Spruce Biosciences SPRB
NASDAQ SPRB
$51.80 -0.19 (-0.36%)
As of: Aug 21, 2026 · 9:35 AM EDT

Spruce Biosciences (SPRB) Net Cash Flow (2019 - 2026)

Spruce Biosciences (SPRB) posted quarterly Net Cash Flow of $5.2 million for Q1 2026, up 139.38% year-over-year from $2.2 million in Q1 2025, and down 89.87% quarter-over-quarter from $51.1 million in Q4 2025.

Spruce Biosciences (SPRB) Net Cash Flow (2019 - 2026) Analysis & Trends

Spruce Biosciences (SPRB) has reported Net Cash Flow for 8 consecutive years, with $5.2 million the latest figure, recorded in Q1 2026.

  • In Q1 2026, Net Cash Flow rose 139.38% year-over-year to $5.2 million; the TTM figure through Mar 2026 stood at $95.1 million (up 271.22% YoY), while the FY2025 annual figure was $76.8 million, up 233.33% from the prior year.
  • Net Cash Flow declined to $5.2 million in Q1 2026 per SPRB's latest filing, from $51.1 million in the prior quarter.
  • Across five years, Net Cash Flow topped out at $51.1 million in Q4 2025 and bottomed at -$25.6 million in Q3 2022.
  • Historically, Net Cash Flow has averaged $4.6 million across 5 years, with a median of -$2.5 million in 2023.
  • Annual changes were most pronounced in 2024 — Net Cash Flow sank 829.95% — and 2025, when it jumped 599.1%.
  • Spruce Biosciences' Net Cash Flow stood at $2.9 million in 2022, then tumbled by 185.84% to -$2.5 million in 2023, then sank by 765.58% to -$21.3 million in 2024, then soared by 339.86% to $51.1 million in 2025, then plunged by 89.87% to $5.2 million in 2026.
  • Business Quant data shows SPRB's Net Cash Flow at $5.2 million in Q1 2026, $51.1 million in Q4 2025, and $48.1 million in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Net Cash Flow (Qtr)
1 Vertex Pharmaceuticals 138.04 Bn 130.19 Bn 2.84 Bn 652.90 Mn
2 Regeneron Pharmaceuticals 85.58 Bn 77.59 Bn 3.93 Bn -504.30 Mn
3 Argenx Se 64.52 Bn 59.34 Bn 1.37 Bn -
4 Moderna 56.52 Bn 51.38 Bn 52.00 Mn -183.00 Mn
5 BeOne Medicines 42.04 Bn 36.94 Bn 1.53 Bn 407.41 Mn
6 Alnylam Pharmaceuticals 30.67 Bn 27.36 Bn 992.69 Mn -496,000.00
7 Insmed 27.27 Bn 26.11 Bn 358.27 Mn -37.14 Mn
8 BioNTech SE 27.14 Bn 8.75 Bn 668.28 Mn -2.83 Bn
9 Royalty Pharma 27.12 Bn 26.28 Bn - 225.59 Mn
10 Spruce Biosciences 127.58 Mn 127.58 Mn - 103.97 Mn

Historic Data

Download Data
DateValue
Jun 30, 2026 103.97 Mn
Jun 30, 2026 103.97 Mn
Mar 31, 2026 5.17 Mn
Mar 31, 2026 5.17 Mn
Dec 31, 2025 51.09 Mn
Dec 31, 2025 51.09 Mn
Sep 30, 2025 48.05 Mn
Sep 30, 2025 48.05 Mn
Jun 30, 2025 -9.23 Mn
Jun 30, 2025 -9.23 Mn
Mar 31, 2025 -13.14 Mn
Mar 31, 2025 -13.14 Mn
Dec 31, 2024 -21.30 Mn
Dec 31, 2024 -21.30 Mn
Sep 30, 2024 -9.63 Mn
Sep 30, 2024 -9.63 Mn
Jun 30, 2024 -11.47 Mn
Jun 30, 2024 -11.47 Mn
Mar 31, 2024 -15.19 Mn
Mar 31, 2024 -15.19 Mn