Trevi Therapeutics (TRVI) Research & Development (2018 - 2025)
Trevi Therapeutics (TRVI) recorded quarterly Research & Development of $6.2 million in Q4 2025, down 38.59% quarter-over-quarter from $10.1 million in Q3 2025, and down 33.61% on a YoY basis from $9.3 million in Q4 2024.
Trevi Therapeutics (TRVI) Research & Development (2018 - 2025) Analysis & Trends
Trevi Therapeutics' Research & Development history runs 8 years deep, the most recent figure standing at $6.2 million for Q4 2025.
- In Q4 2025, Research & Development fell 33.61% year-over-year to $6.2 million; the TTM figure through Dec 2025 stood at $35.0 million (down 11.13% YoY), while the FY2025 annual figure was $33.5 million, down 14.98% from the prior year.
- Research & Development was $6.2 million for Q4 2025 at Trevi Therapeutics, down from $10.1 million in the prior quarter.
- In the past five years, Research & Development ranged from a high of $11.2 million in Q3 2024 to a low of $4.3 million in Q4 2022.
- Historically, Research & Development has averaged $6.9 million across 5 years, with a median of $6.2 million in 2025.
- The sharpest annual moves came in 2024 and 2025: Research & Development soared 77.51% in 2024, then sank 33.61% in 2025.
- A 5-year view of Research & Development shows it stood at $6.2 million in 2021, then plunged by 30.13% to $4.3 million in 2022, then soared by 50.98% to $6.5 million in 2023, then soared by 43.11% to $9.3 million in 2024, then slumped by 33.61% to $6.2 million in 2025.
- The last three Research & Development figures came in at $6.2 million (Q4 2025), $10.1 million (Q3 2025), and $9.4 million (Q2 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | R&D (Qtr) |
|---|---|---|---|---|---|
| 1 | Alterity Therapeutics | 925,601.88 Bn | 925,601.85 Bn | - | 4.32 Mn |
| 2 | Belite Bio | 58,560.00 Bn | 58,560.00 Bn | - | 15.66 Mn |
| 3 | Quantum Biopharma | 17,284.41 Bn | 17,284.40 Bn | - | 626,092.00 |
| 4 | Legend Biotech | 2,809.00 Bn | 2,808.71 Bn | 242.10 Mn | -101.30 Mn |
| 5 | Evaxion A | 1,334.43 Bn | 1,334.42 Bn | - | -2.30 Mn |
| 6 | Akari Therapeutics | 1,312.27 Bn | 1,312.26 Bn | - | 1.46 Mn |
| 7 | Psyence Biomedical | 212.16 Bn | 212.16 Bn | - | 357,444.00 |
| 8 | Vertex Pharmaceuticals | 114.83 Bn | 107.58 Bn | 2.59 Bn | 961.60 Mn |
| 9 | Abivax | 91.96 Bn | 91.96 Bn | - | -58.00 Mn |
| 10 | Trevi Therapeutics | 2.50 Bn | 2.33 Bn | - | - |
Historic Data
Download Data| Date | Value |
|---|---|
| Dec 31, 2025 | 6.19 Mn |
| Sep 30, 2025 | 10.09 Mn |
| Jun 30, 2025 | 9.39 Mn |
| Dec 31, 2024 | 9.33 Mn |
| Sep 30, 2024 | 11.22 Mn |
| Jun 30, 2024 | 10.02 Mn |
| Mar 31, 2024 | 8.80 Mn |
| Dec 31, 2023 | 6.52 Mn |
| Sep 30, 2023 | 6.32 Mn |
| Jun 30, 2023 | 5.84 Mn |
| Mar 31, 2023 | 5.00 Mn |
| Dec 31, 2022 | 4.32 Mn |
| Sep 30, 2022 | 5.77 Mn |
| Jun 30, 2022 | 5.10 Mn |
| Mar 31, 2022 | 4.65 Mn |
| Dec 31, 2021 | 6.18 Mn |
| Sep 30, 2021 | 4.72 Mn |
| Jun 30, 2021 | 6.50 Mn |
| Mar 31, 2021 | 5.59 Mn |
| Dec 31, 2020 | 6.56 Mn |