Xenon Pharmaceuticals (XENE) Return on Sales (2013 - 2025)

Xenon Pharmaceuticals' (XENE) quarterly Return on Sales came in at 0.47% in Q4 2025, down 15.98% on a QoQ basis from 0.41% in Q3 2025.

Xenon Pharmaceuticals (XENE) Return on Sales (2013 - 2025) Analysis & Trends

Xenon Pharmaceuticals (XENE) has 11 years of Return on Sales data on file, last reported at 0.47% in Q4 2025.

  • On a quarterly basis, Return on Sales changed N/A year-over-year to 0.47% in Q4 2025; TTM through Dec 2025 was 0.47%, a N/A change from a year earlier, with the FY2025 full-year figure at 0.47%, changed N/A from the prior year.
  • Return on Sales for Q4 2025 stood at 0.47%, down from 0.41% in the prior quarter.
  • Over the last five years, Return on Sales for XENE reached as high as 0.02% in Q3 2021 and fell as low as 15.08% in Q2 2024.
  • Historically, Return on Sales has averaged 1.64% across 4 years, with a median of 0.25% in 2022.
  • Across the five-year window, Return on Sales tumbled 280 bps in 2022 and surged 1471 bps in 2025, its largest moves.
  • Year by year, Return on Sales stood at 0.07% in 2021, then tumbled by 80 bps to 0.13% in 2022, then sank by 11244 bps to 15.08% in 2024, then soared by 97 bps to 0.47% in 2025.
  • Per Business Quant data, the three most recent Return on Sales figures were 0.47% in Q4 2025, 0.41% in Q3 2025, and 0.37% in Q2 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) ROS (Qtr)
1 Oculis Holding AG 68,785.72 Bn 68,785.72 Bn - -
2 Nanobiotix 1,895.57 Bn 1,895.51 Bn - -
3 BeOne Medicines 471.35 Bn 466.56 Bn 1.35 Bn 0.00%
4 NuCana 279.75 Bn 279.75 Bn - -
5 Vertex Pharmaceuticals 120.24 Bn 113.00 Bn 2.59 Bn 0.00%
6 Regeneron Pharmaceuticals 67.80 Bn 59.04 Bn 3.31 Bn 0.00%
7 Belite Bio 62.51 Bn 62.51 Bn - -
8 Argenx Se 57.38 Bn 57.38 Bn 1.41 Bn 0.00%
9 Revolution Medicines 37.78 Bn 37.78 Bn - -
10 Xenon Pharmaceuticals 5.71 Bn 5.71 Bn - -

Historic Data

Download Data
DateValue
Dec 31, 2025 -0.47%
Sep 30, 2025 -0.41%
Jun 30, 2025 -0.37%
Mar 31, 2025 -0.09%
Jun 30, 2024 -15.08%
Mar 31, 2024 -2.82%
Dec 31, 2022 -0.13%
Sep 30, 2022 -2.81%
Jun 30, 2022 -0.58%
Mar 31, 2022 -0.02%
Dec 31, 2021 -0.07%
Sep 30, 2021 -0.02%
Jun 30, 2021 -0.10%
Mar 31, 2021 -0.04%
Dec 31, 2020 -0.02%
Sep 30, 2020 -0.01%
Jun 30, 2020 0.00%
Mar 31, 2020 -0.01%
Dec 31, 2019 0.00%
Sep 30, 2019 -0.03%