Tyra Biosciences (TYRA) EBT (2020 - 2026)

Tyra Biosciences (TYRA) posted EBT of -$363.7 million for Q1 2026, down 968.75% on a QoQ basis from -$34.0 million in Q4 2025, and down 774.12% year-over-year from $54.0 million in Q1 2025.

Tyra Biosciences (TYRA) EBT (2020 - 2026) Analysis & Trends

Tyra Biosciences' EBT history runs 7 years deep, the most recent figure standing at -$363.7 million for Q1 2026.

  • Quarterly EBT fell 774.12% year-over-year to -$363.7 million in Q1 2026, while the trailing twelve-month figure through Mar 2026 was -$515.6 million (down 89.85% YoY) and the FY2025 annual result came in at -$306.6 million, down 154.92% from the prior year.
  • EBT was -$363.7 million for Q1 2026 at Tyra Biosciences, down from -$34.0 million in the prior quarter.
  • Across five years, EBT topped out at -$13.0 million in Q4 2022 and bottomed at -$363.7 million in Q1 2026.
  • A 5-year average of -$69.3 million and a median of -$41.9 million in 2025 frame the typical range for EBT.
  • Annual changes were most pronounced in 2025 — EBT soared 44.54% — and 2026, when it tumbled 774.12%.
  • Tyra Biosciences' EBT stood at -$13.0 million in 2022, then tumbled by 76.13% to -$22.8 million in 2023, then retreated by 13.32% to -$25.9 million in 2024, then sank by 31.55% to -$34.0 million in 2025, then plunged by 968.75% to -$363.7 million in 2026.
  • Business Quant data shows TYRA's EBT at -$363.7 million in Q1 2026, -$34.0 million in Q4 2025, and -$75.9 million in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBT (Qtr)
1 Oculis Holding AG 68,785.72 Bn 68,785.72 Bn - -36.97 Mn
2 Nanobiotix 1,895.57 Bn 1,895.51 Bn - -
3 BeOne Medicines 471.35 Bn 466.56 Bn 1.35 Bn 259.22 Mn
4 NuCana 279.75 Bn 279.75 Bn - -3.49 Mn
5 Vertex Pharmaceuticals 120.24 Bn 113.00 Bn 2.59 Bn 1.25 Bn
6 Regeneron Pharmaceuticals 67.80 Bn 59.04 Bn 3.31 Bn 831.20 Mn
7 Belite Bio 62.51 Bn 62.51 Bn - -26.94 Mn
8 Argenx Se 57.38 Bn 57.38 Bn 1.41 Bn 541.00 Mn
9 Revolution Medicines 37.78 Bn 37.78 Bn - -453.82 Mn
10 Tyra Biosciences 1.90 Bn 1.90 Bn - -363.74 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 -363.74 Mn
Dec 31, 2025 -34.03 Mn
Sep 30, 2025 -75.89 Mn
Jun 30, 2025 -41.89 Mn
Mar 31, 2025 -41.61 Mn
Dec 31, 2024 -25.87 Mn
Sep 30, 2024 -135.01 Mn
Jun 30, 2024 -69.07 Mn
Mar 31, 2024 -75.03 Mn
Dec 31, 2023 -22.83 Mn
Sep 30, 2023 -61.13 Mn
Jun 30, 2023 -70.61 Mn
Mar 31, 2023 -67.78 Mn
Dec 31, 2022 -12.96 Mn
Sep 30, 2022 -31.32 Mn
Jun 30, 2022 -15.17 Mn
Mar 31, 2022 -34.75 Mn
Dec 31, 2021 -9.93 Mn
Sep 30, 2021 -44.68 Mn
Jun 30, 2021 -5.60 Mn