Spyre Therapeutics (SYRE) Notes Payables (2023 - 2026)
Spyre Therapeutics' (SYRE) quarterly Notes Payables came in at $50.3 million in Q1 2026, up 17.4% YoY from $42.8 million in Q1 2025, and up 120.25% on a QoQ basis from $22.8 million in Q4 2025.
Analysis
Spyre Therapeutics (SYRE) Notes Payables (2023 - 2026) Analysis & Trends
Spyre Therapeutics (SYRE) has 4 years of Notes Payables data on file, last reported at $50.3 million in Q1 2026.
- Quarterly Notes Payables rose 17.4% year-over-year to $50.3 million in Q1 2026, while the trailing twelve-month figure through Mar 2026 was $50.3 million (up 17.4% YoY) and the FY2025 annual result came in at $22.8 million, down 9.01% from the prior year.
- Notes Payables rose to $50.3 million in Q1 2026, from $22.8 million in the prior quarter.
- In the past five years, Notes Payables ranged from a high of $59.9 million in Q2 2025 to a low of $1.4 million in Q4 2023.
- A 4-year average of $22.6 million and a median of $21.8 million in 2023 frame the typical range for Notes Payables.
- Annual changes were most pronounced in 2024 — Notes Payables tumbled 87.31% — and 2025, when it jumped 2168.94%.
- Tracing SYRE's Notes Payables over 4 years: stood at $1.4 million in 2023, then soared by 1704.32% to $25.1 million in 2024, then slipped by 9.01% to $22.8 million in 2025, then surged by 120.25% to $50.3 million in 2026.
- The last three Notes Payables figures came in at $50.3 million (Q1 2026), $22.8 million (Q4 2025), and $11.0 million (Q3 2025), per Business Quant data.
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) |
|---|---|---|---|---|
| 1 | Vertex Pharmaceuticals | 138.47 Bn | 130.62 Bn | 2.84 Bn |
| 2 | Regeneron Pharmaceuticals | 85.18 Bn | 77.19 Bn | 3.93 Bn |
| 3 | Argenx Se | 63.38 Bn | 58.19 Bn | 1.37 Bn |
| 4 | Moderna | 58.09 Bn | 52.95 Bn | 52.00 Mn |
| 5 | Revolution Medicines | 44.33 Bn | 44.33 Bn | - |
| 6 | BeOne Medicines | 40.02 Bn | 34.92 Bn | 1.53 Bn |
| 7 | Alnylam Pharmaceuticals | 35.57 Bn | 32.27 Bn | 992.69 Mn |
| 8 | Royalty Pharma | 28.45 Bn | 27.61 Bn | - |
| 9 | Insmed | 27.48 Bn | 26.32 Bn | 358.27 Mn |
| 10 | Spyre Therapeutics | 7.53 Bn | 7.53 Bn | - |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | 31.35 Mn |
| Mar 31, 2026 | 50.26 Mn |
| Dec 31, 2025 | 22.82 Mn |
| Sep 30, 2025 | 11.02 Mn |
| Jun 30, 2025 | 59.90 Mn |
| Mar 31, 2025 | 42.81 Mn |
| Dec 31, 2024 | 25.08 Mn |
| Sep 30, 2024 | 24.74 Mn |
| Jun 30, 2024 | 2.64 Mn |
| Mar 31, 2024 | 2.59 Mn |
| Dec 31, 2023 | 1.39 Mn |
| Sep 30, 2023 | 7.51 Mn |
| Jun 30, 2023 | 164.38 Mn |