Tyra Biosciences (TYRA) Operating Income (2020 - 2026)
Tyra Biosciences (TYRA) posted Operating Income of -$42.0 million for Q1 2026, down 15.01% on a QoQ basis from -$36.5 million in Q4 2025, and down 31.86% year-over-year from -$61.6 million in Q1 2025.
Tyra Biosciences (TYRA) Operating Income (2020 - 2026) Analysis & Trends
Tyra Biosciences' Operating Income history runs 7 years deep, the most recent figure standing at -$42.0 million for Q1 2026.
- Quarterly Operating Income fell 31.86% year-over-year to -$42.0 million in Q1 2026, while the trailing twelve-month figure through Mar 2026 was -$142.9 million (down 25.66% YoY) and the FY2025 annual result came in at -$132.8 million, down 27.44% from the prior year.
- Operating Income was -$42.0 million for Q1 2026 at Tyra Biosciences, down from -$36.5 million in the prior quarter.
- Across five years, Operating Income topped out at -$13.6 million in Q3 2022 and bottomed at -$42.0 million in Q1 2026.
- A 5-year average of -$24.6 million and a median of -$24.0 million in 2023 frame the typical range for Operating Income.
- Annual changes were most pronounced in 2022 — Operating Income tumbled 252.27% — and 2023, when it advanced 3.37%.
- Tyra Biosciences' Operating Income stood at -$15.0 million in 2022, then slumped by 70.69% to -$25.6 million in 2023, then dropped by 16.03% to -$29.7 million in 2024, then retreated by 22.77% to -$36.5 million in 2025, then declined by 15.01% to -$42.0 million in 2026.
- Business Quant data shows TYRA's Operating Income at -$42.0 million in Q1 2026, -$36.5 million in Q4 2025, and -$32.9 million in Q3 2025.
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Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Op. Inc (Qtr) |
|---|---|---|---|---|---|
| 1 | Oculis Holding AG | 68,785.72 Bn | 68,785.72 Bn | - | -27.75 Mn |
| 2 | Nanobiotix | 1,895.57 Bn | 1,895.51 Bn | - | - |
| 3 | BeOne Medicines | 471.35 Bn | 466.56 Bn | 1.35 Bn | 249.90 Mn |
| 4 | NuCana | 279.75 Bn | 279.75 Bn | - | -3.72 Mn |
| 5 | Vertex Pharmaceuticals | 120.24 Bn | 113.00 Bn | 2.59 Bn | 1.14 Bn |
| 6 | Regeneron Pharmaceuticals | 67.80 Bn | 59.04 Bn | 3.31 Bn | 642.90 Mn |
| 7 | Belite Bio | 62.51 Bn | 62.51 Bn | - | -32.68 Mn |
| 8 | Argenx Se | 57.38 Bn | 57.38 Bn | 1.41 Bn | 493.00 Mn |
| 9 | Revolution Medicines | 37.78 Bn | 37.78 Bn | - | -445.22 Mn |
| 10 | Tyra Biosciences | 1.90 Bn | 1.90 Bn | - | -42.00 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -42.00 Mn |
| Dec 31, 2025 | -36.52 Mn |
| Sep 30, 2025 | -32.94 Mn |
| Jun 30, 2025 | -31.45 Mn |
| Mar 31, 2025 | -31.85 Mn |
| Dec 31, 2024 | -29.74 Mn |
| Sep 30, 2024 | -28.60 Mn |
| Jun 30, 2024 | -23.53 Mn |
| Mar 31, 2024 | -22.32 Mn |
| Dec 31, 2023 | -25.63 Mn |
| Sep 30, 2023 | -23.96 Mn |
| Jun 30, 2023 | -16.01 Mn |
| Mar 31, 2023 | -14.33 Mn |
| Dec 31, 2022 | -15.02 Mn |
| Sep 30, 2022 | -13.65 Mn |
| Jun 30, 2022 | -15.43 Mn |
| Mar 31, 2022 | -14.83 Mn |
| Dec 31, 2021 | -9.93 Mn |
| Sep 30, 2021 | -6.64 Mn |
| Jun 30, 2021 | -5.51 Mn |