Xenon Pharmaceuticals (XENE) Return on Capital Employed (2014 - 2026)

Xenon Pharmaceuticals (XENE) reported Return on Capital Employed of 42.53% for Q1 2026, down 287.0% year-over-year from 22.75% in Q1 2025, and up 34.02% quarter-over-quarter from 64.47% in Q4 2025.

Xenon Pharmaceuticals (XENE) Return on Capital Employed (2014 - 2026) Analysis & Trends

Xenon Pharmaceuticals (XENE) has 13 years of Return on Capital Employed data on file, last reported at 42.53% in Q1 2026.

  • Return on Capital Employed for Q1 2026 came in at 42.53%, down 287.0% year-over-year; the trailing twelve-month figure through Mar 2026 was 42.53% (down 287.0% YoY), and the FY2025 annual result was 55.36%, down 2234.0% from the prior year.
  • Return on Capital Employed climbed to 42.53% in Q1 2026 per XENE's latest filing, from 64.47% in the prior quarter.
  • Over five years, Return on Capital Employed peaked at 4.06% in Q1 2022 and troughed at 64.47% in Q4 2025.
  • A 5-year average of 29.98% and a median of 27.61% in 2023 frame the typical range for Return on Capital Employed.
  • The sharpest annual moves came in 2022 and 2025: Return on Capital Employed jumped 1018 bps in 2022, then sank 2872 bps in 2025.
  • A 5-year view of Return on Capital Employed shows it stood at 17.4% in 2022, then tumbled by 56 bps to 27.07% in 2023, then sank by 32 bps to 35.74% in 2024, then sank by 80 bps to 64.47% in 2025, then jumped by 34 bps to 42.53% in 2026.
  • Business Quant data shows XENE's Return on Capital Employed at 42.53% in Q1 2026, 64.47% in Q4 2025, and 56.54% in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) ROCE (Qtr)
1 Alterity Therapeutics 925,601.88 Bn 925,601.85 Bn - -
2 Belite Bio 58,560.00 Bn 58,560.00 Bn - -
3 Quantum Biopharma 17,284.41 Bn 17,284.40 Bn - 450.31%
4 Legend Biotech 2,809.00 Bn 2,808.71 Bn 242.10 Mn 51.73%
5 Evaxion A 1,334.43 Bn 1,334.42 Bn - -
6 Akari Therapeutics 1,312.27 Bn 1,312.26 Bn - -107.40%
7 Psyence Biomedical 212.16 Bn 212.16 Bn - -
8 Vertex Pharmaceuticals 114.83 Bn 107.58 Bn 2.59 Bn 21.10%
9 Abivax 91.96 Bn 91.96 Bn - -50.43%
10 Xenon Pharmaceuticals 4.61 Bn 4.61 Bn - -42.53%

Historic Data

Download Data
DateValue
Mar 31, 2026 -42.53%
Dec 31, 2025 -64.47%
Sep 30, 2025 -56.54%
Jun 30, 2025 -47.08%
Mar 31, 2025 -39.66%
Dec 31, 2024 -35.74%
Sep 30, 2024 -30.78%
Jun 30, 2024 -27.29%
Mar 31, 2024 -24.36%
Dec 31, 2023 -27.07%
Sep 30, 2023 -31.18%
Jun 30, 2023 -27.61%
Mar 31, 2023 -22.51%
Dec 31, 2022 -17.40%
Sep 30, 2022 -6.82%
Jun 30, 2022 -4.55%
Mar 31, 2022 -4.06%
Dec 31, 2021 -5.27%
Sep 30, 2021 -17.00%
Jun 30, 2021 -14.10%