SOPHiA GENETICS (SOPH) Return on Equity [ROE] (2021 - 2026)
SOPHiA GENETICS (SOPH) recorded Return on Equity [ROE] of -125.58% in the quarter ended Jun 30, 2026, down 35.14 percentage points from -90.44% a year earlier but up 48.79 percentage points from the prior quarter.
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Analysis
SOPHiA GENETICS (SOPH) Return on Equity [ROE] (2021 - 2026) Analysis & Trends
For the year ended Dec 31, 2025, SOPHiA GENETICS reported Return on Equity [ROE] of -110.00%, down 59.59 percentage points from the prior year.
- Annual Return on Equity [ROE] has declined for three straight years, though with a five-year change of +7.92 percentage points (years ended Dec 2020 to Dec 2025).
- Across earlier years, Return on Equity [ROE] came in at -50.41% in the year ended Dec 31, 2024 (-5.48 pp), -44.93% in the year ended Dec 31, 2023 (-8.15 pp), -36.78% in the year ended Dec 31, 2022 (+2.42 pp) and -39.20% in the year ended Dec 31, 2021 (+78.73 pp).
- Quarterly Return on Equity [ROE] has ranged from -274.11% in the quarter ended Mar 31, 2024 to -34.80% in the quarter ended Sep 30, 2021 over the past five years.
- On a year-over-year basis, Return on Equity [ROE] has declined for five consecutive quarters, with an average year-over-year change of +1.46 percentage points over the last eight quarters.
- Peak year-over-year performance for Return on Equity [ROE] in the last five years was a gain of 201.44 percentage points in the quarter ended Mar 31, 2025, against a drop of 106.54 percentage points in the quarter ended Mar 31, 2024 at the low end.
- Per Business Quant, the preceding three quarters came in at -174.37% (quarter ended Mar 31, 2026), -146.52% (quarter ended Dec 31, 2025) and -109.15% (quarter ended Sep 30, 2025).
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | ROE (Qtr) |
|---|---|---|---|---|---|
| 1 | Bryn | 945.00 Bn | 945.00 Bn | - | - |
| 2 | Veeva Systems | 46.20 Bn | 18.45 Bn | 695.95 Mn | 13.77% |
| 3 | Samsara | 22.32 Bn | 19.09 Bn | 392.58 Mn | 5.82% |
| 4 | Toast | 16.73 Bn | 9.40 Bn | 516.00 Mn | 24.09% |
| 5 | Ptc | 15.53 Bn | 14.35 Bn | 490.47 Mn | 33.39% |
| 6 | Duolingo | 13.32 Bn | 8.49 Bn | 216.74 Mn | 29.32% |
| 7 | Trimble | 13.32 Bn | 12.38 Bn | 674.90 Mn | -1.95% |
| 8 | Manhattan Associates | 11.58 Bn | 10.58 Bn | 168.33 Mn | 115.93% |
| 9 | Costar | 11.10 Bn | 5.07 Bn | 728.00 Mn | 0.93% |
| 10 | SOPHiA GENETICS | 573.92 Mn | 248.96 Mn | 15.06 Mn | -125.58% |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | -125.58% |
| Mar 31, 2026 | -174.37% |
| Dec 31, 2025 | -146.52% |
| Sep 30, 2025 | -109.15% |
| Jun 30, 2025 | -90.44% |
| Mar 31, 2025 | -72.68% |
| Dec 31, 2024 | -59.52% |
| Sep 30, 2024 | -60.77% |
| Jun 30, 2024 | -52.65% |
| Mar 31, 2024 | -274.11% |
| Dec 31, 2023 | -198.80% |
| Sep 30, 2023 | -41.73% |
| Jun 30, 2023 | -43.96% |
| Mar 31, 2023 | -167.58% |
| Dec 31, 2022 | -147.67% |
| Sep 30, 2022 | -43.71% |
| Jun 30, 2022 | -38.66% |
| Mar 31, 2022 | -97.06% |
| Dec 31, 2021 | -68.21% |
| Sep 30, 2021 | -34.80% |
API Access
SOPHiA GENETICS Return on Equity [ROE] API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=return-on-equity-%5Broe%5D&ticker=SOPH&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "return-on-equity-[roe]", "ticker": "SOPH", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=return-on-equity-%5Broe%5D&ticker=SOPH&period=max&api_key=YOUR_API_KEY");
const data = await res.json();