Spyre Therapeutics SYRE
NASDAQ SYRE
$93.19 +3.26 (+3.63%)
At close: Oct 2, 2026 · 4:00 PM EDT

Spyre Therapeutics (SYRE) Shares Outstanding (Diluted) (2020 - 2026)

Updated

Spyre Therapeutics (SYRE) reported Shares Outstanding (Diluted) of 85.09 million for Q2 2026, up 41.0% from 60.33 million a year earlier and up 7.8% from the prior quarter.

Analysis

Spyre Therapeutics (SYRE) Shares Outstanding (Diluted) (2020 - 2026) Analysis & Trends

For FY2025, Spyre Therapeutics posted Shares Outstanding (Diluted) of 64.06 million, up 34.9% from FY2024.

  • Shares Outstanding (Diluted) has increased for five consecutive years, with a five-year compound annual growth rate of 97.4% (FY2020 to FY2025).
  • By year, Shares Outstanding (Diluted) came in at 47.49 million in FY2024 (+546.9%), 7.34 million in FY2023 (+117.7%), 3.37 million in FY2022 (+28.2%) and 2.63 million in FY2021 (+23.2%).
  • The Q2 2026 figure ranks as the highest quarterly Shares Outstanding (Diluted) in data going back to Q4 2020.
  • Year over year, Shares Outstanding (Diluted) has now increased in each of the last eight quarters, with growth averaging 202.8% over the last eight quarters.
  • The high point for year-over-year Shares Outstanding (Diluted) in five years was Q1 2024 (growth of 884.4%); the low point was Q2 2023 (a decline of 95.3%).
  • Per Business Quant data, the three quarters before Q2 2026 came in at 78.91 million (Q1 2026), 64.06 million (Q4 2025) and 60.41 million (Q3 2025).
Peer Set

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Shares Outstanding (Dil.) (Qtr)
1 Eli Lilly 1,076.25 Bn 1,044.84 Bn 19.71 Bn 893.70 Mn
2 Johnson & Johnson 617.18 Bn 535.70 Bn 17.26 Bn 2.44 Bn
3 AbbVie 464.58 Bn 437.73 Bn 12.70 Bn 1.77 Bn
4 Merck 356.04 Bn 310.47 Bn 12.21 Bn 2.47 Bn
5 Novartis Ag 269.07 Bn 224.94 Bn 11.24 Bn 1.96 Bn
6 Astrazeneca 243.21 Bn 216.77 Bn 12.86 Bn 1.56 Bn
7 Amgen 217.88 Bn 173.28 Bn 7.24 Bn 544.00 Mn
8 Gilead Sciences 179.62 Bn 153.74 Bn 6.22 Bn 1.24 Bn
9 Pfizer 158.45 Bn 105.40 Bn 10.94 Bn 5.70 Bn
10 Spyre Therapeutics 8.21 Bn 8.21 Bn - 85.09 Mn
Historic Data

Historic Data

Download Data
DateValue
Jun 30, 2026 85.09 Mn
Mar 31, 2026 78.91 Mn
Dec 31, 2025 64.06 Mn
Sep 30, 2025 60.41 Mn
Jun 30, 2025 60.33 Mn
Mar 31, 2025 60.27 Mn
Dec 31, 2024 47.49 Mn
Sep 30, 2024 51.25 Mn
Jun 30, 2024 45.83 Mn
Mar 31, 2024 37.12 Mn
Dec 31, 2023 7.34 Mn
Sep 30, 2023 5.36 Mn
Jun 30, 2023 154,490.00
Mar 31, 2023 3.77 Mn
Dec 31, 2022 3.37 Mn
Sep 30, 2022 3.77 Mn
Jun 30, 2022 3.29 Mn
Mar 31, 2022 2.64 Mn
Dec 31, 2021 2.63 Mn
Sep 30, 2021 2.63 Mn
API Access

Spyre Therapeutics Shares Outstanding (Diluted) API

Pull this series into your own models, spreadsheets and apps with the Business Quant Historical Metrics API. The request below matches the chart above — change the frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.

https://data.businessquant.com/historic?slug=shares-outstanding-diluted&ticker=SYRE&period=max&api_key=YOUR_API_KEY