Vertex Pharmaceuticals (VRTX) Net Cash Flow (2009 - 2026)

Vertex Pharmaceuticals (VRTX) posted quarterly Net Cash Flow of $457.4 million for Q1 2026, up 453.08% year-over-year from $82.7 million in Q1 2025, and up 244.69% quarter-over-quarter from $132.7 million in Q4 2025.

Vertex Pharmaceuticals (VRTX) Net Cash Flow (2009 - 2026) Analysis & Trends

Vertex Pharmaceuticals' Net Cash Flow history runs 18 years deep, the most recent figure standing at $457.4 million for Q1 2026.

  • In Q1 2026, Net Cash Flow rose 453.08% year-over-year to $457.4 million; the TTM figure through Mar 2026 stood at $799.4 million (up 117.81% YoY), while the FY2025 annual figure was $424.7 million, up 107.38% from the prior year.
  • Net Cash Flow for Q1 2026 stood at $457.4 million, up from $132.7 million in the prior quarter.
  • The five-year high for Net Cash Flow was $1.3 billion in Q4 2022, with the low at -$4.6 billion in Q2 2024.
  • The 5-year median for Net Cash Flow is $239.4 million (2025), against an average of -$76.5 million.
  • The sharpest annual moves came in 2022 and 2024: Net Cash Flow surged 558.1% in 2022, then sank 639.74% in 2024.
  • Vertex Pharmaceuticals' Net Cash Flow stood at $1.3 billion in 2022, then slumped by 159.63% to -$771.7 million in 2023, then advanced by 18.54% to -$628.6 million in 2024, then surged by 121.11% to $132.7 million in 2025, then soared by 244.69% to $457.4 million in 2026.
  • Business Quant data shows VRTX's Net Cash Flow at $457.4 million in Q1 2026, $132.7 million in Q4 2025, and -$30.1 million in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Net Cash Flow (Qtr)
1 Vertex Pharmaceuticals 128.13 Bn 120.28 Bn 2.84 Bn 652.90 Mn
2 Regeneron Pharmaceuticals 112.33 Bn 104.33 Bn 3.93 Bn -504.30 Mn
3 Argenx Se 53.24 Bn 48.05 Bn 1.41 Bn -
4 Revolution Medicines 43.64 Bn 43.64 Bn - 374.50 Mn
5 BeOne Medicines 39.27 Bn 34.17 Bn 1.53 Bn 407.41 Mn
6 MindWalk Holdings 35.32 Bn 35.31 Bn 1.82 Bn 17.81 Mn
7 Royalty Pharma 33.72 Bn 35.84 Bn - 225.59 Mn
8 Alnylam Pharmaceuticals 30.58 Bn 27.27 Bn 992.69 Mn -496,000.00
9 Insmed 27.01 Bn 25.85 Bn 358.27 Mn -37.14 Mn
10 Roivant Sciences 26.16 Bn 26.85 Bn 1.16 Mn -170.75 Mn

Historic Data

Download Data
DateValue
Jun 30, 2026 652.90 Mn
Jun 30, 2026 652.90 Mn
Mar 31, 2026 457.40 Mn
Mar 31, 2026 457.40 Mn
Dec 31, 2025 132.70 Mn
Dec 31, 2025 132.70 Mn
Sep 30, 2025 -30.10 Mn
Sep 30, 2025 -30.10 Mn
Jun 30, 2025 239.40 Mn
Jun 30, 2025 239.40 Mn
Mar 31, 2025 82.70 Mn
Mar 31, 2025 82.70 Mn
Dec 31, 2024 -628.60 Mn
Dec 31, 2024 -628.60 Mn
Sep 30, 2024 634.30 Mn
Sep 30, 2024 634.30 Mn
Jun 30, 2024 -4.58 Bn
Jun 30, 2024 -4.58 Bn
Mar 31, 2024 -1.19 Bn
Mar 31, 2024 -1.19 Bn