Silence Therapeutics (SLN) Operating Margin (2024 - 2026)
Silence Therapeutics (SLN) recorded Operating Margin of -3729.15% in the quarter ended Mar 31, 2026, up 16277.19 percentage points from -20006.34% a year earlier and up 32920.85 percentage points from the prior quarter.
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Analysis
Silence Therapeutics (SLN) Operating Margin (2024 - 2026) Analysis & Trends
For the year ended Dec 31, 2025, Silence Therapeutics reported Operating Margin of -16292.84%, down 16146.47 percentage points from the prior year.
- Annual Operating Margin has a five-year change of -15638.58 percentage points (years ended Dec 2020 to Dec 2025).
- Across earlier years, Operating Margin came in at -146.38% in the year ended Dec 31, 2024 (+57.09 pp), -203.47% in the year ended Dec 31, 2023 (+78.41 pp), -281.87% in the year ended Dec 31, 2022 (+87.15 pp) and -369.02% in the year ended Dec 31, 2021 (+285.24 pp).
- The figure for the quarter ended Mar 31, 2026 is the highest quarterly Operating Margin since the quarter ended Dec 31, 2024.
- On a year-over-year basis, Operating Margin rose in 1 of the last five quarters, with an average year-over-year change of -12520.77 percentage points.
- Per Business Quant, the preceding three quarters came in at -36650.00% (quarter ended Dec 31, 2025), -16505.66% (quarter ended Sep 30, 2025) and -10697.77% (quarter ended Jun 30, 2025).
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Operating Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Johnson & Johnson | 655.56 Bn | 574.09 Bn | 17.26 Bn | 28.21% |
| 2 | AbbVie | 470.94 Bn | 444.10 Bn | 12.70 Bn | 37.86% |
| 3 | Merck | 367.14 Bn | 321.57 Bn | 12.21 Bn | -3.52% |
| 4 | Novartis Ag | 280.33 Bn | 236.20 Bn | 11.24 Bn | 32.97% |
| 5 | Astrazeneca | 257.78 Bn | 231.34 Bn | 12.86 Bn | 20.57% |
| 6 | Amgen | 226.04 Bn | 181.44 Bn | 7.24 Bn | 34.95% |
| 7 | Gilead Sciences | 188.89 Bn | 163.01 Bn | 6.22 Bn | -133.21% |
| 8 | Pfizer | 163.75 Bn | 110.70 Bn | 10.94 Bn | 28.37% |
| 9 | Vertex Pharmaceuticals | 133.68 Bn | 105.69 Bn | 2.84 Bn | 37.40% |
| 10 | Silence Therapeutics | 529.16 Mn | 457.06 Mn | - | - |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Mar 31, 2026 | -3,729.15% |
| Dec 31, 2025 | -36,650.00% |
| Sep 30, 2025 | -16,505.66% |
| Jun 30, 2025 | -10,697.77% |
| Mar 31, 2025 | -20,006.34% |
| Dec 31, 2024 | -17.20% |
| Sep 30, 2024 | -2,002.47% |
| Jun 30, 2024 | -2,923.50% |
| Mar 31, 2024 | -35.55% |
API Access
Silence Therapeutics Operating Margin API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=operating-margin&ticker=SLN&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "operating-margin", "ticker": "SLN", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=operating-margin&ticker=SLN&period=max&api_key=YOUR_API_KEY");
const data = await res.json();