Tyra Biosciences (TYRA) EBITDA (2020 - 2026)

Tyra Biosciences (TYRA) reported EBITDA of -$39.6 million for Q1 2026, down 40.25% on a YoY basis from -$66.3 million in Q1 2025, and down 16.85% quarter-over-quarter from -$33.9 million in Q4 2025.

Tyra Biosciences (TYRA) EBITDA (2020 - 2026) Analysis & Trends

Tyra Biosciences has reported EBITDA for 7 years, with the latest figure at -$39.6 million in Q1 2026.

  • For the quarter ending Q1 2026, EBITDA fell 40.25% year-over-year to -$39.6 million; the trailing twelve-month figure through Mar 2026 stood at -$131.7 million (down 37.54% YoY), and the FY2025 full-year result was -$120.3 million, down 39.76% from the prior year.
  • EBITDA for Q1 2026 stood at -$39.6 million, down from -$33.9 million in the prior quarter.
  • The five-year high for EBITDA was -$11.9 million in Q1 2023, with the low at -$39.6 million in Q1 2026.
  • Historically, EBITDA has averaged -$22.0 million across 5 years, with a median of -$21.2 million in 2023.
  • Annual changes were most pronounced in 2022 — EBITDA plunged 252.27% — and 2023, when it increased 19.91%.
  • Tyra Biosciences' EBITDA stood at -$15.0 million in 2022, then sank by 49.48% to -$22.4 million in 2023, then decreased by 18.28% to -$26.6 million in 2024, then fell by 27.61% to -$33.9 million in 2025, then retreated by 16.85% to -$39.6 million in 2026.
  • The last three EBITDA figures came in at -$39.6 million (Q1 2026), -$33.9 million (Q4 2025), and -$29.9 million (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBITDA (Qtr)
1 Alterity Therapeutics 814,307.08 Bn 814,307.05 Bn - -
2 Belite Bio 55,320.00 Bn 55,320.00 Bn - -26.92 Mn
3 Quantum Biopharma 17,149.72 Bn 17,149.72 Bn - -13.63 Mn
4 Legend Biotech 3,590.00 Bn 3,589.71 Bn 242.10 Mn -19.70 Mn
5 Akari Therapeutics 1,650.72 Bn 1,650.72 Bn - -14.44 Mn
6 Evaxion A 1,522.09 Bn 1,522.07 Bn - -3.82 Mn
7 Psyence Biomedical 229.39 Bn 229.38 Bn - -752,618.00
8 Vertex Pharmaceuticals 113.09 Bn 105.85 Bn 2.59 Bn 1.14 Bn
9 Abivax 90.15 Bn 90.15 Bn - -65.83 Mn
10 Tyra Biosciences 1.67 Bn 1.67 Bn - -39.59 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 -39.59 Mn
Dec 31, 2025 -33.88 Mn
Sep 30, 2025 -29.86 Mn
Jun 30, 2025 -28.35 Mn
Mar 31, 2025 -28.23 Mn
Dec 31, 2024 -26.55 Mn
Sep 30, 2024 -22.08 Mn
Jun 30, 2024 -18.88 Mn
Mar 31, 2024 -18.58 Mn
Dec 31, 2023 -22.45 Mn
Sep 30, 2023 -21.15 Mn
Jun 30, 2023 -13.27 Mn
Mar 31, 2023 -11.88 Mn
Dec 31, 2022 -15.02 Mn
Sep 30, 2022 -13.65 Mn
Jun 30, 2022 -15.43 Mn
Mar 31, 2022 -14.83 Mn
Dec 31, 2021 -9.93 Mn
Sep 30, 2021 -6.64 Mn
Jun 30, 2021 -5.51 Mn