Vertex Pharmaceuticals (VRTX) Net Cash Flow (2009 - 2026)

Vertex Pharmaceuticals (VRTX) recorded quarterly Net Cash Flow of $457.4 million in Q1 2026, up 244.69% quarter-over-quarter from $132.7 million in Q4 2025, and up 453.08% on a YoY basis from $82.7 million in Q1 2025.

Vertex Pharmaceuticals (VRTX) Net Cash Flow (2009 - 2026) Analysis & Trends

Vertex Pharmaceuticals' Net Cash Flow history runs 18 years deep, the most recent figure standing at $457.4 million for Q1 2026.

  • In Q1 2026, Net Cash Flow rose 453.08% year-over-year to $457.4 million; the TTM figure through Mar 2026 stood at $799.4 million (up 117.81% YoY), while the FY2025 annual figure was $424.7 million, up 107.38% from the prior year.
  • Net Cash Flow was $457.4 million for Q1 2026 at Vertex Pharmaceuticals, up from $132.7 million in the prior quarter.
  • In the past five years, Net Cash Flow ranged from a high of $1.3 billion in Q4 2022 to a low of -$4.6 billion in Q2 2024.
  • Historically, Net Cash Flow has averaged -$76.5 million across 5 years, with a median of $239.4 million in 2025.
  • The sharpest annual moves came in 2022 and 2024: Net Cash Flow surged 558.1% in 2022, then slumped 639.74% in 2024.
  • A 5-year view of Net Cash Flow shows it stood at $1.3 billion in 2022, then tumbled by 159.63% to -$771.7 million in 2023, then climbed by 18.54% to -$628.6 million in 2024, then soared by 121.11% to $132.7 million in 2025, then jumped by 244.69% to $457.4 million in 2026.
  • The last three Net Cash Flow figures came in at $457.4 million (Q1 2026), $132.7 million (Q4 2025), and -$30.1 million (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Net Cash Flow (Qtr)
1 Alterity Therapeutics 925,601.88 Bn 925,601.85 Bn - -
2 Belite Bio 58,560.00 Bn 58,560.00 Bn - -
3 Quantum Biopharma 17,284.41 Bn 17,284.40 Bn - 2.44 Mn
4 Legend Biotech 2,809.00 Bn 2,808.71 Bn 242.10 Mn 625.70 Mn
5 Evaxion A 1,334.43 Bn 1,334.42 Bn - -
6 Akari Therapeutics 1,312.27 Bn 1,312.26 Bn - -2.44 Mn
7 Psyence Biomedical 212.16 Bn 212.16 Bn - -
8 Vertex Pharmaceuticals 114.83 Bn 107.58 Bn 2.59 Bn 457.40 Mn
9 Abivax 91.96 Bn 91.96 Bn - 664,983.53
10 Regeneron Pharmaceuticals 63.43 Bn 54.67 Bn 3.31 Bn -152.20 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 457.40 Mn
Mar 31, 2026 457.40 Mn
Dec 31, 2025 132.70 Mn
Dec 31, 2025 132.70 Mn
Sep 30, 2025 -30.10 Mn
Sep 30, 2025 -30.10 Mn
Jun 30, 2025 239.40 Mn
Jun 30, 2025 239.40 Mn
Mar 31, 2025 82.70 Mn
Mar 31, 2025 82.70 Mn
Dec 31, 2024 -628.60 Mn
Dec 31, 2024 -628.60 Mn
Sep 30, 2024 634.30 Mn
Sep 30, 2024 634.30 Mn
Jun 30, 2024 -4.58 Bn
Jun 30, 2024 -4.58 Bn
Mar 31, 2024 -1.19 Bn
Mar 31, 2024 -1.19 Bn
Dec 31, 2023 -771.70 Mn
Dec 31, 2023 -771.70 Mn