Silence Therapeutics (SLN) Gross Margin (2020 - 2026)
Silence Therapeutics (SLN) recorded Gross Margin of 97.39% in the quarter ended Mar 31, 2026, up 35.42 percentage points from 61.97% a year earlier and up 32.69 percentage points from the prior quarter.
Powered by 
Analysis
Silence Therapeutics (SLN) Gross Margin (2020 - 2026) Analysis & Trends
For the year ended Dec 31, 2025, Silence Therapeutics reported Gross Margin of 61.54%, down 11.16 percentage points from the prior year.
- Annual Gross Margin has a five-year change of +30.20 percentage points (years ended Dec 2020 to Dec 2025).
- Across earlier years, Gross Margin came in at 72.70% in the year ended Dec 31, 2024 (+13.36 pp), 59.34% in the year ended Dec 31, 2023 (+21.51 pp), 37.83% in the year ended Dec 31, 2022 (-2.11 pp) and 39.94% in the year ended Dec 31, 2021 (+8.61 pp).
- The figure for the quarter ended Mar 31, 2026 is the highest quarterly Gross Margin in data going back to the quarter ended Mar 31, 2024.
- On a year-over-year basis, Gross Margin rose in three of the last five quarters, with an average year-over-year change of +114.97 percentage points.
- Per Business Quant, the preceding three quarters came in at 64.71% (quarter ended Dec 31, 2025), 59.75% (quarter ended Sep 30, 2025) and 62.05% (quarter ended Jun 30, 2025).
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Gross Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Eli Lilly | 1,348.13 Bn | 1,321.74 Bn | 20.46 Bn | 83.88% |
| 2 | Johnson & Johnson | 675.90 Bn | 595.76 Bn | 17.30 Bn | 68.12% |
| 3 | AbbVie | 519.45 Bn | 487.50 Bn | 13.12 Bn | 75.38% |
| 4 | Merck | 364.95 Bn | 327.95 Bn | 13.19 Bn | 72.95% |
| 5 | Novartis Ag | 311.58 Bn | 285.16 Bn | - | - |
| 6 | Astrazeneca | 289.34 Bn | 262.94 Bn | 13.26 Bn | 88.03% |
| 7 | Amgen | 251.64 Bn | 203.30 Bn | 7.58 Bn | 73.10% |
| 8 | Gilead Sciences | 212.05 Bn | 187.07 Bn | 6.73 Bn | 81.07% |
| 9 | Pfizer | 167.35 Bn | 115.00 Bn | 12.56 Bn | 75.71% |
| 10 | Silence Therapeutics | 935.01 Mn | 862.91 Mn | - | - |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Mar 31, 2026 | 97.39% |
| Dec 31, 2025 | 64.71% |
| Sep 30, 2025 | 59.75% |
| Jun 30, 2025 | 62.05% |
| Mar 31, 2025 | 61.97% |
| Dec 31, 2024 | 91.95% |
| Sep 30, 2024 | -142.92% |
| Jun 30, 2024 | -322.13% |
| Mar 31, 2024 | 82.16% |
| Dec 31, 2023 | 35.87% |
| Sep 30, 2023 | 42.57% |
| Jun 30, 2023 | 68.90% |
| Mar 31, 2023 | 60.14% |
| Dec 31, 2022 | 19.01% |
| Sep 30, 2022 | 28.98% |
| Jun 30, 2022 | 35.44% |
| Mar 31, 2022 | 60.24% |
| Dec 31, 2021 | 40.19% |
| Sep 30, 2021 | 34.98% |
| Jun 30, 2021 | 32.43% |
API Access
Silence Therapeutics Gross Margin API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=gross-margin&ticker=SLN&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "gross-margin", "ticker": "SLN", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=gross-margin&ticker=SLN&period=max&api_key=YOUR_API_KEY");
const data = await res.json();