Spruce Biosciences SPRB
NASDAQ SPRB
$49.03 -2.96 (-5.68%)
As of: Aug 21, 2026 · 3:48 PM EDT

Spruce Biosciences (SPRB) Cash from Operations (2019 - 2026)

Spruce Biosciences (SPRB) posted quarterly Cash from Operations of 8732000.0 for Q1 2026, up 31.39% year-over-year from 6645865.57 in Q1 2025, and down 236.44% quarter-over-quarter from 6400000.0 in Q4 2025.

Spruce Biosciences (SPRB) Cash from Operations (2019 - 2026) Analysis & Trends

Spruce Biosciences (SPRB) has reported Cash from Operations for 8 consecutive years, with 8732000.0 the latest figure, recorded in Q1 2026.

  • In Q1 2026, Cash from Operations rose 31.39% year-over-year to 8732000.0; the TTM figure through Mar 2026 stood at 37295000.0 (up 169.41% YoY), while the FY2025 annual figure was 33300000.0, up 159.5% from the prior year.
  • Cash from Operations eased to 8732000.0 in Q1 2026 per SPRB's latest filing, from 6400000.0 in the prior quarter.
  • Across five years, Cash from Operations topped out at 48455000.0 in Q3 2025 and bottomed at 20677000.0 in Q4 2024.
  • Historically, Cash from Operations has averaged 6256117.65 across 5 years, with a median of 11106000.0 in 2024.
  • Annual changes were most pronounced in 2024 — Cash from Operations plunged 657.25% — and 2025, when it surged 625.37%.
  • Spruce Biosciences' Cash from Operations stood at 11738000.0 in 2022, then grew by 4.51% to 11209000.0 in 2023, then slumped by 84.47% to 20677000.0 in 2024, then surged by 130.95% to 6400000.0 in 2025, then tumbled by 236.44% to 8732000.0 in 2026.
  • Business Quant data shows SPRB's Cash from Operations at 8732000.0 in Q1 2026, 6400000.0 in Q4 2025, and 48455000.0 in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Cash from Ops. (Qtr)
1 Vertex Pharmaceuticals 139.03 Bn 131.18 Bn 2.84 Bn 1.13 Bn
2 Regeneron Pharmaceuticals 85.64 Bn 77.64 Bn 3.93 Bn 813.00 Mn
3 Argenx Se 64.93 Bn 59.75 Bn 1.37 Bn -
4 Moderna 57.93 Bn 52.80 Bn 52.00 Mn -526.00 Mn
5 BeOne Medicines 41.95 Bn 36.86 Bn 1.53 Bn 462.82 Mn
6 Alnylam Pharmaceuticals 31.51 Bn 28.20 Bn 992.69 Mn 326.72 Mn
7 BioNTech SE 28.00 Bn 9.60 Bn 668.28 Mn 360.27 Mn
8 Insmed 27.42 Bn 26.26 Bn 358.27 Mn -88.83 Mn
9 Royalty Pharma 27.29 Bn 26.45 Bn - 728.46 Mn
10 Spruce Biosciences 119.20 Mn 119.20 Mn - 39.63 Mn

Historic Data

Download Data
DateValue
Jun 30, 2026 39.63 Mn
Jun 30, 2026 39.63 Mn
Mar 31, 2026 -8.73 Mn
Mar 31, 2026 -8.73 Mn
Dec 31, 2025 6.40 Mn
Dec 31, 2025 6.40 Mn
Sep 30, 2025 48.46 Mn
Sep 30, 2025 48.46 Mn
Jun 30, 2025 -8.83 Mn
Jun 30, 2025 -8.83 Mn
Mar 31, 2025 -12.73 Mn
Mar 31, 2025 -12.73 Mn
Dec 31, 2024 -20.68 Mn
Dec 31, 2024 -20.68 Mn
Sep 30, 2024 -9.22 Mn
Sep 30, 2024 -9.22 Mn
Jun 30, 2024 -11.11 Mn
Jun 30, 2024 -11.11 Mn
Mar 31, 2024 -14.96 Mn
Mar 31, 2024 -14.96 Mn