Tyra Biosciences (TYRA) Return on Equity [ROE] (2021 - 2026)
Tyra Biosciences (TYRA) recorded Return on Equity [ROE] of -40.09% in Q2 2026, down 6.26 percentage points from -33.83% a year earlier but up 0.46 percentage points from the prior quarter.
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Analysis
Tyra Biosciences (TYRA) Return on Equity [ROE] (2021 - 2026) Analysis & Trends
For FY2025, Tyra Biosciences reported Return on Equity [ROE] of -39.83%, down 8.23 percentage points from FY2024.
- Annual Return on Equity [ROE] has declined for four straight years, with a four-year change of -21.59 percentage points (FY2021 to FY2025).
- Across earlier years, Return on Equity [ROE] came in at -31.60% in FY2024 (-1.67 pp), -29.92% in FY2023 (-10.17 pp), -19.76% in FY2022 (-1.52 pp) and -18.24% in FY2021.
- Quarterly Return on Equity [ROE] has ranged from -44.45% in Q4 2025 to -8.59% in Q4 2021 over the past five years.
- On a year-over-year basis, Return on Equity [ROE] has declined for six consecutive quarters, with an average year-over-year change of -7.35 percentage points over the last eight quarters.
- Peak year-over-year performance for Return on Equity [ROE] in the last five years was a gain of 7.91 percentage points in Q4 2024, against a drop of 19.93 percentage points in Q4 2025 at the low end.
- Per Business Quant, the preceding three quarters came in at -40.54% (Q1 2026), -44.45% (Q4 2025) and -38.34% (Q3 2025).
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | ROE (Qtr) |
|---|---|---|---|---|---|
| 1 | Johnson & Johnson | 638.12 Bn | 556.64 Bn | 17.26 Bn | 25.32% |
| 2 | AbbVie | 462.60 Bn | 435.75 Bn | 12.70 Bn | - |
| 3 | Merck | 358.70 Bn | 313.13 Bn | 12.21 Bn | 7.21% |
| 4 | Novartis Ag | 272.16 Bn | 228.03 Bn | 11.24 Bn | 84.40% |
| 5 | Astrazeneca | 250.36 Bn | 223.92 Bn | 12.86 Bn | 21.39% |
| 6 | Amgen | 227.87 Bn | 183.27 Bn | 7.24 Bn | 83.75% |
| 7 | Gilead Sciences | 184.97 Bn | 159.08 Bn | 6.22 Bn | -18.38% |
| 8 | Pfizer | 162.61 Bn | 109.56 Bn | 10.94 Bn | 4.97% |
| 9 | Vertex Pharmaceuticals | 132.45 Bn | 104.46 Bn | 2.84 Bn | 22.24% |
| 10 | Tyra Biosciences | 1.30 Bn | 1.30 Bn | - | -40.09% |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | -40.09% |
| Mar 31, 2026 | -40.54% |
| Dec 31, 2025 | -44.45% |
| Sep 30, 2025 | -38.34% |
| Jun 30, 2025 | -33.83% |
| Mar 31, 2025 | -28.93% |
| Dec 31, 2024 | -24.52% |
| Sep 30, 2024 | -22.68% |
| Jun 30, 2024 | -21.12% |
| Mar 31, 2024 | -25.40% |
| Dec 31, 2023 | -32.42% |
| Sep 30, 2023 | -25.68% |
| Jun 30, 2023 | -20.74% |
| Mar 31, 2023 | -20.66% |
| Dec 31, 2022 | -21.03% |
| Sep 30, 2022 | -19.15% |
| Jun 30, 2022 | -16.30% |
| Mar 31, 2022 | -12.44% |
| Dec 31, 2021 | -8.59% |
| Sep 30, 2021 | -13.95% |
API Access
Tyra Biosciences Return on Equity [ROE] API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=return-on-equity-%5Broe%5D&ticker=TYRA&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "return-on-equity-[roe]", "ticker": "TYRA", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=return-on-equity-%5Broe%5D&ticker=TYRA&period=max&api_key=YOUR_API_KEY");
const data = await res.json();