Spyre Therapeutics (SYRE) Cash & Current Investments (2015 - 2026)
Spyre Therapeutics (SYRE) reported Cash & Current Investments of $1.15 billion for Q2 2026, up 117.5% from $526.58 million a year earlier and up 54.5% from the prior quarter.
Powered by 
Analysis
Spyre Therapeutics (SYRE) Cash & Current Investments (2015 - 2026) Analysis & Trends
At the end of FY2025, Spyre Therapeutics posted Cash & Current Investments of $756.53 million, up 25.4% from FY2024.
- Cash & Current Investments has increased for three consecutive years, with a five-year compound annual growth rate of 38.9% (FY2020 to FY2025).
- By year, Cash & Current Investments came in at $603.09 million in FY2024 (+77.8%), $339.28 million in FY2023 (+509.0%), $55.71 million in FY2022 (-40.2%) and $93.13 million in FY2021 (-36.3%).
- The Q2 2026 figure ranks as the highest quarterly Cash & Current Investments in data going back to Q1 2015.
- Year over year, Cash & Current Investments has now increased in each of the last nine quarters, with growth averaging 51.6% over the last eight quarters.
- The high point for year-over-year Cash & Current Investments in five years was Q4 2023 (growth of 509.0%); the low point was Q1 2022 (a decline of 47.3%).
- Per Business Quant data, the three quarters before Q2 2026 came in at $741.47 million (Q1 2026), $756.53 million (Q4 2025) and $486.2 million (Q3 2025).
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Cash & Current Investments (Qtr) |
|---|---|---|---|---|---|
| 1 | Eli Lilly | 1,199.50 Bn | 1,168.08 Bn | 19.71 Bn | 8.95 Bn |
| 2 | Johnson & Johnson | 635.17 Bn | 555.03 Bn | 17.30 Bn | 17.23 Bn |
| 3 | AbbVie | 504.69 Bn | 477.85 Bn | 12.70 Bn | 6.57 Bn |
| 4 | Merck | 358.43 Bn | 312.86 Bn | 12.21 Bn | 7.14 Bn |
| 5 | Novartis Ag | 288.36 Bn | 252.75 Bn | 11.24 Bn | 7.69 Bn |
| 6 | Astrazeneca | 265.78 Bn | 239.54 Bn | 12.86 Bn | 4.90 Bn |
| 7 | Amgen | 237.46 Bn | 192.86 Bn | 7.24 Bn | 13.99 Bn |
| 8 | Gilead Sciences | 193.65 Bn | 167.76 Bn | 6.22 Bn | 3.18 Bn |
| 9 | Pfizer | 171.05 Bn | 118.00 Bn | 10.94 Bn | 11.70 Bn |
| 10 | Spyre Therapeutics | 7.95 Bn | 4.83 Bn | - | 1.15 Bn |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | 1.15 Bn |
| Mar 31, 2026 | 741.47 Mn |
| Dec 31, 2025 | 756.53 Mn |
| Sep 30, 2025 | 486.20 Mn |
| Jun 30, 2025 | 526.58 Mn |
| Mar 31, 2025 | 564.82 Mn |
| Dec 31, 2024 | 603.09 Mn |
| Sep 30, 2024 | 414.23 Mn |
| Jun 30, 2024 | 426.00 Mn |
| Mar 31, 2024 | 484.64 Mn |
| Dec 31, 2023 | 339.28 Mn |
| Sep 30, 2023 | 203.60 Mn |
| Jun 30, 2023 | 235.36 Mn |
| Mar 31, 2023 | 38.48 Mn |
| Dec 31, 2022 | 55.71 Mn |
| Sep 30, 2022 | 73.68 Mn |
| Jun 30, 2022 | 88.55 Mn |
| Mar 31, 2022 | 66.73 Mn |
| Dec 31, 2021 | 93.13 Mn |
| Sep 30, 2021 | 112.43 Mn |
API Access
Spyre Therapeutics Cash & Current Investments API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=cash-and-current-investments&ticker=SYRE&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "cash-and-current-investments", "ticker": "SYRE", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=cash-and-current-investments&ticker=SYRE&period=max&api_key=YOUR_API_KEY");
const data = await res.json();