Vertex Pharmaceuticals (VRTX) Net Cash Flow (2009 - 2026)

Vertex Pharmaceuticals' (VRTX) quarterly Net Cash Flow came in at $457.4 million in Q1 2026, up 453.08% year-on-year from $82.7 million in Q1 2025, and up 244.69% quarter-over-quarter from $132.7 million in Q4 2025.

Vertex Pharmaceuticals (VRTX) Net Cash Flow (2009 - 2026) Analysis & Trends

Vertex Pharmaceuticals' Net Cash Flow history runs 18 years deep, the most recent figure standing at $457.4 million for Q1 2026.

  • On a quarterly basis, Net Cash Flow rose 453.08% year-over-year to $457.4 million in Q1 2026; TTM through Mar 2026 was $799.4 million, a 117.81% increase from a year earlier, with the FY2025 full-year figure at $424.7 million, up 107.38% from the prior year.
  • Net Cash Flow climbed to $457.4 million in Q1 2026 per VRTX's latest filing, from $132.7 million in the prior quarter.
  • Across five years, Net Cash Flow topped out at $1.3 billion in Q4 2022 and bottomed at -$4.6 billion in Q2 2024.
  • The 5-year median for Net Cash Flow is $239.4 million (2025), against an average of -$76.5 million.
  • Across the five-year window, Net Cash Flow surged 558.1% in 2022 and slumped 639.74% in 2024, its largest moves.
  • Year by year, Net Cash Flow stood at $1.3 billion in 2022, then sank by 159.63% to -$771.7 million in 2023, then climbed by 18.54% to -$628.6 million in 2024, then soared by 121.11% to $132.7 million in 2025, then jumped by 244.69% to $457.4 million in 2026.
  • Per Business Quant, the three latest VRTX Net Cash Flow figures stand at $457.4 million (Q1 2026), $132.7 million (Q4 2025), and -$30.1 million (Q3 2025).

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Net Cash Flow (Qtr)
1 Oculis Holding AG 67,072.09 Bn 67,072.09 Bn - 10.56 Mn
2 Nanobiotix 1,894.61 Bn 1,894.55 Bn - -
3 Akari Therapeutics 1,014.18 Bn 1,014.18 Bn - -2.44 Mn
4 BeOne Medicines 471.64 Bn 466.85 Bn 1.35 Bn 224.46 Mn
5 Vertex Pharmaceuticals 121.72 Bn 114.47 Bn 2.59 Bn 457.40 Mn
6 Regeneron Pharmaceuticals 68.28 Bn 59.52 Bn 3.31 Bn -152.20 Mn
7 Belite Bio 61.40 Bn 61.40 Bn - -
8 Argenx Se 56.94 Bn 56.94 Bn 1.18 Bn -
9 Revolution Medicines 37.37 Bn 37.37 Bn - 57.19 Mn
10 Alnylam Pharmaceuticals 36.08 Bn 33.07 Bn 959.66 Mn 60.68 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 457.40 Mn
Mar 31, 2026 457.40 Mn
Dec 31, 2025 132.70 Mn
Dec 31, 2025 132.70 Mn
Sep 30, 2025 -30.10 Mn
Sep 30, 2025 -30.10 Mn
Jun 30, 2025 239.40 Mn
Jun 30, 2025 239.40 Mn
Mar 31, 2025 82.70 Mn
Mar 31, 2025 82.70 Mn
Dec 31, 2024 -628.60 Mn
Dec 31, 2024 -628.60 Mn
Sep 30, 2024 634.30 Mn
Sep 30, 2024 634.30 Mn
Jun 30, 2024 -4.58 Bn
Jun 30, 2024 -4.58 Bn
Mar 31, 2024 -1.19 Bn
Mar 31, 2024 -1.19 Bn
Dec 31, 2023 -771.70 Mn
Dec 31, 2023 -771.70 Mn