Silence Therapeutics (SLN) Gross Margin (2024 - 2026)

Silence Therapeutics (SLN) posted Gross Margin of 97.39% for Q1 2026, up 50.52% sequentially from 64.71% in Q4 2025, and up 3542.0% YoY from 2.67% in Q1 2025.

Silence Therapeutics (SLN) Gross Margin (2024 - 2026) Analysis & Trends

Silence Therapeutics has reported Gross Margin for 3 years, with the latest figure at 97.39% in Q1 2026.

  • Quarterly Gross Margin rose 3542.0% year-over-year to 97.39% in Q1 2026, while the trailing twelve-month figure through Mar 2026 was 79.5% (up 1233.0% YoY) and the FY2025 annual result came in at 61.54%, down 1116.0% from the prior year.
  • Gross Margin advanced to 97.39% in Q1 2026 per SLN's latest filing, from 64.71% in the prior quarter.
  • Over five years, Gross Margin peaked at 97.39% in Q1 2026 and troughed at 322.12% in Q2 2024.
  • A 3-year average of 6.1% and a median of 62.05% in 2025 frame the typical range for Gross Margin.
  • The widest YoY moves for Gross Margin: up 38418 bps in 2025, down 2724 bps in 2025.
  • Over 3 years, Gross Margin stood at 91.95% in 2024, then decreased by 30 bps to 64.71% in 2025, then soared by 51 bps to 97.39% in 2026.
  • According to Business Quant data, Gross Margin over the past three periods registered 97.39%, 64.71%, and 59.75% for Q1 2026, Q4 2025, and Q3 2025 respectively.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Gross Margin (Qtr)
1 Vertex Pharmaceuticals 128.13 Bn 120.28 Bn 2.84 Bn 85.33%
2 Regeneron Pharmaceuticals 112.33 Bn 104.33 Bn 3.93 Bn 91.59%
3 Argenx Se 53.24 Bn 48.05 Bn 1.41 Bn 90.68%
4 Revolution Medicines 43.64 Bn 43.64 Bn - -
5 BeOne Medicines 39.27 Bn 34.17 Bn 1.53 Bn 89.76%
6 MindWalk Holdings 35.32 Bn 35.31 Bn 1.82 Bn 60,631,834.75%
7 Royalty Pharma 33.72 Bn 35.84 Bn - -
8 Alnylam Pharmaceuticals 30.58 Bn 27.27 Bn 992.69 Mn 76.90%
9 Insmed 27.01 Bn 25.85 Bn 358.27 Mn 84.20%
10 Silence Therapeutics 648.22 Mn 576.12 Mn - -

Historic Data

Download Data
DateValue
Mar 31, 2026 97.39%
Dec 31, 2025 64.71%
Sep 30, 2025 59.75%
Jun 30, 2025 62.05%
Mar 31, 2025 61.97%
Dec 31, 2024 91.95%
Sep 30, 2024 -142.92%
Jun 30, 2024 -322.13%
Mar 31, 2024 82.16%