Vertex Pharmaceuticals (VRTX) Net Cash Flow (2009 - 2026)
Vertex Pharmaceuticals' quarterly Net Cash Flow came in at $457.4 million in Q1 2026, up 453.08% year-on-year from $82.7 million in Q1 2025, and up 244.69% quarter-over-quarter from $132.7 million in Q4 2025.
Vertex Pharmaceuticals has reported Net Cash Flow for 18 years, with the latest figure at $457.4 million in Q1 2026.
- For the quarter ending Q1 2026, Net Cash Flow rose 453.08% year-over-year to $457.4 million; the trailing twelve-month figure through Mar 2026 stood at $799.4 million (up 117.81% YoY), and the FY2025 full-year result was $424.7 million, up 107.38% from the prior year.
- Net Cash Flow for Q1 2026 stood at $457.4 million, up from $132.7 million in the prior quarter.
- The five-year high for Net Cash Flow was $1.3 billion in Q4 2022, with the low at -$4.6 billion in Q2 2024.
- Average Net Cash Flow over 5 years is -$76.5 million, with a median of $239.4 million recorded in 2025.
- Year-over-year, Net Cash Flow jumped 558.1% in 2022 and slumped 639.74% in 2024.
- Tracing VRTX's Net Cash Flow over 5 years: stood at $1.3 billion in 2022, then slumped by 159.63% to -$771.7 million in 2023, then grew by 18.54% to -$628.6 million in 2024, then jumped by 121.11% to $132.7 million in 2025, then surged by 244.69% to $457.4 million in 2026.
- The last three Net Cash Flow figures came in at $457.4 million (Q1 2026), $132.7 million (Q4 2025), and -$30.1 million (Q3 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Net Cash Flow (Qtr) |
|---|---|---|---|---|---|
| 1 | Quantum Biopharma | 961,148.99 Bn | 961,148.98 Bn | - | 2.44 Mn |
| 2 | Alterity Therapeutics | 744,933.29 Bn | 744,933.26 Bn | - | - |
| 3 | Legend Biotech | 2,540.00 Bn | 2,539.71 Bn | 242.10 Mn | 625.70 Mn |
| 4 | Nanobiotix | 2,199.85 Bn | 2,199.78 Bn | - | - |
| 5 | Akari Therapeutics | 1,635.88 Bn | 1,635.88 Bn | - | -2.44 Mn |
| 6 | Vertex Pharmaceuticals | 111.32 Bn | 104.07 Bn | 2.59 Bn | 457.40 Mn |
| 7 | Evaxion A | 62.56 Bn | 62.54 Bn | - | - |
| 8 | Regeneron Pharmaceuticals | 62.55 Bn | 53.79 Bn | 3.31 Bn | -152.20 Mn |
| 9 | Alnylam Pharmaceuticals | 39.57 Bn | 36.56 Bn | 959.66 Mn | 60.68 Mn |
| 10 | Revolution Medicines | 32.39 Bn | 32.39 Bn | - | 57.19 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | 457.40 Mn |
| Mar 31, 2026 | 457.40 Mn |
| Dec 31, 2025 | 132.70 Mn |
| Dec 31, 2025 | 132.70 Mn |
| Sep 30, 2025 | -30.10 Mn |
| Sep 30, 2025 | -30.10 Mn |
| Jun 30, 2025 | 239.40 Mn |
| Jun 30, 2025 | 239.40 Mn |
| Mar 31, 2025 | 82.70 Mn |
| Mar 31, 2025 | 82.70 Mn |
| Dec 31, 2024 | -628.60 Mn |
| Dec 31, 2024 | -628.60 Mn |
| Sep 30, 2024 | 634.30 Mn |
| Sep 30, 2024 | 634.30 Mn |
| Jun 30, 2024 | -4.58 Bn |
| Jun 30, 2024 | -4.58 Bn |
| Mar 31, 2024 | -1.19 Bn |
| Mar 31, 2024 | -1.19 Bn |
| Dec 31, 2023 | -771.70 Mn |
| Dec 31, 2023 | -771.70 Mn |
| Sep 30, 2023 | 985.70 Mn |
| Sep 30, 2023 | 985.70 Mn |
| Jun 30, 2023 | 847.80 Mn |
| Jun 30, 2023 | 847.80 Mn |
| Mar 31, 2023 | -1.23 Bn |
| Mar 31, 2023 | -1.23 Bn |
| Dec 31, 2022 | 1.29 Bn |
| Dec 31, 2022 | 1.29 Bn |
| Sep 30, 2022 | 511.10 Mn |
