Syndax Pharmaceuticals (SNDX) Gross Margin (2024 - 2026)

Syndax Pharmaceuticals' (SNDX) quarterly Gross Margin came in at 81.74% in Q1 2026, down 1385.0% year-on-year from 6.36% in Q1 2025, and down 34.64% quarter-over-quarter from 125.05% in Q4 2025.

Syndax Pharmaceuticals (SNDX) Gross Margin (2024 - 2026) Analysis & Trends

Syndax Pharmaceuticals' Gross Margin history runs 3 years deep, the most recent figure standing at 81.74% for Q1 2026.

  • On a quarterly basis, Gross Margin fell 1385.0% year-over-year to 81.74% in Q1 2026; TTM through Mar 2026 was 98.07%, a 199.0% increase from a year earlier, with the FY2025 full-year figure at 95.96%, down 56.0% from the prior year.
  • Gross Margin retreated to 81.74% in Q1 2026 per SNDX's latest filing, from 125.05% in the prior quarter.
  • Across five years, Gross Margin topped out at 125.05% in Q4 2025 and bottomed at 81.74% in Q1 2026.
  • The 3-year median for Gross Margin is 96.11% (2025), against an average of 96.27%.
  • Biggest YoY gain for Gross Margin was 3580 bps in 2025; the steepest drop was 1806 bps in 2025.
  • Year by year, Gross Margin stood at 89.24% in 2024, then jumped by 40 bps to 125.05% in 2025, then tumbled by 35 bps to 81.74% in 2026.
  • Per Business Quant, the three latest SNDX Gross Margin figures stand at 81.74% (Q1 2026), 125.05% (Q4 2025), and 81.94% (Q3 2025).

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Gross Margin (Qtr)
1 Oculis Holding AG 68,785.72 Bn 68,785.72 Bn - -
2 Nanobiotix 1,895.57 Bn 1,895.51 Bn - -
3 BeOne Medicines 471.35 Bn 466.56 Bn 1.35 Bn 88.95%
4 NuCana 279.75 Bn 279.75 Bn - -
5 Vertex Pharmaceuticals 120.24 Bn 113.00 Bn 2.59 Bn 86.85%
6 Regeneron Pharmaceuticals 67.80 Bn 59.04 Bn 3.31 Bn 91.79%
7 Belite Bio 62.51 Bn 62.51 Bn - -
8 Argenx Se 57.38 Bn 57.38 Bn 1.41 Bn 90.68%
9 Revolution Medicines 37.78 Bn 37.78 Bn - -
10 Syndax Pharmaceuticals 1.87 Bn 1.52 Bn 53.02 Mn 81.74%

Historic Data

Download Data
DateValue
Mar 31, 2026 81.74%
Dec 31, 2025 125.05%
Sep 30, 2025 81.94%
Jun 30, 2025 96.63%
Mar 31, 2025 95.58%
Dec 31, 2024 89.24%
Sep 30, 2024 100.00%
Jun 30, 2024 100.00%