SOPHiA GENETICS (SOPH) Operating Income (2020 - 2025)

SOPHiA GENETICS's (SOPH) quarterly Operating Income came in at -$18.5 million in Q4 2025, down 6.15% year-on-year from -$19.7 million in Q4 2024, and down 3.66% quarter-over-quarter from -$17.9 million in Q3 2025.

SOPHiA GENETICS (SOPH) Operating Income (2020 - 2025) Analysis & Trends

SOPHiA GENETICS has disclosed Operating Income across 6 years of filings, most recently posting -$18.5 million for Q4 2025.

  • Operating Income for Q4 2025 came in at -$18.5 million, down 6.15% year-over-year; the trailing twelve-month figure through Dec 2025 was -$70.9 million (down 6.52% YoY), and the FY2025 annual result was -$70.9 million, down 6.52% from the prior year.
  • Operating Income came in at -$18.5 million for Q4 2025 at SOPHiA GENETICS, down from -$17.9 million in the prior quarter.
  • In the past five years, Operating Income ranged from a high of -$14.1 million in Q1 2021 to a low of -$20502.0 billion in Q3 2021.
  • The 5-year median for Operating Income is -$18.5 million (2025), against an average of -$1025.1 billion.
  • Across the five-year window, Operating Income sank 217389460190.53% in 2021 and jumped 100.0% in 2022, its largest moves.
  • SOPHiA GENETICS's Operating Income stood at -$21.0 million in 2021, then rose by 28.21% to -$15.1 million in 2022, then retreated by 25.61% to -$18.9 million in 2023, then advanced by 7.93% to -$17.4 million in 2024, then decreased by 6.15% to -$18.5 million in 2025.
  • The last three Operating Income figures came in at -$18.5 million (Q4 2025), -$17.9 million (Q3 2025), and -$18.5 million (Q2 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Op. Inc (Qtr)
1 Veeva Systems 24.83 Bn 17.52 Bn 662.02 Mn 273.11 Mn
2 BrightSpring Health Services 13.57 Bn 12.69 Bn 482.22 Mn 121.45 Mn
3 Healthequity 7.20 Bn 6.93 Bn 256.31 Mn 102.95 Mn
4 Hinge Health 5.42 Bn 5.11 Bn 154.23 Mn 32.07 Mn
5 10x Genomics 4.46 Bn 3.92 Bn 106.18 Mn -17.05 Mn
6 Doximity 3.81 Bn 3.06 Bn 125.97 Mn 24.83 Mn
7 Waystar Holding 3.52 Bn 3.36 Bn 268.04 Mn 80.47 Mn
8 Privia Health 2.94 Bn 2.57 Bn 595.71 Mn 7.42 Mn
9 Omnicell 1.76 Bn 1.59 Bn 140.36 Mn 16.85 Mn
10 SOPHiA GENETICS 26.19 Mn -44.10 Mn 14.69 Mn -18.52 Mn

Historic Data

Download Data
DateValue
Dec 31, 2025 -18.52 Mn
Sep 30, 2025 -17.86 Mn
Jun 30, 2025 -18.49 Mn
Mar 31, 2025 -16.04 Mn
Dec 31, 2024 -17.44 Mn
Sep 30, 2024 -15.36 Mn
Jun 30, 2024 -15.01 Mn
Mar 31, 2024 -18.76 Mn
Dec 31, 2023 -18.95 Mn
Sep 30, 2023 -16.54 Mn
Jun 30, 2023 -20.05 Mn
Mar 31, 2023 -19.29 Mn
Dec 31, 2022 -15.08 Mn
Sep 30, 2022 -23.64 Mn
Jun 30, 2022 -24.08 Mn
Mar 31, 2022 -25.02 Mn
Dec 31, 2021 -21.01 Mn
Sep 30, 2021 -20,502.00 Bn
Jun 30, 2021 -15.92 Mn
Mar 31, 2021 -14.05 Mn