Spruce Biosciences SPRB
NASDAQ SPRB
$51.40 -0.58 (-1.13%)
As of: Aug 21, 2026 · 10:46 AM EDT

Spruce Biosciences (SPRB) Return on Capital Employed (2020 - 2026)

Spruce Biosciences (SPRB) posted quarterly Return on Capital Employed of 79.44% for Q1 2026, up 17540.0% year-over-year from N/an in Q1 2025, and up 47.61% quarter-over-quarter from 151.63% in Q4 2025.

Spruce Biosciences (SPRB) Return on Capital Employed (2020 - 2026) Analysis & Trends

Spruce Biosciences (SPRB) has reported Return on Capital Employed for 7 consecutive years, with 79.44% the latest figure, recorded in Q1 2026.

  • In Q1 2026, Return on Capital Employed rose 17540.0% year-over-year to 79.44%; the TTM figure through Mar 2026 stood at 79.44% (up 17540.0% YoY), while the FY2025 annual figure was 93.55%, up 109.0% from the prior year.
  • Return on Capital Employed grew to 79.44% in Q1 2026 per SPRB's latest filing, from 151.63% in the prior quarter.
  • Across five years, Return on Capital Employed topped out at 39.35% in Q1 2022 and bottomed at 541.46% in Q3 2025.
  • Historically, Return on Capital Employed has averaged 121.38% across 5 years, with a median of 66.49% in 2024.
  • Annual changes were most pronounced in 2025 — Return on Capital Employed tumbled 46749 bps — and 2026, when it surged 17540 bps.
  • Spruce Biosciences' Return on Capital Employed stood at 60.6% in 2022, then retreated by 2 bps to 61.9% in 2023, then tumbled by 127 bps to 140.7% in 2024, then slipped by 8 bps to 151.63% in 2025, then soared by 48 bps to 79.44% in 2026.
  • Business Quant data shows SPRB's Return on Capital Employed at 79.44% in Q1 2026, 151.63% in Q4 2025, and 541.46% in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) ROCE (Qtr)
1 Vertex Pharmaceuticals 139.96 Bn 132.11 Bn 2.84 Bn 20.76%
2 Regeneron Pharmaceuticals 86.79 Bn 78.79 Bn 3.93 Bn 10.74%
3 Argenx Se 65.22 Bn 60.03 Bn 1.37 Bn -
4 Moderna 60.20 Bn 55.06 Bn 52.00 Mn -38.20%
5 BeOne Medicines 42.19 Bn 37.09 Bn 1.53 Bn 13.68%
6 Alnylam Pharmaceuticals 31.43 Bn 28.12 Bn 992.69 Mn 26.09%
7 BioNTech SE 28.65 Bn 10.26 Bn 668.28 Mn -6.85%
8 Insmed 27.48 Bn 26.32 Bn 358.27 Mn -50.93%
9 Royalty Pharma 27.16 Bn 26.32 Bn - 7.88%
10 Spruce Biosciences 124.96 Mn 124.96 Mn - -69.78%

Historic Data

Download Data
DateValue
Jun 30, 2026 -69.78%
Mar 31, 2026 -79.44%
Dec 31, 2025 -151.63%
Sep 30, 2025 -541.46%
Jun 30, 2025 -271.31%
Mar 31, 2025 -254.84%
Dec 31, 2024 -140.70%
Sep 30, 2024 -73.98%
Jun 30, 2024 -70.62%
Mar 31, 2024 -66.49%
Dec 31, 2023 -61.90%
Sep 30, 2023 -55.56%
Jun 30, 2023 -46.30%
Mar 31, 2023 -54.54%
Dec 31, 2022 -60.60%
Sep 30, 2022 -50.40%
Jun 30, 2022 -44.31%
Mar 31, 2022 -39.35%
Dec 31, 2021 -34.50%
Sep 30, 2021 -31.69%