Trevi Therapeutics (TRVI) Research & Development (2018 - 2025)

Trevi Therapeutics' (TRVI) quarterly Research & Development came in at $6.2 million in Q4 2025, down 33.61% year-on-year from $9.3 million in Q4 2024, and down 38.59% quarter-over-quarter from $10.1 million in Q3 2025.

Trevi Therapeutics (TRVI) Research & Development (2018 - 2025) Analysis & Trends

Trevi Therapeutics' Research & Development history runs 8 years deep, the most recent figure standing at $6.2 million for Q4 2025.

  • On a quarterly basis, Research & Development fell 33.61% year-over-year to $6.2 million in Q4 2025; TTM through Dec 2025 was $35.0 million, a 11.13% decrease from a year earlier, with the FY2025 full-year figure at $33.5 million, down 14.98% from the prior year.
  • Research & Development retreated to $6.2 million in Q4 2025 per TRVI's latest filing, from $10.1 million in the prior quarter.
  • Across five years, Research & Development topped out at $11.2 million in Q3 2024 and bottomed at $4.3 million in Q4 2022.
  • The 5-year median for Research & Development is $6.2 million (2025), against an average of $6.9 million.
  • Across the five-year window, Research & Development surged 77.51% in 2024 and sank 33.61% in 2025, its largest moves.
  • Year by year, Research & Development stood at $6.2 million in 2021, then slumped by 30.13% to $4.3 million in 2022, then soared by 50.98% to $6.5 million in 2023, then soared by 43.11% to $9.3 million in 2024, then plunged by 33.61% to $6.2 million in 2025.
  • Per Business Quant, the three latest TRVI Research & Development figures stand at $6.2 million (Q4 2025), $10.1 million (Q3 2025), and $9.4 million (Q2 2025).

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) R&D (Qtr)
1 Oculis Holding AG 67,072.09 Bn 67,072.09 Bn - -17.94 Mn
2 Nanobiotix 1,894.61 Bn 1,894.55 Bn - -
3 Akari Therapeutics 1,014.18 Bn 1,014.18 Bn - 1.46 Mn
4 BeOne Medicines 471.64 Bn 466.85 Bn 1.35 Bn 541.22 Mn
5 Vertex Pharmaceuticals 121.72 Bn 114.47 Bn 2.59 Bn 961.60 Mn
6 Regeneron Pharmaceuticals 68.28 Bn 59.52 Bn 3.31 Bn 1.54 Bn
7 Belite Bio 61.40 Bn 61.40 Bn - 15.66 Mn
8 Argenx Se 56.94 Bn 56.94 Bn 1.18 Bn -443.00 Mn
9 Revolution Medicines 37.37 Bn 37.37 Bn - 343.97 Mn
10 Trevi Therapeutics 2.54 Bn 2.54 Bn - -

Historic Data

Download Data
DateValue
Dec 31, 2025 6.19 Mn
Sep 30, 2025 10.09 Mn
Jun 30, 2025 9.39 Mn
Dec 31, 2024 9.33 Mn
Sep 30, 2024 11.22 Mn
Jun 30, 2024 10.02 Mn
Mar 31, 2024 8.80 Mn
Dec 31, 2023 6.52 Mn
Sep 30, 2023 6.32 Mn
Jun 30, 2023 5.84 Mn
Mar 31, 2023 5.00 Mn
Dec 31, 2022 4.32 Mn
Sep 30, 2022 5.77 Mn
Jun 30, 2022 5.10 Mn
Mar 31, 2022 4.65 Mn
Dec 31, 2021 6.18 Mn
Sep 30, 2021 4.72 Mn
Jun 30, 2021 6.50 Mn
Mar 31, 2021 5.59 Mn
Dec 31, 2020 6.56 Mn