Trevi Therapeutics (TRVI) Research & Development (2018 - 2025)

Trevi Therapeutics (TRVI) recorded quarterly Research & Development of $6.2 million in Q4 2025, down 38.59% quarter-over-quarter from $10.1 million in Q3 2025, and down 33.61% on a YoY basis from $9.3 million in Q4 2024.

Trevi Therapeutics (TRVI) Research & Development (2018 - 2025) Analysis & Trends

Trevi Therapeutics' Research & Development history runs 8 years deep, the most recent figure standing at $6.2 million for Q4 2025.

  • In Q4 2025, Research & Development fell 33.61% year-over-year to $6.2 million; the TTM figure through Dec 2025 stood at $35.0 million (down 11.13% YoY), while the FY2025 annual figure was $33.5 million, down 14.98% from the prior year.
  • Research & Development was $6.2 million for Q4 2025 at Trevi Therapeutics, down from $10.1 million in the prior quarter.
  • In the past five years, Research & Development ranged from a high of $11.2 million in Q3 2024 to a low of $4.3 million in Q4 2022.
  • Historically, Research & Development has averaged $6.9 million across 5 years, with a median of $6.2 million in 2025.
  • The sharpest annual moves came in 2024 and 2025: Research & Development soared 77.51% in 2024, then sank 33.61% in 2025.
  • A 5-year view of Research & Development shows it stood at $6.2 million in 2021, then plunged by 30.13% to $4.3 million in 2022, then soared by 50.98% to $6.5 million in 2023, then soared by 43.11% to $9.3 million in 2024, then slumped by 33.61% to $6.2 million in 2025.
  • The last three Research & Development figures came in at $6.2 million (Q4 2025), $10.1 million (Q3 2025), and $9.4 million (Q2 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) R&D (Qtr)
1 Alterity Therapeutics 925,601.88 Bn 925,601.85 Bn - 4.32 Mn
2 Belite Bio 58,560.00 Bn 58,560.00 Bn - 15.66 Mn
3 Quantum Biopharma 17,284.41 Bn 17,284.40 Bn - 626,092.00
4 Legend Biotech 2,809.00 Bn 2,808.71 Bn 242.10 Mn -101.30 Mn
5 Evaxion A 1,334.43 Bn 1,334.42 Bn - -2.30 Mn
6 Akari Therapeutics 1,312.27 Bn 1,312.26 Bn - 1.46 Mn
7 Psyence Biomedical 212.16 Bn 212.16 Bn - 357,444.00
8 Vertex Pharmaceuticals 114.83 Bn 107.58 Bn 2.59 Bn 961.60 Mn
9 Abivax 91.96 Bn 91.96 Bn - -58.00 Mn
10 Trevi Therapeutics 2.50 Bn 2.33 Bn - -

Historic Data

Download Data
DateValue
Dec 31, 2025 6.19 Mn
Sep 30, 2025 10.09 Mn
Jun 30, 2025 9.39 Mn
Dec 31, 2024 9.33 Mn
Sep 30, 2024 11.22 Mn
Jun 30, 2024 10.02 Mn
Mar 31, 2024 8.80 Mn
Dec 31, 2023 6.52 Mn
Sep 30, 2023 6.32 Mn
Jun 30, 2023 5.84 Mn
Mar 31, 2023 5.00 Mn
Dec 31, 2022 4.32 Mn
Sep 30, 2022 5.77 Mn
Jun 30, 2022 5.10 Mn
Mar 31, 2022 4.65 Mn
Dec 31, 2021 6.18 Mn
Sep 30, 2021 4.72 Mn
Jun 30, 2021 6.50 Mn
Mar 31, 2021 5.59 Mn
Dec 31, 2020 6.56 Mn