025 at X4 Pharmaceuticals, up from 80.11% in the prior quarter.
  • Across five years, Gross Margin topped out at 85.83% in Q4 2025 and bottomed at 52.4% in Q2 2024.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Gross Margin (Qtr)
1 Oculis Holding AG 66,621.14 Bn 66,620.85 Bn - -
2 Nanobiotix 1,915.18 Bn 1,915.11 Bn - -
3 Akari Therapeutics 1,014.18 Bn 1,014.18 Bn - -
4 BeOne Medicines 471.27 Bn 466.48 Bn 1.35 Bn 88.95%
5 Vertex Pharmaceuticals 121.81 Bn 114.57 Bn 2.59 Bn 86.85%
6 Regeneron Pharmaceuticals 69.58 Bn 60.82 Bn 3.31 Bn 91.79%
7 Belite Bio 62.72 Bn 62.72 Bn - -
8 Argenx Se 55.51 Bn 50.33 Bn 1.41 Bn 90.68%
9 Revolution Medicines 37.35 Bn 37.35 Bn - -
10 X4 Pharmaceuticals 167.90 Mn -49.15 Mn 2.20 Mn 85.83%

Historic Data

Download Data
DateValue
Dec 31, 2025 85.83%
Sep 30, 2025 80.11%
Jun 30, 2025 83.48%
Mar 31, 2025 83.63%
Dec 31, 2024 78.94%
Sep 30, 2024 59.46%
Jun 30, 2024 52.40%