Growth Metrics

SOPHiA GENETICS (SOPH) EBITDA (2020 - 2025)

SOPHiA GENETICS recorded quarterly EBITDA of -$18.5 million in Q4 2025, down 3.66% quarter-over-quarter from -$17.9 million in Q3 2025, and down 104.57% year-over-year from $404.8 million in Q4 2024.

SOPHiA GENETICS's EBITDA history runs 6 years deep, the most recent figure standing at -$18.5 million for Q4 2025.

  • In Q4 2025, EBITDA fell 104.57% year-over-year to -$18.5 million; the TTM figure through Dec 2025 stood at -$70.9 million (down 21.88% YoY), while the FY2025 annual figure was -$70.9 million, down 76.48% from the prior year.
  • EBITDA came in at -$18.5 million for Q4 2025 at SOPHiA GENETICS, down from -$17.9 million in the prior quarter.
  • In the past five years, EBITDA ranged from a high of -$9.1 million in Q4 2024 to a low of -$20502.0 billion in Q3 2021.
  • A 5-year average of -$1025.1 billion and a median of -$18.2 million in 2025 frame the typical range for EBITDA.
  • Across the five-year window, EBITDA plunged 217389460190.53% in 2021 and surged 100.0% in 2022, its largest moves.
  • SOPHiA GENETICS's EBITDA stood at -$21.0 million in 2021, then gained by 28.21% to -$15.1 million in 2022, then gained by 19.47% to -$12.1 million in 2023, then advanced by 25.49% to -$9.1 million in 2024, then sank by 104.57% to -$18.5 million in 2025.
  • According to Business Quant data, EBITDA over the past three periods registered -$18.5 million, -$17.9 million, and -$18.5 million for Q4 2025, Q3 2025, and Q2 2025 respectively.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBITDA (Qtr)
1 Veeva Systems 30.85 Bn 24.28 Bn 622.47 Mn 242.45 Mn
2 BrightSpring Health Services 12.29 Bn 11.41 Bn 482.22 Mn 121.45 Mn
3 Healthequity 7.80 Bn 7.48 Bn 256.31 Mn 102.95 Mn
4 Hinge Health 4.82 Bn 4.51 Bn 154.23 Mn 34.80 Mn
5 Doximity 4.21 Bn 3.46 Bn 125.97 Mn 24.83 Mn
6 Waystar Holding 4.18 Bn 4.03 Bn 268.04 Mn 87.47 Mn
7 10x Genomics 3.78 Bn 3.24 Bn 106.18 Mn -17.05 Mn
8 Privia Health 2.65 Bn 2.28 Bn 595.71 Mn 7.57 Mn
9 Omnicell 1.95 Bn 1.78 Bn 140.36 Mn 16.85 Mn
10 SOPHiA GENETICS 24.12 Mn -46.17 Mn 14.69 Mn -18.52 Mn

Historic Data

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DateValue
Dec 31, 2025 -18.52 Mn
Sep 30, 2025 -17.86 Mn
Jun 30, 2025 -18.49 Mn
Mar 31, 2025 -16.04 Mn
Dec 31, 2024 -9.05 Mn
Sep 30, 2024 -15.36 Mn
Jun 30, 2024 -15.01 Mn
Mar 31, 2024 -18.76 Mn
Dec 31, 2023 -12.15 Mn
Sep 30, 2023 -16.54 Mn
Jun 30, 2023 -20.05 Mn
Mar 31, 2023 -19.29 Mn
Dec 31, 2022 -15.08 Mn
Sep 30, 2022 -23.64 Mn
Jun 30, 2022 -24.08 Mn
Mar 31, 2022 -25.02 Mn
Dec 31, 2021 -21.01 Mn
Sep 30, 2021 -20.50 Mn
Jun 30, 2021 -15,924.00 Bn
Mar 31, 2021 -14.05 Mn
Dec 31, 2020 -11.29 Mn
Sep 30, 2020 -9.43 Bn
Jun 30, 2020 -7.04 Bn