Growth Metrics

Trevi Therapeutics (TRVI) Research & Development (2018 - 2025)

Trevi Therapeutics' quarterly Research & Development came in at $6.2 million in Q4 2025, down 33.61% year-on-year from $9.3 million in Q4 2024, and down 38.59% quarter-over-quarter from $10.1 million in Q3 2025.

Trevi Therapeutics has reported Research & Development for 8 years, with the latest figure at $6.2 million in Q4 2025.

  • For the quarter ending Q4 2025, Research & Development fell 33.61% year-over-year to $6.2 million; the trailing twelve-month figure through Dec 2025 stood at $35.0 million (down 11.13% YoY), and the FY2025 full-year result was $33.5 million, down 14.98% from the prior year.
  • Research & Development for Q4 2025 stood at $6.2 million, down from $10.1 million in the prior quarter.
  • The five-year high for Research & Development was $11.2 million in Q3 2024, with the low at $4.3 million in Q4 2022.
  • Average Research & Development over 5 years is $6.9 million, with a median of $6.2 million recorded in 2025.
  • Year-over-year, Research & Development surged 77.51% in 2024 and sank 33.61% in 2025.
  • Tracing TRVI's Research & Development over 5 years: stood at $6.2 million in 2021, then tumbled by 30.13% to $4.3 million in 2022, then jumped by 50.98% to $6.5 million in 2023, then jumped by 43.11% to $9.3 million in 2024, then sank by 33.61% to $6.2 million in 2025.
  • The last three Research & Development figures came in at $6.2 million (Q4 2025), $10.1 million (Q3 2025), and $9.4 million (Q2 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) R&D (Qtr)
1 Quantum Biopharma 961,148.99 Bn 961,148.98 Bn - 626,092.00
2 Alterity Therapeutics 744,933.29 Bn 744,933.26 Bn - 4.32 Mn
3 Legend Biotech 2,540.00 Bn 2,539.71 Bn 242.10 Mn -101.30 Mn
4 Nanobiotix 2,199.85 Bn 2,199.78 Bn - -
5 Akari Therapeutics 1,635.88 Bn 1,635.88 Bn - 1.46 Mn
6 Vertex Pharmaceuticals 111.32 Bn 104.07 Bn 2.59 Bn 961.60 Mn
7 Evaxion A 62.56 Bn 62.54 Bn - -2.30 Mn
8 Regeneron Pharmaceuticals 62.55 Bn 53.79 Bn 3.31 Bn 1.54 Bn
9 Alnylam Pharmaceuticals 39.57 Bn 36.56 Bn 959.66 Mn 364.87 Mn
10 Trevi Therapeutics 2.02 Bn 1.85 Bn - -

Historic Data

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DateValue
Dec 31, 2025 6.19 Mn
Sep 30, 2025 10.09 Mn
Jun 30, 2025 9.39 Mn
Dec 31, 2024 9.33 Mn
Sep 30, 2024 11.22 Mn
Jun 30, 2024 10.02 Mn
Mar 31, 2024 8.80 Mn
Dec 31, 2023 6.52 Mn
Sep 30, 2023 6.32 Mn
Jun 30, 2023 5.84 Mn
Mar 31, 2023 5.00 Mn
Dec 31, 2022 4.32 Mn
Sep 30, 2022 5.77 Mn
Jun 30, 2022 5.10 Mn
Mar 31, 2022 4.65 Mn
Dec 31, 2021 6.18 Mn
Sep 30, 2021 4.72 Mn
Jun 30, 2021 6.50 Mn
Mar 31, 2021 5.59 Mn
Dec 31, 2020 6.56 Mn
Sep 30, 2020 4.83 Mn
Jun 30, 2020 4.92 Mn
Mar 31, 2020 6.02 Mn
Dec 31, 2019 4.82 Mn
Sep 30, 2019 5.65 Mn
Jun 30, 2019 5.53 Mn
Mar 31, 2019 3.34 Mn
Dec 31, 2018 4.52 Mn
Sep 30, 2018 3.75 Mn
Jun 30, 2018 3.44 Mn
Mar 31, 2018 2.36 Mn