Spyre Therapeutics (SYRE) Notes Payables (2023 - 2026)
Spyre Therapeutics (SYRE) posted Notes Payables of $50.3 million for Q1 2026, up 120.25% on a QoQ basis from $22.8 million in Q4 2025, and up 17.4% year-over-year from $42.8 million in Q1 2025.
Spyre Therapeutics (SYRE) Notes Payables (2023 - 2026) Analysis & Trends
Spyre Therapeutics' Notes Payables history runs 4 years deep, the most recent figure standing at $50.3 million for Q1 2026.
- Quarterly Notes Payables rose 17.4% year-over-year to $50.3 million in Q1 2026, while the trailing twelve-month figure through Mar 2026 was $50.3 million (up 17.4% YoY) and the FY2025 annual result came in at $22.8 million, down 9.01% from the prior year.
- Notes Payables was $50.3 million for Q1 2026 at Spyre Therapeutics, up from $22.8 million in the prior quarter.
- Across five years, Notes Payables topped out at $59.9 million in Q2 2025 and bottomed at $1.4 million in Q4 2023.
- A 4-year average of $22.6 million and a median of $21.8 million in 2023 frame the typical range for Notes Payables.
- Annual changes were most pronounced in 2024 — Notes Payables slumped 87.31% — and 2025, when it jumped 2168.94%.
- Spyre Therapeutics' Notes Payables stood at $1.4 million in 2023, then surged by 1704.32% to $25.1 million in 2024, then declined by 9.01% to $22.8 million in 2025, then jumped by 120.25% to $50.3 million in 2026.
- Business Quant data shows SYRE's Notes Payables at $50.3 million in Q1 2026, $22.8 million in Q4 2025, and $11.0 million in Q3 2025.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) |
|---|---|---|---|---|
| 1 | Oculis Holding AG | 68,785.72 Bn | 68,785.72 Bn | - |
| 2 | Nanobiotix | 1,895.57 Bn | 1,895.51 Bn | - |
| 3 | BeOne Medicines | 471.35 Bn | 466.56 Bn | 1.35 Bn |
| 4 | NuCana | 279.75 Bn | 279.75 Bn | - |
| 5 | Vertex Pharmaceuticals | 120.24 Bn | 113.00 Bn | 2.59 Bn |
| 6 | Regeneron Pharmaceuticals | 67.80 Bn | 59.04 Bn | 3.31 Bn |
| 7 | Belite Bio | 62.51 Bn | 62.51 Bn | - |
| 8 | Argenx Se | 57.38 Bn | 57.38 Bn | 1.41 Bn |
| 9 | Revolution Medicines | 37.78 Bn | 37.78 Bn | - |
| 10 | Spyre Therapeutics | 257.83 Mn | 257.83 Mn | - |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | 50.26 Mn |
| Dec 31, 2025 | 22.82 Mn |
| Sep 30, 2025 | 11.02 Mn |
| Jun 30, 2025 | 59.90 Mn |
| Mar 31, 2025 | 42.81 Mn |
| Dec 31, 2024 | 25.08 Mn |
| Sep 30, 2024 | 24.74 Mn |
| Jun 30, 2024 | 2.64 Mn |
| Mar 31, 2024 | 2.59 Mn |
| Dec 31, 2023 | 1.39 Mn |
| Sep 30, 2023 | 7.51 Mn |
| Jun 30, 2023 | 20.81 Mn |