SOPHiA GENETICS (SOPH) Operating Income (2020 - 2025)
SOPHiA GENETICS's (SOPH) quarterly Operating Income came in at -$18.5 million in Q4 2025, down 6.15% year-on-year from -$19.7 million in Q4 2024, and down 3.66% quarter-over-quarter from -$17.9 million in Q3 2025.
SOPHiA GENETICS (SOPH) Operating Income (2020 - 2025) Analysis & Trends
SOPHiA GENETICS has disclosed Operating Income across 6 years of filings, most recently posting -$18.5 million for Q4 2025.
- Operating Income for Q4 2025 came in at -$18.5 million, down 6.15% year-over-year; the trailing twelve-month figure through Dec 2025 was -$70.9 million (down 6.52% YoY), and the FY2025 annual result was -$70.9 million, down 6.52% from the prior year.
- Operating Income came in at -$18.5 million for Q4 2025 at SOPHiA GENETICS, down from -$17.9 million in the prior quarter.
- In the past five years, Operating Income ranged from a high of -$14.1 million in Q1 2021 to a low of -$20502.0 billion in Q3 2021.
- The 5-year median for Operating Income is -$18.5 million (2025), against an average of -$1025.1 billion.
- Across the five-year window, Operating Income sank 217389460190.53% in 2021 and jumped 100.0% in 2022, its largest moves.
- SOPHiA GENETICS's Operating Income stood at -$21.0 million in 2021, then rose by 28.21% to -$15.1 million in 2022, then retreated by 25.61% to -$18.9 million in 2023, then advanced by 7.93% to -$17.4 million in 2024, then decreased by 6.15% to -$18.5 million in 2025.
- The last three Operating Income figures came in at -$18.5 million (Q4 2025), -$17.9 million (Q3 2025), and -$18.5 million (Q2 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Op. Inc (Qtr) |
|---|---|---|---|---|---|
| 1 | Veeva Systems | 24.83 Bn | 17.52 Bn | 662.02 Mn | 273.11 Mn |
| 2 | BrightSpring Health Services | 13.57 Bn | 12.69 Bn | 482.22 Mn | 121.45 Mn |
| 3 | Healthequity | 7.20 Bn | 6.93 Bn | 256.31 Mn | 102.95 Mn |
| 4 | Hinge Health | 5.42 Bn | 5.11 Bn | 154.23 Mn | 32.07 Mn |
| 5 | 10x Genomics | 4.46 Bn | 3.92 Bn | 106.18 Mn | -17.05 Mn |
| 6 | Doximity | 3.81 Bn | 3.06 Bn | 125.97 Mn | 24.83 Mn |
| 7 | Waystar Holding | 3.52 Bn | 3.36 Bn | 268.04 Mn | 80.47 Mn |
| 8 | Privia Health | 2.94 Bn | 2.57 Bn | 595.71 Mn | 7.42 Mn |
| 9 | Omnicell | 1.76 Bn | 1.59 Bn | 140.36 Mn | 16.85 Mn |
| 10 | SOPHiA GENETICS | 26.19 Mn | -44.10 Mn | 14.69 Mn | -18.52 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Dec 31, 2025 | -18.52 Mn |
| Sep 30, 2025 | -17.86 Mn |
| Jun 30, 2025 | -18.49 Mn |
| Mar 31, 2025 | -16.04 Mn |
| Dec 31, 2024 | -17.44 Mn |
| Sep 30, 2024 | -15.36 Mn |
| Jun 30, 2024 | -15.01 Mn |
| Mar 31, 2024 | -18.76 Mn |
| Dec 31, 2023 | -18.95 Mn |
| Sep 30, 2023 | -16.54 Mn |
| Jun 30, 2023 | -20.05 Mn |
| Mar 31, 2023 | -19.29 Mn |
| Dec 31, 2022 | -15.08 Mn |
| Sep 30, 2022 | -23.64 Mn |
| Jun 30, 2022 | -24.08 Mn |
| Mar 31, 2022 | -25.02 Mn |
| Dec 31, 2021 | -21.01 Mn |
| Sep 30, 2021 | -20,502.00 Bn |
| Jun 30, 2021 | -15.92 Mn |
| Mar 31, 2021 | -14.05 Mn |