Spruce Biosciences SPRB
NASDAQ SPRB
$51.58 -0.40 (-0.78%)
At close: Aug 21, 2026 · 4:00 PM EDT

Spruce Biosciences (SPRB) Free Cash Flow (2019 - 2026)

Spruce Biosciences (SPRB) posted quarterly Free Cash Flow of -$8.7 million for Q1 2026, up 31.31% year-over-year from -$6.7 million in Q1 2025, and down 236.59% quarter-over-quarter from $6.4 million in Q4 2025.

Spruce Biosciences (SPRB) Free Cash Flow (2019 - 2026) Analysis & Trends

Spruce Biosciences (SPRB) has reported Free Cash Flow for 8 consecutive years, with -$8.7 million the latest figure, recorded in Q1 2026.

  • In Q1 2026, Free Cash Flow rose 31.31% year-over-year to -$8.7 million; the TTM figure through Mar 2026 stood at $37.3 million (up 169.39% YoY), while the FY2025 annual figure was $33.3 million, up 159.5% from the prior year.
  • Free Cash Flow eased to -$8.7 million in Q1 2026 per SPRB's latest filing, from $6.4 million in the prior quarter.
  • Across five years, Free Cash Flow topped out at $48.5 million in Q3 2025 and bottomed at -$20.7 million in Q4 2024.
  • Historically, Free Cash Flow has averaged -$6.3 million across 5 years, with a median of -$11.1 million in 2024.
  • Annual changes were most pronounced in 2024 — Free Cash Flow plunged 657.25% — and 2025, when it surged 625.37%.
  • Spruce Biosciences' Free Cash Flow stood at -$11.7 million in 2022, then grew by 4.51% to -$11.2 million in 2023, then slumped by 84.47% to -$20.7 million in 2024, then surged by 130.95% to $6.4 million in 2025, then tumbled by 236.59% to -$8.7 million in 2026.
  • Business Quant data shows SPRB's Free Cash Flow at -$8.7 million in Q1 2026, $6.4 million in Q4 2025, and $48.5 million in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Free Cash Flow (Qtr)
1 Vertex Pharmaceuticals 139.13 Bn 131.28 Bn 2.84 Bn 1.01 Bn
2 Regeneron Pharmaceuticals 85.77 Bn 77.77 Bn 3.93 Bn 572.80 Mn
3 Argenx Se 64.64 Bn 59.46 Bn 1.37 Bn -
4 Moderna 58.29 Bn 53.16 Bn 52.00 Mn -563.00 Mn
5 BeOne Medicines 41.92 Bn 36.82 Bn 1.53 Bn 437.80 Mn
6 Alnylam Pharmaceuticals 31.58 Bn 28.28 Bn 992.69 Mn 292.04 Mn
7 BioNTech SE 28.12 Bn 9.73 Bn 668.28 Mn 433.84 Mn
8 Insmed 27.39 Bn 26.22 Bn 358.27 Mn -95.09 Mn
9 Royalty Pharma 27.27 Bn 26.43 Bn - 477.44 Mn
10 Spruce Biosciences 119.20 Mn 119.20 Mn - 39.50 Mn

Historic Data

Download Data
DateValue
Jun 30, 2026 39.50 Mn
Jun 30, 2026 39.50 Mn
Mar 31, 2026 -8.74 Mn
Mar 31, 2026 -8.74 Mn
Dec 31, 2025 6.40 Mn
Dec 31, 2025 6.40 Mn
Sep 30, 2025 48.46 Mn
Sep 30, 2025 48.46 Mn
Jun 30, 2025 -8.83 Mn
Jun 30, 2025 -8.83 Mn
Mar 31, 2025 -12.73 Mn
Mar 31, 2025 -12.73 Mn
Dec 31, 2024 -20.68 Mn
Dec 31, 2024 -20.68 Mn
Sep 30, 2024 -9.22 Mn
Sep 30, 2024 -9.22 Mn
Jun 30, 2024 -11.11 Mn
Jun 30, 2024 -11.11 Mn
Mar 31, 2024 -14.96 Mn
Mar 31, 2024 -14.96 Mn