Spyre Therapeutics (SYRE) Short-term Investments (2015 - 2026)
Spyre Therapeutics' Short-term Investments was $983.34 million in Q2 2026, up 121.0% from $444.92 million a year earlier and up 52.6% from the prior quarter.
Spyre Therapeutics (SYRE) Short-term Investments (2015 - 2026) Analysis & Trends
At the end of FY2025, Short-term Investments at Spyre Therapeutics came in at $670.81 million, up 30.6% from FY2024.
- Short-term Investments has now increased for three consecutive years, with a five-year compound annual growth rate of 64.2% (FY2020 to FY2025).
- In earlier years, Short-term Investments was $513.67 million in FY2024 (+241.6%), $150.38 million in FY2023 (+621.3%), $20.85 million in FY2022 (-73.3%) and $77.99 million in FY2021 (+38.8%).
- The Q2 2026 figure marks the highest quarterly Short-term Investments in data going back to Q4 2015.
- Compared with a year earlier, Short-term Investments has increased for eight straight quarters, with growth averaging 95.2% over the last eight quarters.
- The best year-over-year quarter for Short-term Investments over five years was Q4 2023 (growth of 621.3%); the worst was Q1 2023 (a decline of 93.8%).
- Per Business Quant data, SYRE's Short-term Investments in the three quarters before Q2 2026 was $644.28 million (Q1 2026), $670.81 million (Q4 2025) and $421.3 million (Q3 2025).
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) |
|---|---|---|---|---|
| 1 | Eli Lilly | 1,137.66 Bn | 1,106.24 Bn | 19.71 Bn |
| 2 | Johnson & Johnson | 636.13 Bn | 556.00 Bn | 17.30 Bn |
| 3 | AbbVie | 505.28 Bn | 478.39 Bn | 12.70 Bn |
| 4 | Merck | 358.10 Bn | 312.48 Bn | 12.21 Bn |
| 5 | Novartis Ag | 292.59 Bn | 256.58 Bn | 11.24 Bn |
| 6 | Astrazeneca | 265.81 Bn | 239.50 Bn | 12.86 Bn |
| 7 | Amgen | 237.53 Bn | 192.93 Bn | 7.24 Bn |
| 8 | Gilead Sciences | 194.67 Bn | 168.86 Bn | 6.22 Bn |
| 9 | Pfizer | 171.17 Bn | 117.82 Bn | 10.94 Bn |
| 10 | Spyre Therapeutics | 7.68 Bn | 4.55 Bn | - |
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | 983.34 Mn |
| Mar 31, 2026 | 644.28 Mn |
| Dec 31, 2025 | 670.81 Mn |
| Sep 30, 2025 | 421.30 Mn |
| Jun 30, 2025 | 444.92 Mn |
| Mar 31, 2025 | 516.33 Mn |
| Dec 31, 2024 | 513.67 Mn |
| Sep 30, 2024 | 342.65 Mn |
| Jun 30, 2024 | 380.85 Mn |
| Mar 31, 2024 | 257.09 Mn |
| Dec 31, 2023 | 150.38 Mn |
| Sep 30, 2023 | 113.01 Mn |
| Mar 31, 2023 | 3.24 Mn |
| Dec 31, 2022 | 20.85 Mn |
| Sep 30, 2022 | 34.69 Mn |
| Jun 30, 2022 | 51.08 Mn |
| Mar 31, 2022 | 52.09 Mn |
| Dec 31, 2021 | 77.99 Mn |
| Sep 30, 2021 | 87.76 Mn |
| Jun 30, 2021 | 93.81 Mn |
Spyre Therapeutics Short-term Investments API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=short-term-investments&ticker=SYRE&period=max&api_key=YOUR_API_KEY
import requests
url = "https://data.businessquant.com/historic"
params = {"slug": "short-term-investments", "ticker": "SYRE", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()
const res = await fetch("https://data.businessquant.com/historic?slug=short-term-investments&ticker=SYRE&period=max&api_key=YOUR_API_KEY");
const data = await res.json();