Spyre Therapeutics (SYRE) Price to Book (2016 - 2026)
Spyre Therapeutics' (SYRE) Price to Book came in at 7.62 for Q3 2026, up 242.0% from 2.23 a year earlier and up 7.3% from the prior quarter.
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Analysis
Spyre Therapeutics (SYRE) Price to Book (2016 - 2026) Analysis & Trends
For FY2025, Spyre Therapeutics' Price to Book stood at 2.95, up 38.2% from FY2024.
- In prior years, Spyre Therapeutics' Price to Book was 2.13 in FY2024 (+148.7%), 0.86 in FY2023 (-95.4%), 18.85 in FY2022 (-79.7%) and 93.01 in FY2021 (+37.8%).
- The Q3 2026 figure stands as the highest quarterly Price to Book since Q1 2024.
- On a year-over-year basis, Price to Book has increased in each of the last four quarters, with growth averaging 89.2% over the last eight quarters.
- The strongest year-over-year quarter for Price to Book in the past five years was Q2 2026, with growth of 258.1%; the weakest was Q4 2023, with a decline of 95.4%.
- According to Business Quant data, Price to Book for the three prior quarters was 7.10 (Q2 2026), 5.93 (Q1 2026) and 2.95 (Q4 2025).
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) |
|---|---|---|---|---|
| 1 | Eli Lilly | 1,348.13 Bn | 1,321.74 Bn | 20.46 Bn |
| 2 | Johnson & Johnson | 675.90 Bn | 595.76 Bn | 17.30 Bn |
| 3 | AbbVie | 519.45 Bn | 487.50 Bn | 13.12 Bn |
| 4 | Merck | 364.95 Bn | 327.95 Bn | 13.19 Bn |
| 5 | Novartis Ag | 311.58 Bn | 285.16 Bn | - |
| 6 | Astrazeneca | 289.34 Bn | 262.94 Bn | 13.26 Bn |
| 7 | Amgen | 251.64 Bn | 203.30 Bn | 7.58 Bn |
| 8 | Gilead Sciences | 212.05 Bn | 187.07 Bn | 6.73 Bn |
| 9 | Pfizer | 167.35 Bn | 115.00 Bn | 12.56 Bn |
| 10 | Spyre Therapeutics | 9.40 Bn | 5.68 Bn | - |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Sep 30, 2026 | 7.62 |
| Jun 30, 2026 | 7.10 |
| Mar 31, 2026 | 5.93 |
| Dec 31, 2025 | 2.95 |
| Sep 30, 2025 | 2.23 |
| Jun 30, 2025 | 1.98 |
| Mar 31, 2025 | 2.02 |
| Dec 31, 2024 | 2.13 |
| Sep 30, 2024 | 4.62 |
| Jun 30, 2024 | 3.19 |
| Mar 31, 2024 | 9.12 |
| Dec 31, 2023 | 0.86 |
| Mar 31, 2023 | 0.81 |
| Dec 31, 2022 | 0.75 |
| Sep 30, 2022 | 0.73 |
| Jun 30, 2022 | 0.49 |
| Mar 31, 2022 | 2.46 |
| Dec 31, 2021 | 3.72 |
| Sep 30, 2021 | 5.12 |
| Jun 30, 2021 | 3.84 |
API Access
Spyre Therapeutics Price to Book API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=price-to-book&ticker=SYRE&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "price-to-book", "ticker": "SYRE", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=price-to-book&ticker=SYRE&period=max&api_key=YOUR_API_KEY");
const data = await res.json();