Spruce Biosciences (SPRB) Return on Sales [ROS] (2023 - 2025)
Spruce Biosciences (SPRB) posted Return on Sales [ROS] of -7100.00% for Q3 2025, down 5537.21 percentage points from -1562.79% a year earlier and down 3199.62 percentage points from the prior quarter.
Powered by 
Analysis
Spruce Biosciences (SPRB) Return on Sales [ROS] (2023 - 2025) Analysis & Trends
For FY2024, Spruce Biosciences' Return on Sales [ROS] came in at -1143.37%, down 628.59 percentage points from FY2023.
- In prior years, Spruce Biosciences' Return on Sales [ROS] was -514.78% in FY2023.
- The Q3 2025 figure stands as the lowest quarterly Return on Sales [ROS] in data going back to Q1 2023.
- On a year-over-year basis, Return on Sales [ROS] has declined in each of the last five quarters, with an average year-over-year change of -2046.80 percentage points over the last seven quarters.
- According to Business Quant data, Return on Sales [ROS] for the three prior quarters was -3900.38% (Q2 2025), -1994.16% (Q1 2025) and -3453.95% (Q4 2024).
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | ROS (Qtr) |
|---|---|---|---|---|---|
| 1 | Eli Lilly | 1,076.25 Bn | 1,044.84 Bn | 19.71 Bn | 51.16% |
| 2 | Johnson & Johnson | 617.18 Bn | 535.70 Bn | 17.26 Bn | 28.21% |
| 3 | AbbVie | 464.58 Bn | 437.73 Bn | 12.70 Bn | 37.86% |
| 4 | Merck | 356.04 Bn | 310.47 Bn | 12.21 Bn | -3.52% |
| 5 | Novartis Ag | 269.07 Bn | 224.94 Bn | 11.24 Bn | 32.97% |
| 6 | Astrazeneca | 243.21 Bn | 216.77 Bn | 12.86 Bn | 20.57% |
| 7 | Amgen | 217.88 Bn | 173.28 Bn | 7.24 Bn | 34.95% |
| 8 | Gilead Sciences | 179.62 Bn | 153.74 Bn | 6.22 Bn | -133.21% |
| 9 | Pfizer | 158.45 Bn | 105.40 Bn | 10.94 Bn | 28.37% |
| 10 | Spruce Biosciences | 125.83 Mn | 125.83 Mn | - | - |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Sep 30, 2025 | -7,100.00% |
| Jun 30, 2025 | -3,900.38% |
| Mar 31, 2025 | -1,994.16% |
| Dec 31, 2024 | -3,453.95% |
| Sep 30, 2024 | -1,562.79% |
| Jun 30, 2024 | -623.35% |
| Mar 31, 2024 | -631.02% |
| Dec 31, 2023 | -385.23% |
| Sep 30, 2023 | -440.58% |
| Jun 30, 2023 | -635.09% |
| Mar 31, 2023 | -659.95% |
API Access
Spruce Biosciences Return on Sales [ROS] API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=return-on-sales-%5Bros%5D&ticker=SPRB&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "return-on-sales-[ros]", "ticker": "SPRB", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=return-on-sales-%5Bros%5D&ticker=SPRB&period=max&api_key=YOUR_API_KEY");
const data = await res.json();