Xenon Pharmaceuticals Inc. (NASDAQ:XENE) is held by 239 institutional investors per 13F filings through December 2025.
| Owner Name | Date | Shares Held | Change (QoQ) | Change (%) | Value (USD) |
|---|---|---|---|---|---|
| FMR LLC | 31 Mar, 2026 | 10,818,491 | 1,898,241 | 21.28% | $629,095,252.00 |
| Janus Henderson Group Plc | 31 Mar, 2026 | 8,351,964 | 4,267,930 | 104.50% | $485,716,906.00 |
| Avoro Capital Advisors LLC | 31 Mar, 2026 | 5,777,777 | -5,071,111 | -46.74% | $335,977,733.00 |
| BlackRock, Inc. | 31 Mar, 2026 | 5,640,118 | 539,834 | 10.58% | $327,972,862.00 |
| WELLINGTON MANAGEMENT GROUP LLP | 31 Mar, 2026 | 4,829,641 | 64,862 | 1.36% | $280,843,625.00 |
| DRIEHAUS CAPITAL MANAGEMENT LLC | 31 Mar, 2026 | 4,491,653 | -47,038 | -1.04% | $261,189,622.00 |
| Polar Capital Holdings Plc | 31 Mar, 2026 | 4,405,312 | 1,939,618 | 78.66% | $256,168,893.00 |
| Capital International Investors | 31 Mar, 2026 | 2,674,727 | -740,232 | -21.68% | $155,535,375.00 |
| CITADEL ADVISORS LLC | 31 Mar, 2026 | 2,652,990 | 1,331,777 | 100.80% | $154,271,368.00 |
| Jpmorgan Chase & Co | 31 Mar, 2026 | 1,923,610 | 429,578 | 28.75% | $106,856,563.00 |
| State Street Corp | 31 Mar, 2026 | 1,720,533 | 227,983 | 15.27% | $100,048,994.00 |
| Affinity Asset Advisors, LLC | 31 Mar, 2026 | 1,675,000 | 425,000 | 34.00% | $97,401,250.00 |
| DEERFIELD MANAGEMENT COMPANY, L.P. | 31 Mar, 2026 | 1,615,696 | 1,073,676 | 198.09% | $93,952,722.00 |
| Holocene Advisors, LP | 31 Mar, 2026 | 1,518,686 | 236,605 | 18.45% | $88,311,591.00 |
| ALLIANCEBERNSTEIN L.P. | 31 Mar, 2026 | 1,403,297 | -190,517 | -11.95% | $62,895,772.00 |
| WESTFIELD CAPITAL MANAGEMENT CO LP | 31 Mar, 2026 | 1,401,483 | 174,712 | 14.24% | $81,496,236.00 |
| Caligan Partners LP | 31 Mar, 2026 | 1,393,027 | 843,362 | 153.43% | $81,004,520.00 |
| BNP Paribas Asset Management Holding S.A. | 31 Mar, 2026 | 1,342,028 | 281,807 | 26.58% | $78,038,929.00 |
| BRAIDWELL LP | 31 Mar, 2026 | 1,338,452 | -486,624 | -26.66% | $77,830,984.00 |
| PRICE T ROWE ASSOCIATES INC /MD/ | 31 Mar, 2026 | 1,329,591 | 1,329,591 | 0.00% | $77,317.00 |