Tyra Biosciences (TYRA) EBITDA (2020 - 2026)
Tyra Biosciences (TYRA) reported EBITDA of -$39.6 million for Q1 2026, down 40.25% on a YoY basis from -$66.3 million in Q1 2025, and down 16.85% quarter-over-quarter from -$33.9 million in Q4 2025.
Tyra Biosciences (TYRA) EBITDA (2020 - 2026) Analysis & Trends
Tyra Biosciences has reported EBITDA for 7 years, with the latest figure at -$39.6 million in Q1 2026.
- For the quarter ending Q1 2026, EBITDA fell 40.25% year-over-year to -$39.6 million; the trailing twelve-month figure through Mar 2026 stood at -$131.7 million (down 37.54% YoY), and the FY2025 full-year result was -$120.3 million, down 39.76% from the prior year.
- EBITDA for Q1 2026 stood at -$39.6 million, down from -$33.9 million in the prior quarter.
- The five-year high for EBITDA was -$11.9 million in Q1 2023, with the low at -$39.6 million in Q1 2026.
- Historically, EBITDA has averaged -$22.0 million across 5 years, with a median of -$21.2 million in 2023.
- Annual changes were most pronounced in 2022 — EBITDA plunged 252.27% — and 2023, when it increased 19.91%.
- Tyra Biosciences' EBITDA stood at -$15.0 million in 2022, then sank by 49.48% to -$22.4 million in 2023, then decreased by 18.28% to -$26.6 million in 2024, then fell by 27.61% to -$33.9 million in 2025, then retreated by 16.85% to -$39.6 million in 2026.
- The last three EBITDA figures came in at -$39.6 million (Q1 2026), -$33.9 million (Q4 2025), and -$29.9 million (Q3 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | EBITDA (Qtr) |
|---|---|---|---|---|---|
| 1 | Alterity Therapeutics | 814,307.08 Bn | 814,307.05 Bn | - | - |
| 2 | Belite Bio | 55,320.00 Bn | 55,320.00 Bn | - | -26.92 Mn |
| 3 | Quantum Biopharma | 17,149.72 Bn | 17,149.72 Bn | - | -13.63 Mn |
| 4 | Legend Biotech | 3,590.00 Bn | 3,589.71 Bn | 242.10 Mn | -19.70 Mn |
| 5 | Akari Therapeutics | 1,650.72 Bn | 1,650.72 Bn | - | -14.44 Mn |
| 6 | Evaxion A | 1,522.09 Bn | 1,522.07 Bn | - | -3.82 Mn |
| 7 | Psyence Biomedical | 229.39 Bn | 229.38 Bn | - | -752,618.00 |
| 8 | Vertex Pharmaceuticals | 113.09 Bn | 105.85 Bn | 2.59 Bn | 1.14 Bn |
| 9 | Abivax | 90.15 Bn | 90.15 Bn | - | -65.83 Mn |
| 10 | Tyra Biosciences | 1.67 Bn | 1.67 Bn | - | -39.59 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -39.59 Mn |
| Dec 31, 2025 | -33.88 Mn |
| Sep 30, 2025 | -29.86 Mn |
| Jun 30, 2025 | -28.35 Mn |
| Mar 31, 2025 | -28.23 Mn |
| Dec 31, 2024 | -26.55 Mn |
| Sep 30, 2024 | -22.08 Mn |
| Jun 30, 2024 | -18.88 Mn |
| Mar 31, 2024 | -18.58 Mn |
| Dec 31, 2023 | -22.45 Mn |
| Sep 30, 2023 | -21.15 Mn |
| Jun 30, 2023 | -13.27 Mn |
| Mar 31, 2023 | -11.88 Mn |
| Dec 31, 2022 | -15.02 Mn |
| Sep 30, 2022 | -13.65 Mn |
| Jun 30, 2022 | -15.43 Mn |
| Mar 31, 2022 | -14.83 Mn |
| Dec 31, 2021 | -9.93 Mn |
| Sep 30, 2021 | -6.64 Mn |
| Jun 30, 2021 | -5.51 Mn |