Spyre Therapeutics (SYRE) Net Equity Issued and Repurchased (2015 - 2026)
Spyre Therapeutics' Net Equity Issued and Repurchased came in at $5.59 million for Q3 2026, up 819.9% from $608,000 a year earlier but down 98.8% from the prior quarter.
Powered by 
Analysis
Spyre Therapeutics (SYRE) Net Equity Issued and Repurchased (2015 - 2026) Analysis & Trends
Over the trailing twelve months to Sep 30, 2026, Spyre Therapeutics reported Net Equity Issued and Repurchased of $465.84 million; for FY2025, it came in at $3.31 million, down 56.0% from FY2024.
- Net Equity Issued and Repurchased carries a five-year compound annual growth rate of -53.6% (FY2020 to FY2025).
- Going back by year, Net Equity Issued and Repurchased was $7.51 million in FY2024 (-96.2%), $197.77 million in FY2023 (+358.9%), $43.1 million in FY2022 and $1.9 million in FY2021 (-98.8%).
- The five-year range for quarterly Net Equity Issued and Repurchased is -$167.54 million (Q4 2024) to $455.82 million (Q2 2026).
- Year-over-year, Net Equity Issued and Repurchased increased in two of the last four quarters, with growth averaging 228.5%.
- The fastest year-over-year change in Net Equity Issued and Repurchased over five years came in Q3 2026 (growth of 819.9%), and the weakest in Q1 2025 (a decline of 99.9%).
- Business Quant data shows SYRE's Net Equity Issued and Repurchased at $455.82 million (Q2 2026), $2.68 million (Q1 2026) and $1.75 million (Q4 2025) in the three quarters before Q3 2026.
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Net Equity Issued (Qtr) |
|---|---|---|---|---|---|
| 1 | Eli Lilly | 1,348.13 Bn | 1,321.74 Bn | 20.46 Bn | -377.00 Mn |
| 2 | Johnson & Johnson | 675.90 Bn | 595.76 Bn | 17.30 Bn | -966.00 Mn |
| 3 | AbbVie | 519.45 Bn | 487.50 Bn | 13.12 Bn | -5.00 Mn |
| 4 | Merck | 364.95 Bn | 327.95 Bn | 13.19 Bn | -406.00 Mn |
| 5 | Novartis Ag | 311.58 Bn | 285.16 Bn | - | - |
| 6 | Astrazeneca | 289.34 Bn | 262.94 Bn | 13.26 Bn | 4.00 Mn |
| 7 | Amgen | 251.64 Bn | 203.30 Bn | 7.58 Bn | - |
| 8 | Gilead Sciences | 212.05 Bn | 187.07 Bn | 6.73 Bn | -283.00 Mn |
| 9 | Pfizer | 167.35 Bn | 115.00 Bn | 12.56 Bn | - |
| 10 | Spyre Therapeutics | 9.40 Bn | 5.68 Bn | - | 5.59 Mn |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Sep 30, 2026 | 5.59 Mn |
| Jun 30, 2026 | 455.82 Mn |
| Mar 31, 2026 | 2.68 Mn |
| Dec 31, 2025 | 1.75 Mn |
| Sep 30, 2025 | 608,000.00 |
| Jun 30, 2025 | 731,000.00 |
| Mar 31, 2025 | 218,000.00 |
| Dec 31, 2024 | -167.54 Mn |
| Sep 30, 2024 | 878,000.00 |
| Jun 30, 2024 | 225,000.00 |
| Mar 31, 2024 | 342.80 Mn |
| Dec 31, 2023 | 282,000.00 |
| Sep 30, 2023 | -12.53 Mn |
| Jun 30, 2023 | 210.00 Mn |
| Mar 31, 2023 | 18,000.00 |
| Sep 30, 2022 | -67,000.00 |
| Jun 30, 2022 | 42.98 Mn |
| Mar 31, 2022 | 184,000.00 |
| Dec 31, 2021 | 249,000.00 |
| Sep 30, 2021 | 1.25 Mn |
API Access
Spyre Therapeutics Net Equity Issued and Repurchased API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=net-equity-issued-and-repurchased&ticker=SYRE&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "net-equity-issued-and-repurchased", "ticker": "SYRE", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=net-equity-issued-and-repurchased&ticker=SYRE&period=max&api_key=YOUR_API_KEY");
const data = await res.json();