| Sep 30, 2022 | 511.10 Mn |
| Jun 30, 2022 | 1.13 Bn |
| Jun 30, 2022 | 1.13 Bn |
| Mar 31, 2022 | 809.80 Mn |
| Mar 31, 2022 | 809.80 Mn |
| Dec 31, 2021 | 524.80 Mn |
| Dec 31, 2021 | 524.80 Mn |
| Sep 30, 2021 | 217.60 Mn |
| Sep 30, 2021 | 217.60 Mn |
| Jun 30, 2021 | -245.80 Mn |
| Jun 30, 2021 | -245.80 Mn |
| Mar 31, 2021 | 328.00 Mn |
| Mar 31, 2021 | 328.00 Mn |
| Dec 31, 2020 | 610.08 Mn |
| Dec 31, 2020 | 610.08 Mn |
| Sep 30, 2020 | 519.13 Mn |
| Sep 30, 2020 | 519.13 Mn |
| Jun 30, 2020 | 1.23 Bn |
| Jun 30, 2020 | 1.23 Bn |
| Mar 31, 2020 | 487.93 Mn |
| Mar 31, 2020 | 487.93 Mn |
| Dec 31, 2019 | -289.55 Mn |
| Dec 31, 2019 | -289.55 Mn |
| Sep 30, 2019 | 106.15 Mn |
| Sep 30, 2019 | 106.15 Mn |
| Jun 30, 2019 | 400.54 Mn |
| Jun 30, 2019 | 400.54 Mn |
| Mar 31, 2019 | 243.66 Mn |
| Mar 31, 2019 | 243.66 Mn |
| Dec 31, 2018 | 172.63 Mn |
| Dec 31, 2018 | 172.63 Mn |
| Sep 30, 2018 | 333.54 Mn |
| Sep 30, 2018 | 333.54 Mn |
| Jun 30, 2018 | 154.20 Mn |
| Jun 30, 2018 | 154.20 Mn |
| Mar 31, 2018 | 336.55 Mn |
| Mar 31, 2018 | 336.55 Mn |
| Dec 31, 2017 | 279.96 Mn |
| Dec 31, 2017 | 279.96 Mn |
| Sep 30, 2017 | 97.51 Mn |
| Sep 30, 2017 | 97.51 Mn |
| Jun 30, 2017 | 237.40 Mn |
| Jun 30, 2017 | 237.40 Mn |
| Mar 31, 2017 | -184.85 Mn |
| Mar 31, 2017 | -184.85 Mn |
| Dec 31, 2016 | 415.42 Mn |
| Dec 31, 2016 | 415.42 Mn |
| Sep 30, 2016 | 114.00 Mn |
| Sep 30, 2016 | 114.00 Mn |
| Jun 30, 2016 | 4.33 Mn |
| Jun 30, 2016 | 4.33 Mn |
| Mar 31, 2016 | -113.14 Mn |
| Mar 31, 2016 | -113.14 Mn |
| Dec 31, 2015 | -40.91 Mn |
| Dec 31, 2015 | -40.91 Mn |
| Sep 30, 2015 | -113.34 Mn |
| Sep 30, 2015 | -113.34 Mn |
| Jun 30, 2015 | 204.37 Mn |
| Jun 30, 2015 | 204.37 Mn |
| Mar 31, 2015 | 42.22 Mn |
| Mar 31, 2015 | 42.22 Mn |
| Dec 31, 2014 | -91.61 Mn |
| Dec 31, 2014 | -91.61 Mn |
| Sep 30, 2014 | 300.13 Mn |
| Sep 30, 2014 | 300.13 Mn |
| Jun 30, 2014 | -4.63 Mn |
| Jun 30, 2014 | -4.63 Mn |
| Mar 31, 2014 | -145.75 Mn |
| Mar 31, 2014 | -145.75 Mn |
| Dec 31, 2013 | -16.00 Mn |
| Dec 31, 2013 | -16.00 Mn |
| Sep 30, 2013 | 48.82 Mn |
| Sep 30, 2013 | 48.82 Mn |
| Jun 30, 2013 | 151.87 Mn |
| Jun 30, 2013 | 151.87 Mn |
| Mar 31, 2013 | -109.51 Mn |
| Mar 31, 2013 | -109.51 Mn |
| Dec 31, 2012 | 52.55 Mn |
| Dec 31, 2012 | 52.55 Mn |
| Sep 30, 2012 | -17.12 Mn |
| Sep 30, 2012 | -17.12 Mn |
| Jun 30, 2012 | 186.05 Mn |
| Jun 30, 2012 | 186.05 Mn |
| Mar 31, 2012 | -207.26 Mn |
| Mar 31, 2012 | -207.26 Mn |
| Dec 31, 2011 | -67.09 Mn |
| Dec 31, 2011 | -67.09 Mn |
| Sep 30, 2011 | 84.41 Mn |
| Sep 30, 2011 | 84.41 Mn |
| Mar 31, 2011 | 202.97 Mn |
| Mar 31, 2011 | 202.97 Mn |
| Dec 31, 2010 | -326.35 Mn |
| Dec 31, 2010 | -326.35 Mn |
| Sep 30, 2010 | 232.09 Mn |
| Sep 30, 2010 | 232.09 Mn |
| Jun 30, 2010 | -58.77 Mn |
| Jun 30, 2010 | -58.77 Mn |
| Mar 31, 2010 | -50.06 Mn |
| Mar 31, 2010 | -50.06 Mn |
| Dec 31, 2009 | -111.44 Mn |
| Dec 31, 2009 | -111.44 Mn |
| Sep 30, 2009 | 151.48 Mn |
| Sep 30, 2009 | 151.48 Mn |
| Jun 30, 2009 | -190.64 Mn |
| Jun 30, 2009 | -190.64 Mn |
| Mar 31, 2009 | 213.29 Mn |
| Mar 31, 2009 | 213.29 Mn |