SOPHiA GENETICS (SOPH) Operating Income (2020 - 2025)

SOPHiA GENETICS (SOPH) reported Operating Income of -$18.5 million for Q4 2025, down 6.15% on a YoY basis from -$19.7 million in Q4 2024, and down 3.66% sequentially from -$17.9 million in Q3 2025.

SOPHiA GENETICS (SOPH) Operating Income (2020 - 2025) Analysis & Trends

SOPHiA GENETICS (SOPH) has 6 years of Operating Income data on file, last reported at -$18.5 million in Q4 2025.

  • For the quarter ending Q4 2025, Operating Income fell 6.15% year-over-year to -$18.5 million; the trailing twelve-month figure through Dec 2025 stood at -$70.9 million (down 6.52% YoY), and the FY2025 full-year result was -$70.9 million, down 6.52% from the prior year.
  • Operating Income declined to -$18.5 million in Q4 2025, from -$17.9 million in the prior quarter.
  • In the past five years, Operating Income ranged from a high of -$14.1 million in Q1 2021 to a low of -$25.0 million in Q1 2022.
  • A 5-year average of -$18.6 million and a median of -$18.5 million in 2025 frame the typical range for Operating Income.
  • Peak annual rise in Operating Income reached 99.77% in 2021, while the deepest fall reached 217289.46% in 2021.
  • Tracing SOPH's Operating Income over 5 years: stood at -$21.0 million in 2021, then increased by 28.21% to -$15.1 million in 2022, then fell by 25.61% to -$18.9 million in 2023, then gained by 7.93% to -$17.4 million in 2024, then retreated by 6.15% to -$18.5 million in 2025.
  • Business Quant data shows SOPH's Operating Income at -$18.5 million in Q4 2025, -$17.9 million in Q3 2025, and -$18.5 million in Q2 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Op. Inc (Qtr)
1 Veeva Systems 29.34 Bn 22.03 Bn 662.02 Mn 273.11 Mn
2 BrightSpring Health Services 13.49 Bn 12.59 Bn 482.22 Mn 121.45 Mn
3 Healthequity 7.96 Bn 7.70 Bn 256.31 Mn 102.95 Mn
4 10x Genomics 6.17 Bn 5.63 Bn 106.18 Mn -17.05 Mn
5 Hinge Health 6.02 Bn 5.70 Bn 154.23 Mn 32.07 Mn
6 MiniMed 4.19 Bn 3.89 Bn 480.00 Mn -93.00 Mn
7 Waystar Holding 4.14 Bn 4.07 Bn 216.84 Mn 80.47 Mn
8 Doximity 3.82 Bn 3.08 Bn 125.97 Mn 24.83 Mn
9 Privia Health 3.10 Bn 2.73 Bn - 7.42 Mn
10 SOPHiA GENETICS 408.62 Mn 338.33 Mn 14.69 Mn -18.52 Mn

Historic Data

Download Data
DateValue
Dec 31, 2025 -18.52 Mn
Sep 30, 2025 -17.86 Mn
Jun 30, 2025 -18.49 Mn
Mar 31, 2025 -16.04 Mn
Dec 31, 2024 -17.44 Mn
Sep 30, 2024 -15.36 Mn
Jun 30, 2024 -15.01 Mn
Mar 31, 2024 -18.76 Mn
Dec 31, 2023 -18.95 Mn
Sep 30, 2023 -16.54 Mn
Jun 30, 2023 -20.05 Mn
Mar 31, 2023 -19.29 Mn
Dec 31, 2022 -15.08 Mn
Sep 30, 2022 -23.64 Mn
Jun 30, 2022 -24.08 Mn
Mar 31, 2022 -25.02 Mn
Dec 31, 2021 -21.01 Mn
Sep 30, 2021 -20.50 Mn
Jun 30, 2021 -15.92 Mn
Mar 31, 2021 -14.05 Mn