Xenon Pharmaceuticals (XENE) Return on Capital Employed (2014 - 2026)

Xenon Pharmaceuticals' (XENE) quarterly Return on Capital Employed came in at 42.53% in Q1 2026, down 287.0% year-on-year from 22.75% in Q1 2025, and up 34.02% on a QoQ basis from 64.47% in Q4 2025.

Xenon Pharmaceuticals (XENE) Return on Capital Employed (2014 - 2026) Analysis & Trends

Xenon Pharmaceuticals (XENE) has 13 years of Return on Capital Employed data on file, last reported at 42.53% in Q1 2026.

  • On a quarterly basis, Return on Capital Employed fell 287.0% year-over-year to 42.53% in Q1 2026; TTM through Mar 2026 was 42.53%, a 287.0% decrease from a year earlier, with the FY2025 full-year figure at 55.36%, down 2234.0% from the prior year.
  • Return on Capital Employed for Q1 2026 stood at 42.53%, up from 64.47% in the prior quarter.
  • Over the last five years, Return on Capital Employed for XENE reached as high as 13.17% in Q2 2022 and fell as low as 64.47% in Q4 2025.
  • Historically, Return on Capital Employed has averaged 31.53% across 5 years, with a median of 27.61% in 2023.
  • Across the five-year window, Return on Capital Employed jumped 1188 bps in 2022 and tumbled 2872 bps in 2025, its largest moves.
  • Year by year, Return on Capital Employed stood at 17.4% in 2022, then plunged by 56 bps to 27.07% in 2023, then slumped by 32 bps to 35.74% in 2024, then slumped by 80 bps to 64.47% in 2025, then jumped by 34 bps to 42.53% in 2026.
  • Per Business Quant data, the three most recent Return on Capital Employed figures were 42.53% in Q1 2026, 64.47% in Q4 2025, and 56.54% in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) ROCE (Qtr)
1 Oculis Holding AG 68,785.72 Bn 68,785.72 Bn - -31.80%
2 Nanobiotix 1,895.57 Bn 1,895.51 Bn - -
3 BeOne Medicines 471.35 Bn 466.56 Bn 1.35 Bn 10.46%
4 NuCana 279.75 Bn 279.75 Bn - -68.47%
5 Vertex Pharmaceuticals 120.24 Bn 113.00 Bn 2.59 Bn 21.10%
6 Regeneron Pharmaceuticals 67.80 Bn 59.04 Bn 3.31 Bn 10.19%
7 Belite Bio 62.51 Bn 62.51 Bn - -
8 Argenx Se 57.38 Bn 57.38 Bn 1.41 Bn -
9 Revolution Medicines 37.78 Bn 37.78 Bn - -68.84%
10 Xenon Pharmaceuticals 5.71 Bn 5.71 Bn - -42.53%

Historic Data

Download Data
DateValue
Mar 31, 2026 -42.53%
Dec 31, 2025 -64.47%
Sep 30, 2025 -56.54%
Jun 30, 2025 -47.08%
Mar 31, 2025 -39.66%
Dec 31, 2024 -35.74%
Sep 30, 2024 -30.78%
Jun 30, 2024 -27.29%
Mar 31, 2024 -24.36%
Dec 31, 2023 -27.07%
Sep 30, 2023 -31.18%
Jun 30, 2023 -27.61%
Mar 31, 2023 -22.51%
Dec 31, 2022 -17.40%
Sep 30, 2022 -14.26%
Jun 30, 2022 -13.17%
Mar 31, 2022 -14.42%
Dec 31, 2021 -19.56%
Sep 30, 2021 -26.13%
Jun 30, 2021 -22.85%