Sarepta Therapeutics (SRPT) Gross Margin (2017 - 2026)

Sarepta Therapeutics' (SRPT) quarterly Gross Margin came in at 85.12% in Q1 2026, up 8829.0% year-on-year from 0.95% in Q1 2025, and up 752.46% quarter-over-quarter from 9.98% in Q4 2025.

Sarepta Therapeutics (SRPT) Gross Margin (2017 - 2026) Analysis & Trends

Sarepta Therapeutics' Gross Margin history runs 10 years deep, the most recent figure standing at 85.12% for Q1 2026.

  • On a quarterly basis, Gross Margin rose 8829.0% year-over-year to 85.12% in Q1 2026; TTM through Mar 2026 was 62.88%, a 1208.0% decrease from a year earlier, with the FY2025 full-year figure at 54.96%, down 2826.0% from the prior year.
  • Gross Margin climbed to 85.12% in Q1 2026 per SRPT's latest filing, from 9.98% in the prior quarter.
  • Across five years, Gross Margin topped out at 96.44% in Q4 2022 and bottomed at 3.17% in Q1 2025.
  • The 5-year median for Gross Margin is 83.35% (2022), against an average of 74.43%.
  • Across the five-year window, Gross Margin tumbled 9095 bps in 2025 and jumped 8829 bps in 2026, its largest moves.
  • Year by year, Gross Margin stood at 96.44% in 2022, then slipped by 1 bps to 95.9% in 2023, then slipped by 17 bps to 79.91% in 2024, then plunged by 88 bps to 9.98% in 2025, then surged by 752 bps to 85.12% in 2026.
  • Per Business Quant, the three latest SRPT Gross Margin figures stand at 85.12% (Q1 2026), 9.98% (Q4 2025), and 62.25% (Q3 2025).

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Gross Margin (Qtr)
1 Oculis Holding AG 68,785.72 Bn 68,785.72 Bn - -
2 Nanobiotix 1,895.57 Bn 1,895.51 Bn - -
3 BeOne Medicines 471.35 Bn 466.56 Bn 1.35 Bn 88.95%
4 NuCana 279.75 Bn 279.75 Bn - -
5 Vertex Pharmaceuticals 120.24 Bn 113.00 Bn 2.59 Bn 86.85%
6 Regeneron Pharmaceuticals 67.80 Bn 59.04 Bn 3.31 Bn 91.79%
7 Belite Bio 62.51 Bn 62.51 Bn - -
8 Argenx Se 57.38 Bn 57.38 Bn 1.41 Bn 90.68%
9 Revolution Medicines 37.78 Bn 37.78 Bn - -
10 Sarepta Therapeutics 1.69 Bn 1.28 Bn 622.04 Mn 85.12%

Historic Data

Download Data
DateValue
Mar 31, 2026 85.12%
Dec 31, 2025 9.98%
Sep 30, 2025 62.25%
Jun 30, 2025 75.04%
Mar 31, 2025 -3.17%
Dec 31, 2024 79.91%
Sep 30, 2024 80.37%
Jun 30, 2024 87.73%
Mar 31, 2024 87.77%
Dec 31, 2023 95.90%
Sep 30, 2023 88.03%
Jun 30, 2023 86.94%
Mar 31, 2023 84.87%
Dec 31, 2022 96.44%
Sep 30, 2022 82.65%
Jun 30, 2022 82.11%
Mar 31, 2022 83.35%
Dec 31, 2021 82.24%
Sep 30, 2021 -4.22%
Jun 30, 2021 88.11%