Spruce Biosciences SPRB
NASDAQ SPRB
$51.99 -0.97 (-1.83%)
At close: Aug 20, 2026 · 4:00 PM EDT

Spruce Biosciences (SPRB) Net Margin (2023 - 2024)

Spruce Biosciences (SPRB) posted quarterly Net Margin of 3368.29% for Q4 2024, down 297978.0% year-over-year from N/an in Q1 2024, and down 133.07% quarter-over-quarter from 1445.17% in Q3 2024.

Spruce Biosciences (SPRB) Net Margin (2023 - 2024) Analysis & Trends

Spruce Biosciences (SPRB) has reported Net Margin for 2 consecutive years, with 3368.29% the latest figure, recorded in Q4 2024.

  • In Q4 2024, Net Margin fell 297978.0% year-over-year to 3368.29%; the TTM figure through Sep 2025 stood at 6880.2% (down 630715.0% YoY), while the FY2024 annual figure was 1080.7%, down 54124.0% from the prior year.
  • Net Margin slipped to 3368.29% in Q4 2024 per SPRB's latest filing, from 1445.17% in the prior quarter.
  • Across five years, Net Margin topped out at 388.52% in Q4 2023 and bottomed at 3368.29% in Q4 2024.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Net Margin (Qtr)
1 Vertex Pharmaceuticals 137.11 Bn 129.26 Bn 2.84 Bn 32.99%
2 Regeneron Pharmaceuticals 84.98 Bn 76.99 Bn 3.93 Bn 30.23%
3 Argenx Se 64.52 Bn 59.33 Bn 1.37 Bn 31.16%
4 Moderna 53.23 Bn 48.09 Bn 52.00 Mn -539.31%
5 BeOne Medicines 41.23 Bn 36.14 Bn 1.53 Bn 13.90%
6 Alnylam Pharmaceuticals 30.65 Bn 27.34 Bn 992.69 Mn 12.74%
7 Insmed 27.15 Bn 25.99 Bn 358.27 Mn -3.12%
8 Royalty Pharma 26.98 Bn 26.14 Bn - 12.09%
9 BioNTech SE 26.78 Bn 8.39 Bn 668.28 Mn -16.51%
10 Spruce Biosciences 127.07 Mn 127.07 Mn - -

Historic Data

Download Data
DateValue
Dec 31, 2024 -3,368.29%
Sep 30, 2024 -1,445.17%
Jun 30, 2024 -570.25%
Mar 31, 2024 -581.25%
Dec 31, 2023 -388.52%
Sep 30, 2023 -446.63%
Jun 30, 2023 -634.82%
Mar 31, 2023 -652.40%