SOPHiA GENETICS (SOPH) Net Margin (2020 - 2026)
SOPHiA GENETICS's Net Margin was -95.91% in the quarter ended Jun 30, 2026, up 26.42 percentage points from -122.33% a year earlier but down 6.82 percentage points from the prior quarter.
SOPHiA GENETICS (SOPH) Net Margin (2020 - 2026) Analysis & Trends
On a trailing twelve-month basis, SOPHiA GENETICS's Net Margin was -93.86% through Jun 30, 2026, up 11.46 percentage points year-over-year; for the year ended Dec 31, 2025, it was -102.24%, down 6.35 percentage points from the prior year.
- Net Margin shows a five-year change of +36.28 percentage points (years ended Dec 2020 to Dec 2025).
- In earlier years, Net Margin was -95.89% in the year ended Dec 31, 2024 (+30.74 pp), -126.63% in the year ended Dec 31, 2023 (+57.24 pp), -183.87% in the year ended Dec 31, 2022 (-1.73 pp) and -182.14% in the year ended Dec 31, 2021 (-43.62 pp).
- Quarterly Net Margin has moved between -234.67% (the quarter ended Mar 31, 2022) and -84.79% (the quarter ended Sep 30, 2023) over five years.
- Compared with a year earlier, Net Margin was higher in four of the last eight quarters, with an average year-over-year change of +4.08 percentage points.
- The best year-over-year quarter for Net Margin over five years was the quarter ended Sep 30, 2023 (a gain of 115.33 percentage points); the worst was the quarter ended Mar 31, 2022 (a drop of 93.53 percentage points).
- Per Business Quant data, SOPH's Net Margin in the three quarters before the quarter ended Jun 30, 2026 was -89.09% (quarter ended Mar 31, 2026), -88.35% (quarter ended Dec 31, 2025) and -102.87% (quarter ended Sep 30, 2025).
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Net Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Bryn | 945.00 Bn | 945.00 Bn | - | - |
| 2 | Veeva Systems | 45.35 Bn | 17.59 Bn | 695.95 Mn | 29.47% |
| 3 | Samsara | 22.20 Bn | 18.97 Bn | 392.58 Mn | 3.19% |
| 4 | Toast | 17.53 Bn | 10.20 Bn | 516.00 Mn | 8.07% |
| 5 | Ptc | 15.47 Bn | 14.28 Bn | 490.47 Mn | 19.80% |
| 6 | Trimble | 13.41 Bn | 12.48 Bn | 674.90 Mn | -48.53% |
| 7 | Duolingo | 12.56 Bn | 7.73 Bn | 216.74 Mn | 11.11% |
| 8 | Manhattan Associates | 11.77 Bn | 10.77 Bn | 168.33 Mn | 16.91% |
| 9 | Costar | 10.95 Bn | 4.91 Bn | 728.00 Mn | 5.95% |
| 10 | SOPHiA GENETICS | 581.45 Mn | 256.49 Mn | 15.06 Mn | -95.91% |
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | -95.91% |
| Mar 31, 2026 | -89.09% |
| Dec 31, 2025 | -88.35% |
| Sep 30, 2025 | -102.87% |
| Jun 30, 2025 | -122.33% |
| Mar 31, 2025 | -97.78% |
| Dec 31, 2024 | -85.48% |
| Sep 30, 2024 | -116.31% |
| Jun 30, 2024 | -96.11% |
| Mar 31, 2024 | -86.85% |
| Dec 31, 2023 | -141.13% |
| Sep 30, 2023 | -84.79% |
| Jun 30, 2023 | -142.13% |
| Mar 31, 2023 | -141.06% |
| Dec 31, 2022 | -104.39% |
| Sep 30, 2022 | -200.12% |
| Jun 30, 2022 | -211.55% |
| Mar 31, 2022 | -234.67% |
| Dec 31, 2021 | -195.43% |
| Sep 30, 2021 | -205.07% |
SOPHiA GENETICS Net Margin API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=net-margin&ticker=SOPH&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "net-margin", "ticker": "SOPH", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=net-margin&ticker=SOPH&period=max&api_key=YOUR_API_KEY");
const data = await res.json();