Xenon Pharmaceuticals XENE Institutional Ownership

NASDAQ XENE

$59.58 -0.83 (-1.37%)

As of: Sep 4, 2026 · 11:51 AM EDT

Institutions by Trading Activity

315 Institutions

Increased 176 55.9%

Unchanged 53 16.8%

Reduced 86 27.3%

Ownership Statistics

13F · as of 30 Jun, 2026

Institutional Ownership

101.71%

▼-17.77 pp QoQ

Shares Held by Institutions

101.31Mn

of 99.61Mn outstanding

▲+9.67% QoQ

Shares Outstanding

99.61Mn

-1.70Mn held outside 13F filers

Institutional Investors

315

filed 13F for Jun 2026

▲+27 vs prior quarter

Net Shares Added (QoQ)

+8.93Mn

accumulated since last quarter

Value of Holdings

$6.12Bn

reported market value

Shares Owned by Institutions

Shares held % of outstanding

Latest —

Average ownership —

Peak ownership —

Shares Purchased/Sold by Institutions

Accumulated Distributed

Latest quarter —

Net over range —

Accumulating quarters —

Ownership Summary

Quarter ending 30 Jun, 2026

Xenon Pharmaceuticals Inc. (NASDAQ:XENE) has 315 institutional investors with active 13F positions as of June 2026.

Their combined ownership stood at 101.7% of outstanding shares in June 2026, down from 119.5% in March 2026.
Their total shares held in XENE increased 9.67% from the prior quarter, while the number of investors in Xenon Pharmaceuticals increased 54.41% year over year.
Of these 315 holders, 176 added to their stakes in Xenon Pharmaceuticals, 86 trimmed positions, and 53 made no changes.
In total, institutional investors held 101.31Mn shares in Xenon Pharmaceuticals as of June 2026, up by 8.93Mn shares quarter on quarter, and up 17.88Mn shares year over year.
FMR LLC is the top holder of Xenon Pharmaceuticals as of June 30, 2026, with 9.65Mn shares representing 9.69% of outstanding stock.
Top purchasers of XENE stock for the quarter ending June 2026 included Jupiter Topco LLC (4.19Mn), PRICE T ROWE ASSOCIATES INC /MD/ (1.92Mn), BlackRock, Inc. (1.88Mn), T. Rowe Price Investment Management, Inc. (1.22Mn), TWO SIGMA INVESTMENTS, LP (1.04Mn).
The biggest sellers of Xenon Pharmaceuticals for the quarter ending June 2026 included WELLINGTON MANAGEMENT GROUP LLP (3.4Mn), CITADEL ADVISORS LLC (1.25Mn), FMR LLC (1.17Mn), JENNISON ASSOCIATES LLC (1.11Mn), Alyeska Investment Group, L.P. (601.78K).
According to Business Quant data, leading holders of XENE for June 2026 are FMR LLC (9.65Mn), BlackRock, Inc. (7.52Mn), Avoro Capital Advisors LLC (5.78Mn), Polar Capital Holdings Plc (4.57Mn), DRIEHAUS CAPITAL MANAGEMENT LLC (4.42Mn), Jupiter Topco LLC (4.19Mn), PRICE T ROWE ASSOCIATES INC /MD/ (3.25Mn), Jpmorgan Chase & Co (2.62Mn), Capital International Investors (2.36Mn), T. Rowe Price Investment Management, Inc. (2.17Mn).

Form 13F Holdings

315 Institutional Holders

Report period 30 Jun, 2026

Total shares held 101.31Mn

Of outstanding 101.71%

#	Institution	CIK	Shares Held	% of Outstanding	Change (QoQ)	Change (%)	Value (USD)
1	FMR LLC	0000315066	9,647,998	9.69%	▼1,170,493	-10.82%	$582.35Mn
2	BlackRock, Inc.	0002012383	7,522,482	7.55%	▲1,882,364	+33.37%	$454.06Mn
3	Avoro Capital Advisors LLC	0001633313	5,777,777	5.80%	0	0.00%	$348.75Mn
4	Polar Capital Holdings Plc	0001837309	4,570,556	4.59%	▲165,244	+3.75%	$275.88Mn
5	DRIEHAUS CAPITAL MANAGEMENT LLC	0000938206	4,418,557	4.44%	▼73,096	-1.63%	$266.70Mn
6	Jupiter Topco LLC	0002146052	4,186,519	4.20%	▲4,186,519	0.00%	$252.67Mn
7	PRICE T ROWE ASSOCIATES INC /MD/	0000080255	3,248,219	3.26%	▲1,918,628	+144.30%	$196.06K
8	Jpmorgan Chase & Co	0000019617	2,617,360	2.63%	▲693,750	+36.07%	$157.38Mn
9	Capital International Investors	0001562230	2,361,639	2.37%	▼313,088	-11.71%	$142.55Mn
10	T. Rowe Price Investment Management, Inc.	0001897612	2,168,581	2.18%	▲1,216,626	+127.80%	$130.90K
11	State Street Corp	0000093751	1,969,629	1.98%	▲249,096	+14.48%	$118.89Mn
12	TWO SIGMA INVESTMENTS, LP	0001179392	1,642,848	1.65%	▲1,036,763	+171.06%	$99.16Mn
13	DEERFIELD MANAGEMENT COMPANY, L.P.	0001009258	1,615,696	1.62%	0	0.00%	$97.52Mn
14	Affinity Asset Advisors, LLC	0001773195	1,595,000	1.60%	▼80,000	-4.78%	$96.27Mn
15	ALLIANCEBERNSTEIN L.P.	0001109448	1,562,276	1.57%	▲158,979	+11.33%	$90.85Mn
16	WESTFIELD CAPITAL MANAGEMENT CO LP	0001177719	1,507,294	1.51%	▲105,811	+7.55%	$90.98Mn
17	Franklin Resources Inc	0000038777	1,437,712	1.44%	▲157,135	+12.27%	$86.78Mn
18	WELLINGTON MANAGEMENT GROUP LLP	0000902219	1,425,492	1.43%	▼3,404,149	-70.48%	$86.04Mn
19	CITADEL ADVISORS LLC	0001423053	1,401,242	1.41%	▼1,251,748	-47.18%	$84.58Mn
20	GEODE CAPITAL MANAGEMENT, LLC	0001214717	1,370,114	1.38%	▲277,182	+25.36%	$82.69Mn

Showing 1 to 20 of 315 holders