Spruce Biosciences (SPRB) Return on Sales (2023 - 2025)
Spruce Biosciences (SPRB) posted quarterly Return on Sales of 0.69% for Q3 2025, down 54.0% year-over-year from 1.5% in Q3 2024, and down 84.32% quarter-over-quarter from 0.37% in Q2 2025.
Spruce Biosciences (SPRB) Return on Sales (2023 - 2025) Analysis & Trends
Spruce Biosciences (SPRB) has reported Return on Sales for 3 consecutive years, with 0.69% the latest figure, recorded in Q3 2025.
- In Q3 2025, Return on Sales fell 54.0% year-over-year to 0.69%; the TTM figure through Sep 2025 stood at 0.69% (down 63.0% YoY), while the FY2024 annual figure was 0.11%, down 5.0% from the prior year.
- Return on Sales declined to 0.69% in Q3 2025 per SPRB's latest filing, from 0.37% in the prior quarter.
- Across five years, Return on Sales topped out at 0.04% in Q4 2023 and bottomed at 0.69% in Q3 2025.
- Historically, Return on Sales has averaged 0.19% across 3 years, with a median of 0.07% in 2023.
- Annual changes were most pronounced in 2024 — Return on Sales rose 1 bps — and 2025, when it plunged 54 bps.
- Spruce Biosciences' Return on Sales stood at 0.04% in 2023, then slumped by 767 bps to 0.34% in 2024, then tumbled by 104 bps to 0.69% in 2025.
- Business Quant data shows SPRB's Return on Sales at 0.69% in Q3 2025, 0.37% in Q2 2025, and 0.19% in Q1 2025.
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Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | ROS (Qtr) |
|---|---|---|---|---|---|
| 1 | Vertex Pharmaceuticals | 140.52 Bn | 132.67 Bn | 2.84 Bn | 0.00% |
| 2 | Regeneron Pharmaceuticals | 86.54 Bn | 78.55 Bn | 3.93 Bn | 0.00% |
| 3 | Argenx Se | 65.31 Bn | 60.13 Bn | 1.37 Bn | 0.00% |
| 4 | Moderna | 61.77 Bn | 56.64 Bn | 52.00 Mn | -0.05% |
| 5 | BeOne Medicines | 42.26 Bn | 37.16 Bn | 1.53 Bn | 0.00% |
| 6 | Alnylam Pharmaceuticals | 31.19 Bn | 27.88 Bn | 992.69 Mn | 0.00% |
| 7 | BioNTech SE | 28.71 Bn | 10.31 Bn | 668.28 Mn | 0.00% |
| 8 | Insmed | 27.48 Bn | 26.32 Bn | 358.27 Mn | 0.00% |
| 9 | Royalty Pharma | 27.35 Bn | 26.52 Bn | - | 0.00% |
| 10 | Spruce Biosciences | 127.00 Mn | 127.00 Mn | - | - |
Historic Data
Download Data| Date | Value |
|---|---|
| Sep 30, 2025 | -0.69% |
| Jun 30, 2025 | -0.37% |
| Mar 31, 2025 | -0.19% |
| Dec 31, 2024 | -0.34% |
| Sep 30, 2024 | -0.14% |
| Jun 30, 2024 | -0.06% |
| Mar 31, 2024 | -0.06% |
| Dec 31, 2023 | -0.04% |
| Sep 30, 2023 | -0.04% |
| Jun 30, 2023 | -0.06% |
| Mar 31, 2023 | -0.07% |