Spyre Therapeutics (SYRE) Shares Outstanding (Entity) (2015 - 2026)
Spyre Therapeutics' Shares Outstanding (Entity) was 88.06 million in Q2 2026, up 45.9% from 60.37 million a year earlier and up 11.7% from the prior quarter.
Spyre Therapeutics (SYRE) Shares Outstanding (Entity) (2015 - 2026) Analysis & Trends
For FY2025, Shares Outstanding (Entity) at Spyre Therapeutics came in at 64.42 million, up 35.7% from FY2024.
- Shares Outstanding (Entity) has now increased for nine consecutive years, with a five-year compound annual growth rate of 101.9% (FY2020 to FY2025).
- In earlier years, Shares Outstanding (Entity) was 47.49 million in FY2024 (+546.9%), 7.34 million in FY2023 (+117.7%), 3.37 million in FY2022 (+28.2%) and 2.63 million in FY2021 (+37.1%).
- The Q2 2026 figure marks the highest quarterly Shares Outstanding (Entity) in data going back to Q1 2015.
- Compared with a year earlier, Shares Outstanding (Entity) has increased for seven straight quarters, with growth averaging 108.6% over the last seven quarters.
- The best year-over-year quarter for Shares Outstanding (Entity) over five years was Q1 2024 (growth of 871.5%); the worst was Q2 2023 (a decline of 1.5%).
- Per Business Quant data, SYRE's Shares Outstanding (Entity) in the three quarters before Q2 2026 was 78.84 million (Q1 2026), 64.42 million (Q4 2025) and 60.47 million (Q3 2025).
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Shares Outstanding (Entity.) (Qtr) |
|---|---|---|---|---|---|
| 1 | Johnson & Johnson | 638.12 Bn | 556.64 Bn | 17.26 Bn | 2.41 Bn |
| 2 | AbbVie | 462.60 Bn | 435.75 Bn | 12.70 Bn | 1.77 Bn |
| 3 | Merck | 358.70 Bn | 313.13 Bn | 12.21 Bn | 2.47 Bn |
| 4 | Novartis Ag | 272.16 Bn | 228.03 Bn | 11.24 Bn | - |
| 5 | Astrazeneca | 250.36 Bn | 223.92 Bn | 12.86 Bn | - |
| 6 | Amgen | 227.87 Bn | 183.27 Bn | 7.24 Bn | 540.60 Mn |
| 7 | Gilead Sciences | 184.97 Bn | 159.08 Bn | 6.22 Bn | 1.24 Bn |
| 8 | Pfizer | 162.61 Bn | 109.56 Bn | 10.94 Bn | 5.70 Bn |
| 9 | Vertex Pharmaceuticals | 132.45 Bn | 104.46 Bn | 2.84 Bn | 253.35 Mn |
| 10 | Spyre Therapeutics | 7.84 Bn | 7.84 Bn | - | 88.06 Mn |
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | 88.06 Mn |
| Mar 31, 2026 | 78.84 Mn |
| Dec 31, 2025 | 64.42 Mn |
| Sep 30, 2025 | 60.47 Mn |
| Jun 30, 2025 | 60.37 Mn |
| Mar 31, 2025 | 60.28 Mn |
| Dec 31, 2024 | 47.49 Mn |
| Sep 30, 2024 | 51.40 Mn |
| Jun 30, 2024 | 50.78 Mn |
| Mar 31, 2024 | 36.63 Mn |
| Dec 31, 2023 | 7.34 Mn |
| Sep 30, 2023 | 4.05 Mn |
| Jun 30, 2023 | 3.24 Mn |
| Mar 31, 2023 | 3.77 Mn |
| Dec 31, 2022 | 3.37 Mn |
| Sep 30, 2022 | 3.77 Mn |
| Jun 30, 2022 | 3.29 Mn |
| Mar 31, 2022 | 2.64 Mn |
| Dec 31, 2021 | 2.63 Mn |
| Sep 30, 2021 | 2.63 Mn |
Spyre Therapeutics Shares Outstanding (Entity) API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=shares-outstanding-entity&ticker=SYRE&period=max&api_key=YOUR_API_KEY
import requests
url = "https://data.businessquant.com/historic"
params = {"slug": "shares-outstanding-entity", "ticker": "SYRE", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()
const res = await fetch("https://data.businessquant.com/historic?slug=shares-outstanding-entity&ticker=SYRE&period=max&api_key=YOUR_API_KEY");
const data = await res.json();