SOPHiA GENETICS (SOPH) Net Income (2020 - 2025)

SOPHiA GENETICS's (SOPH) quarterly Net Income came in at -$20.0 million in Q4 2025, down 43.39% year-on-year from -$35.3 million in Q4 2024, and down 6.58% quarter-over-quarter from -$18.7 million in Q3 2025.

SOPHiA GENETICS (SOPH) Net Income (2020 - 2025) Analysis & Trends

SOPHiA GENETICS has disclosed Net Income across 6 years of filings, most recently posting -$20.0 million for Q4 2025.

  • Net Income for Q4 2025 came in at -$20.0 million, down 43.39% year-over-year; the trailing twelve-month figure through Dec 2025 was -$76.0 million (down 26.53% YoY), and the FY2025 annual result was -$76.0 million, down 26.53% from the prior year.
  • Net Income came in at -$20.0 million for Q4 2025 at SOPHiA GENETICS, down from -$18.7 million in the prior quarter.
  • In the past five years, Net Income ranged from a high of -$12.3 million in Q1 2021 to a low of -$25.0 million in Q1 2022.
  • The 5-year median for Net Income is -$19.1 million (2023), against an average of -$18.8 million.
  • Across the five-year window, Net Income jumped 99.81% in 2021 and slumped 103.13% in 2022, its largest moves.
  • SOPHiA GENETICS's Net Income stood at -$22.4 million in 2021, then jumped by 35.4% to -$14.5 million in 2022, then plunged by 66.1% to -$24.1 million in 2023, then jumped by 42.12% to -$13.9 million in 2024, then plunged by 43.39% to -$20.0 million in 2025.
  • The last three Net Income figures came in at -$20.0 million (Q4 2025), -$18.7 million (Q3 2025), and -$20.9 million (Q2 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Net Income (Qtr)
1 Veeva Systems 24.83 Bn 17.52 Bn 662.02 Mn 260.94 Mn
2 BrightSpring Health Services 13.57 Bn 12.69 Bn 482.22 Mn 74.33 Mn
3 Healthequity 7.20 Bn 6.93 Bn 256.31 Mn 69.42 Mn
4 Hinge Health 5.42 Bn 5.11 Bn 154.23 Mn 35.13 Mn
5 10x Genomics 4.46 Bn 3.92 Bn 106.18 Mn -13.47 Mn
6 Doximity 3.81 Bn 3.06 Bn 125.97 Mn 19.11 Mn
7 Waystar Holding 3.52 Bn 3.36 Bn 268.04 Mn 43.32 Mn
8 Privia Health 2.94 Bn 2.57 Bn 595.71 Mn 3.71 Mn
9 Omnicell 1.76 Bn 1.59 Bn 140.36 Mn 11.41 Mn
10 SOPHiA GENETICS 26.19 Mn -44.10 Mn 14.69 Mn -19.97 Mn

Historic Data

Download Data
DateValue
Dec 31, 2025 -19.97 Mn
Sep 30, 2025 -18.74 Mn
Jun 30, 2025 -20.89 Mn
Mar 31, 2025 -16.38 Mn
Dec 31, 2024 -13.93 Mn
Sep 30, 2024 -18.18 Mn
Jun 30, 2024 -14.87 Mn
Mar 31, 2024 -13.07 Mn
Dec 31, 2023 -24.06 Mn
Sep 30, 2023 -13.23 Mn
Jun 30, 2023 -21.25 Mn
Mar 31, 2023 -19.49 Mn
Dec 31, 2022 -14.49 Mn
Sep 30, 2022 -23.52 Mn
Jun 30, 2022 -24.69 Mn
Mar 31, 2022 -25.02 Mn
Dec 31, 2021 -22.42 Mn
Sep 30, 2021 -20.29 Mn
Jun 30, 2021 -18.31 Mn
Mar 31, 2021 -12.32 Mn