Upstream Bio (UPB) Free Cash Flow (2023 - 2026)
Upstream Bio's Free Cash Flow was -$35.62 million in Q2 2026, compared with -$39.24 million a year earlier.
Powered by 
Analysis
Upstream Bio (UPB) Free Cash Flow (2023 - 2026) Analysis & Trends
On a trailing twelve-month basis, Upstream Bio's Free Cash Flow was -$136.46 million through Jun 30, 2026; for FY2025, it came in at -$133.44 million.
- In earlier years, Free Cash Flow was -$59.68 million in FY2024 and -$38.07 million in FY2023.
- Quarterly Free Cash Flow has moved between -$47.85 million (Q1 2026) and -$8.04 million (Q2 2024) over five years.
- Per Business Quant data, UPB's Free Cash Flow in the three quarters before Q2 2026 was -$47.85 million (Q1 2026), -$30.69 million (Q4 2025) and -$22.3 million (Q3 2025).
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | FCF (Qtr) |
|---|---|---|---|---|---|
| 1 | Eli Lilly | 1,137.66 Bn | 1,106.24 Bn | 19.71 Bn | 7.76 Bn |
| 2 | Johnson & Johnson | 636.13 Bn | 556.00 Bn | 17.30 Bn | 6.36 Bn |
| 3 | AbbVie | 505.28 Bn | 478.39 Bn | 12.70 Bn | 3.11 Bn |
| 4 | Merck | 358.10 Bn | 312.48 Bn | 12.21 Bn | 4.48 Bn |
| 5 | Novartis Ag | 292.59 Bn | 256.58 Bn | 11.24 Bn | 5.56 Bn |
| 6 | Astrazeneca | 265.81 Bn | 239.50 Bn | 12.86 Bn | 1.01 Bn |
| 7 | Amgen | 237.53 Bn | 192.93 Bn | 7.24 Bn | 3.49 Bn |
| 8 | Gilead Sciences | 194.67 Bn | 168.86 Bn | 6.22 Bn | 3.43 Bn |
| 9 | Pfizer | 171.17 Bn | 117.82 Bn | 10.94 Bn | 302.00 Mn |
| 10 | Upstream Bio | 149.93 Mn | -1.12 Bn | -3.29 Mn | -35.62 Mn |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | -35.62 Mn |
| Mar 31, 2026 | -47.85 Mn |
| Dec 31, 2025 | -30.69 Mn |
| Sep 30, 2025 | -22.30 Mn |
| Jun 30, 2025 | -39.24 Mn |
| Mar 31, 2025 | -41.17 Mn |
| Dec 31, 2024 | -19.80 Mn |
| Sep 30, 2024 | -13.96 Mn |
| Jun 30, 2024 | -8.04 Mn |
| Mar 31, 2024 | -17.56 Mn |
| Dec 31, 2023 | -16.11 Mn |
API Access
Upstream Bio Free Cash Flow API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=free-cash-flow&ticker=UPB&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "free-cash-flow", "ticker": "UPB", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=free-cash-flow&ticker=UPB&period=max&api_key=YOUR_API_KEY");
const data = await res.json();