Xeris Biopharma Holdings (XERS) Gross Margin (2020 - 2026)
Xeris Biopharma Holdings (XERS) posted Gross Margin of 87.28% for Q1 2026, little changed on a QoQ basis from 87.24% in Q4 2025, and up 180.0% year-over-year from 31.17% in Q1 2025.
Xeris Biopharma Holdings (XERS) Gross Margin (2020 - 2026) Analysis & Trends
Xeris Biopharma Holdings' Gross Margin history runs 7 years deep, the most recent figure standing at 87.28% for Q1 2026.
- Quarterly Gross Margin rose 180.0% year-over-year to 87.28% in Q1 2026, while the trailing twelve-month figure through Mar 2026 was 85.89% (up 368.0% YoY) and the FY2025 annual result came in at 85.41%, up 355.0% from the prior year.
- Gross Margin was 87.28% for Q1 2026 at Xeris Biopharma Holdings, roughly flat from 87.24% in the prior quarter.
- Across five years, Gross Margin topped out at 87.28% in Q1 2026 and bottomed at 71.58% in Q1 2022.
- A 5-year average of 82.52% and a median of 83.37% in 2025 frame the typical range for Gross Margin.
- Annual changes were most pronounced in 2022 — Gross Margin surged 1898 bps — and 2024, when it slumped 808 bps.
- Xeris Biopharma Holdings' Gross Margin stood at 81.02% in 2022, then gained by 2 bps to 82.95% in 2023, then climbed by 2 bps to 84.23% in 2024, then increased by 4 bps to 87.24% in 2025, then rose by 0 bps to 87.28% in 2026.
- Business Quant data shows XERS's Gross Margin at 87.28% in Q1 2026, 87.24% in Q4 2025, and 85.22% in Q3 2025.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Gross Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Haleon | 87.22 Bn | 85.35 Bn | - | - |
| 2 | Teva Pharmaceutical Industries | 39.60 Bn | 35.87 Bn | 1.97 Bn | 49.52% |
| 3 | Zoetis | 31.46 Bn | 29.52 Bn | 1.62 Bn | 71.66% |
| 4 | Takeda Pharmaceutical | 26.49 Bn | 22.44 Bn | 4.39 Bn | 62.93% |
| 5 | United Therapeutics | 23.03 Bn | 20.88 Bn | 648.10 Mn | 82.93% |
| 6 | Universe Pharmaceuticals | 23.03 Bn | -10.56 Bn | - | - |
| 7 | Viatris | 20.90 Bn | 19.09 Bn | 1.16 Bn | 32.97% |
| 8 | Neurocrine Biosciences | 17.50 Bn | 16.19 Bn | 800.70 Mn | 98.31% |
| 9 | Elanco Animal Health | 12.33 Bn | 11.91 Bn | 785.00 Mn | 57.26% |
| 10 | Xeris Biopharma Holdings | 1.43 Bn | 1.32 Bn | 72.55 Mn | 87.28% |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | 87.28% |
| Dec 31, 2025 | 87.24% |
| Sep 30, 2025 | 85.22% |
| Jun 30, 2025 | 83.37% |
| Mar 31, 2025 | 85.48% |
| Dec 31, 2024 | 84.23% |
| Sep 30, 2024 | 74.95% |
| Jun 30, 2024 | 83.79% |
| Mar 31, 2024 | 85.31% |
| Dec 31, 2023 | 82.95% |
| Sep 30, 2023 | 83.03% |
| Jun 30, 2023 | 80.12% |
| Mar 31, 2023 | 83.98% |
| Dec 31, 2022 | 81.02% |
| Sep 30, 2022 | 82.30% |
| Jun 30, 2022 | 80.99% |
| Mar 31, 2022 | 71.58% |
| Dec 31, 2021 | 77.19% |
| Sep 30, 2021 | 70.89% |
| Jun 30, 2021 | 62.01% |