Spyre Therapeutics SYRE
NASDAQ SYRE
$103.82 -3.00 (-2.80%)
As of: Nov 12, 2026 · 10:51 AM EST

Spyre Therapeutics (SYRE) Return on Sales [ROS] (2017 - 2024)

Updated

Spyre Therapeutics' Return on Sales [ROS] came in at -39428.92% for Q1 2024, down 29930.94 percentage points from -9497.98% a year earlier and down 12080.96 percentage points from the prior quarter.

Analysis

Spyre Therapeutics (SYRE) Return on Sales [ROS] (2017 - 2024) Analysis & Trends

For FY2023, Spyre Therapeutics' Return on Sales [ROS] was -27347.97%, down 23707.74 percentage points from FY2022.

  • Return on Sales [ROS] carries a five-year change of -26182.25 percentage points (FY2018 to FY2023).
  • Going back by year, Return on Sales [ROS] was -3640.23% in FY2022 (-3289.90 pp) and -350.33% in FY2021.
  • The Q1 2024 figure represents the lowest quarterly Return on Sales [ROS] in data going back to Q1 2017.
  • Year-over-year, Return on Sales [ROS] has declined for eight consecutive quarters, with an average year-over-year change of -13314.86 percentage points over the last eight quarters.
  • Across the past five years, year-over-year drop in Return on Sales [ROS] ran from 3538.72 percentage points in Q2 2022 to 29930.94 percentage points in Q1 2024.
  • Business Quant data shows SYRE's Return on Sales [ROS] at -27347.97% (Q4 2023), -20450.76% (Q3 2023) and -23146.22% (Q2 2023) in the three quarters before Q1 2024.
Peer Set

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) ROS (Qtr)
1 Eli Lilly 1,348.13 Bn 1,321.74 Bn 20.46 Bn 34.46%
2 Johnson & Johnson 675.90 Bn 595.76 Bn 17.30 Bn 24.35%
3 AbbVie 519.45 Bn 487.50 Bn 13.12 Bn 36.01%
4 Merck 364.95 Bn 327.95 Bn 13.19 Bn 30.74%
5 Novartis Ag 311.58 Bn 285.16 Bn - -
6 Astrazeneca 289.34 Bn 262.94 Bn 13.26 Bn 29.12%
7 Amgen 251.64 Bn 203.30 Bn 7.58 Bn 35.79%
8 Gilead Sciences 212.05 Bn 187.07 Bn 6.73 Bn 41.71%
9 Pfizer 167.35 Bn 115.00 Bn 12.56 Bn 32.98%
10 Spyre Therapeutics 9.40 Bn 5.68 Bn - -
Historic Data

Historic Data

Download Data
DateValue
Mar 31, 2024 -39,428.92%
Dec 31, 2023 -27,347.97%
Sep 30, 2023 -20,450.76%
Jun 30, 2023 -23,146.22%
Mar 31, 2023 -9,497.98%
Dec 31, 2022 -11,405.95%
Sep 30, 2022 -10,778.74%
Jun 30, 2022 -3,587.68%
Mar 31, 2022 -1,794.49%
Dec 31, 2021 -560.98%
Sep 30, 2021 -1,450.54%
Jun 30, 2021 -48.96%
Mar 31, 2019 -2,307.61%
Dec 31, 2018 -1,169.32%
Sep 30, 2018 -684.88%
Jun 30, 2018 -406.64%
Mar 31, 2018 -546.03%
Dec 31, 2017 -446.86%
Sep 30, 2017 -634.26%
Jun 30, 2017 -454.36%
API Access

Spyre Therapeutics Return on Sales [ROS] API

Pull this series into your own models, spreadsheets and apps with the Business Quant Historical Metrics API. The request below matches the chart above — change the frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.

https://data.businessquant.com/historic?slug=return-on-sales-%5Bros%5D&ticker=SYRE&period=max&api_key=YOUR_API_KEY