Xeris Biopharma Holdings (XERS) Gross Margin (2020 - 2026)

Xeris Biopharma Holdings (XERS) posted Gross Margin of 87.28% for Q1 2026, little changed on a QoQ basis from 87.24% in Q4 2025, and up 180.0% year-over-year from 31.17% in Q1 2025.

Xeris Biopharma Holdings (XERS) Gross Margin (2020 - 2026) Analysis & Trends

Xeris Biopharma Holdings' Gross Margin history runs 7 years deep, the most recent figure standing at 87.28% for Q1 2026.

  • Quarterly Gross Margin rose 180.0% year-over-year to 87.28% in Q1 2026, while the trailing twelve-month figure through Mar 2026 was 85.89% (up 368.0% YoY) and the FY2025 annual result came in at 85.41%, up 355.0% from the prior year.
  • Gross Margin was 87.28% for Q1 2026 at Xeris Biopharma Holdings, roughly flat from 87.24% in the prior quarter.
  • Across five years, Gross Margin topped out at 87.28% in Q1 2026 and bottomed at 71.58% in Q1 2022.
  • A 5-year average of 82.52% and a median of 83.37% in 2025 frame the typical range for Gross Margin.
  • Annual changes were most pronounced in 2022 — Gross Margin surged 1898 bps — and 2024, when it slumped 808 bps.
  • Xeris Biopharma Holdings' Gross Margin stood at 81.02% in 2022, then gained by 2 bps to 82.95% in 2023, then climbed by 2 bps to 84.23% in 2024, then increased by 4 bps to 87.24% in 2025, then rose by 0 bps to 87.28% in 2026.
  • Business Quant data shows XERS's Gross Margin at 87.28% in Q1 2026, 87.24% in Q4 2025, and 85.22% in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Gross Margin (Qtr)
1 Haleon 87.22 Bn 85.35 Bn - -
2 Teva Pharmaceutical Industries 39.60 Bn 35.87 Bn 1.97 Bn 49.52%
3 Zoetis 31.46 Bn 29.52 Bn 1.62 Bn 71.66%
4 Takeda Pharmaceutical 26.49 Bn 22.44 Bn 4.39 Bn 62.93%
5 United Therapeutics 23.03 Bn 20.88 Bn 648.10 Mn 82.93%
6 Universe Pharmaceuticals 23.03 Bn -10.56 Bn - -
7 Viatris 20.90 Bn 19.09 Bn 1.16 Bn 32.97%
8 Neurocrine Biosciences 17.50 Bn 16.19 Bn 800.70 Mn 98.31%
9 Elanco Animal Health 12.33 Bn 11.91 Bn 785.00 Mn 57.26%
10 Xeris Biopharma Holdings 1.43 Bn 1.32 Bn 72.55 Mn 87.28%

Historic Data

Download Data
DateValue
Mar 31, 2026 87.28%
Dec 31, 2025 87.24%
Sep 30, 2025 85.22%
Jun 30, 2025 83.37%
Mar 31, 2025 85.48%
Dec 31, 2024 84.23%
Sep 30, 2024 74.95%
Jun 30, 2024 83.79%
Mar 31, 2024 85.31%
Dec 31, 2023 82.95%
Sep 30, 2023 83.03%
Jun 30, 2023 80.12%
Mar 31, 2023 83.98%
Dec 31, 2022 81.02%
Sep 30, 2022 82.30%
Jun 30, 2022 80.99%
Mar 31, 2022 71.58%
Dec 31, 2021 77.19%
Sep 30, 2021 70.89%
Jun 30, 2021 62.01%