SOPHiA GENETICS (SOPH) Net Margin (2020 - 2026)
SOPHiA GENETICS's Net Margin was -83.54% in Q3 2026, up 19.33 percentage points from -102.87% a year earlier and up 12.37 percentage points from the prior quarter.
Powered by 
Analysis
SOPHiA GENETICS (SOPH) Net Margin (2020 - 2026) Analysis & Trends
On a trailing twelve-month basis, SOPHiA GENETICS's Net Margin was -89.18% through Sep 30, 2026, up 13.11 percentage points year-over-year; for FY2025, it was -102.24%, down 6.35 percentage points from FY2024.
- Net Margin shows a five-year change of +36.28 percentage points (FY2020 to FY2025).
- In earlier years, Net Margin was -95.89% in FY2024 (+30.74 pp), -126.63% in FY2023 (+57.24 pp), -183.87% in FY2022 (-1.73 pp) and -182.14% in FY2021 (-43.62 pp).
- The Q3 2026 figure marks the highest quarterly Net Margin in data going back to Q2 2020.
- Compared with a year earlier, Net Margin has increased for three straight quarters, with an average year-over-year change of +10.44 percentage points over the last eight quarters.
- The best year-over-year quarter for Net Margin over five years was Q3 2023 (a gain of 115.33 percentage points); the worst was Q1 2022 (a drop of 93.53 percentage points).
- Per Business Quant data, SOPH's Net Margin in the three quarters before Q3 2026 was -95.91% (Q2 2026), -89.09% (Q1 2026) and -88.35% (Q4 2025).
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Net Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Bryn | 945.00 Bn | 945.00 Bn | - | - |
| 2 | Veeva Systems | 49.39 Bn | 21.63 Bn | 695.95 Mn | 29.47% |
| 3 | Samsara | 23.96 Bn | 20.73 Bn | 392.58 Mn | 3.19% |
| 4 | Ptc | 22.37 Bn | 21.18 Bn | 490.47 Mn | 19.80% |
| 5 | Toast | 20.05 Bn | 12.69 Bn | 543.00 Mn | 8.53% |
| 6 | Manhattan Associates | 14.85 Bn | 13.91 Bn | 174.30 Mn | 20.03% |
| 7 | Bentley Systems | 13.89 Bn | 13.37 Bn | 349.55 Mn | 21.34% |
| 8 | Trimble | 12.57 Bn | 11.65 Bn | 659.10 Mn | 6.11% |
| 9 | Costar | 12.28 Bn | 7.66 Bn | 741.00 Mn | 7.77% |
| 10 | SOPHiA GENETICS | 482.23 Mn | 143.24 Mn | 15.93 Mn | -83.54% |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Sep 30, 2026 | -83.54% |
| Jun 30, 2026 | -95.91% |
| Mar 31, 2026 | -89.09% |
| Dec 31, 2025 | -88.35% |
| Sep 30, 2025 | -102.87% |
| Jun 30, 2025 | -122.33% |
| Mar 31, 2025 | -97.78% |
| Dec 31, 2024 | -85.48% |
| Sep 30, 2024 | -116.31% |
| Jun 30, 2024 | -96.11% |
| Mar 31, 2024 | -86.85% |
| Dec 31, 2023 | -141.13% |
| Sep 30, 2023 | -84.79% |
| Jun 30, 2023 | -142.13% |
| Mar 31, 2023 | -141.06% |
| Dec 31, 2022 | -104.39% |
| Sep 30, 2022 | -200.12% |
| Jun 30, 2022 | -211.55% |
| Mar 31, 2022 | -234.67% |
| Dec 31, 2021 | -195.43% |
API Access
SOPHiA GENETICS Net Margin API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=net-margin&ticker=SOPH&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "net-margin", "ticker": "SOPH", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=net-margin&ticker=SOPH&period=max&api_key=YOUR_API_KEY");
const data = await res.json();