Spruce Biosciences (SPRB) Return on Sales [ROS] (2023 - 2025)
Spruce Biosciences (SPRB) posted Return on Sales [ROS] of -7100.00% for Q3 2025, down 5537.21 percentage points from -1562.79% a year earlier and down 3199.62 percentage points from the prior quarter.
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Analysis
Spruce Biosciences (SPRB) Return on Sales [ROS] (2023 - 2025) Analysis & Trends
For FY2024, Spruce Biosciences' Return on Sales [ROS] came in at -1143.37%, down 628.59 percentage points from FY2023.
- In prior years, Spruce Biosciences' Return on Sales [ROS] was -514.78% in FY2023.
- The Q3 2025 figure stands as the lowest quarterly Return on Sales [ROS] in data going back to Q1 2023.
- On a year-over-year basis, Return on Sales [ROS] has declined in each of the last five quarters, with an average year-over-year change of -2046.80 percentage points over the last seven quarters.
- According to Business Quant data, Return on Sales [ROS] for the three prior quarters was -3900.38% (Q2 2025), -1994.16% (Q1 2025) and -3453.95% (Q4 2024).
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | ROS (Qtr) |
|---|---|---|---|---|---|
| 1 | Eli Lilly | 1,348.13 Bn | 1,321.74 Bn | 20.46 Bn | 34.46% |
| 2 | Johnson & Johnson | 675.90 Bn | 595.76 Bn | 17.30 Bn | 24.35% |
| 3 | AbbVie | 519.45 Bn | 487.50 Bn | 13.12 Bn | 36.01% |
| 4 | Merck | 364.95 Bn | 327.95 Bn | 13.19 Bn | 30.74% |
| 5 | Novartis Ag | 311.58 Bn | 285.16 Bn | - | - |
| 6 | Astrazeneca | 289.34 Bn | 262.94 Bn | 13.26 Bn | 29.12% |
| 7 | Amgen | 251.64 Bn | 203.30 Bn | 7.58 Bn | 35.79% |
| 8 | Gilead Sciences | 212.05 Bn | 187.07 Bn | 6.73 Bn | 41.71% |
| 9 | Pfizer | 167.35 Bn | 115.00 Bn | 12.56 Bn | 32.98% |
| 10 | Spruce Biosciences | 134.13 Mn | -152.84 Mn | - | - |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Sep 30, 2025 | -7,100.00% |
| Jun 30, 2025 | -3,900.38% |
| Mar 31, 2025 | -1,994.16% |
| Dec 31, 2024 | -3,453.95% |
| Sep 30, 2024 | -1,562.79% |
| Jun 30, 2024 | -623.35% |
| Mar 31, 2024 | -631.02% |
| Dec 31, 2023 | -385.23% |
| Sep 30, 2023 | -440.58% |
| Jun 30, 2023 | -635.09% |
| Mar 31, 2023 | -659.95% |
API Access
Spruce Biosciences Return on Sales [ROS] API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=return-on-sales-%5Bros%5D&ticker=SPRB&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "return-on-sales-[ros]", "ticker": "SPRB", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=return-on-sales-%5Bros%5D&ticker=SPRB&period=max&api_key=YOUR_API_KEY");
const data = await res.json();