SOPHiA GENETICS (SOPH) Return on Sales [ROS] (2020 - 2026)
SOPHiA GENETICS (SOPH) posted Return on Sales [ROS] of -86.03% for the quarter ended Jun 30, 2026, up 14.89 percentage points from -100.92% a year earlier but down 6.34 percentage points from the prior quarter.
SOPHiA GENETICS (SOPH) Return on Sales [ROS] (2020 - 2026) Analysis & Trends
For the trailing twelve months through Jun 30, 2026, Return on Sales [ROS] at SOPHiA GENETICS was -85.55%, up 11.08 percentage points year-over-year; for the year ended Dec 31, 2025, it came in at -91.76%, up 10.38 percentage points from the prior year.
- Annual Return on Sales [ROS] has increased for three consecutive years, with a five-year change of +39.88 percentage points (years ended Dec 2020 to Dec 2025).
- In prior years, SOPHiA GENETICS's Return on Sales [ROS] was -102.14% in the year ended Dec 31, 2024 (+17.83 pp), -119.97% in the year ended Dec 31, 2023 (+64.69 pp), -184.66% in the year ended Dec 31, 2022 (-7.92 pp) and -176.73% in the year ended Dec 31, 2021 (-45.09 pp).
- Quarterly Return on Sales [ROS] has run from a low of -230.37% in the quarter ended Mar 31, 2022 to a high of -79.69% in the quarter ended Mar 31, 2026 over five years.
- On a year-over-year basis, Return on Sales [ROS] has increased in each of the last four quarters, with an average year-over-year change of +10.45 percentage points over the last eight quarters.
- The strongest year-over-year quarter for Return on Sales [ROS] in the past five years was the quarter ended Sep 30, 2023, with a gain of 101.47 percentage points; the weakest was the quarter ended Mar 31, 2022, with a drop of 73.80 percentage points.
- According to Business Quant data, Return on Sales [ROS] for the three prior quarters was -79.69% (quarter ended Mar 31, 2026), -85.30% (quarter ended Dec 31, 2025) and -91.78% (quarter ended Sep 30, 2025).
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | ROS (Qtr) |
|---|---|---|---|---|---|
| 1 | Bryn | 945.00 Bn | 945.00 Bn | - | - |
| 2 | Veeva Systems | 44.24 Bn | 16.49 Bn | 695.95 Mn | 29.64% |
| 3 | Samsara | 24.06 Bn | 20.83 Bn | 392.58 Mn | 0.96% |
| 4 | Toast | 17.18 Bn | 9.85 Bn | 516.00 Mn | 7.97% |
| 5 | Ptc | 15.95 Bn | 14.76 Bn | 490.47 Mn | 27.75% |
| 6 | Duolingo | 13.49 Bn | 8.67 Bn | 216.74 Mn | 11.37% |
| 7 | Trimble | 13.41 Bn | 12.48 Bn | 674.90 Mn | 13.58% |
| 8 | Manhattan Associates | 11.90 Bn | 10.90 Bn | 168.33 Mn | 22.24% |
| 9 | Costar | 11.09 Bn | 5.06 Bn | 728.00 Mn | 8.22% |
| 10 | SOPHiA GENETICS | 552.68 Mn | 227.73 Mn | 15.06 Mn | -86.03% |
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | -86.03% |
| Mar 31, 2026 | -79.69% |
| Dec 31, 2025 | -85.30% |
| Sep 30, 2025 | -91.78% |
| Jun 30, 2025 | -100.92% |
| Mar 31, 2025 | -90.20% |
| Dec 31, 2024 | -98.37% |
| Sep 30, 2024 | -96.91% |
| Jun 30, 2024 | -94.92% |
| Mar 31, 2024 | -118.87% |
| Dec 31, 2023 | -111.13% |
| Sep 30, 2023 | -101.48% |
| Jun 30, 2023 | -133.17% |
| Mar 31, 2023 | -138.10% |
| Dec 31, 2022 | -112.69% |
| Sep 30, 2022 | -202.94% |
| Jun 30, 2022 | -206.39% |
| Mar 31, 2022 | -230.37% |
| Dec 31, 2021 | -192.09% |
| Sep 30, 2021 | -197.91% |
SOPHiA GENETICS Return on Sales [ROS] API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=return-on-sales-%5Bros%5D&ticker=SOPH&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "return-on-sales-[ros]", "ticker": "SOPH", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=return-on-sales-%5Bros%5D&ticker=SOPH&period=max&api_key=YOUR_API_KEY");
const data = await res.json();