Silence Therapeutics (SLN) Gross Margin (2024 - 2026)
Silence Therapeutics (SLN) recorded Gross Margin of 97.39% in the quarter ended Mar 31, 2026, up 35.42 percentage points from 61.97% a year earlier and up 32.69 percentage points from the prior quarter.
Silence Therapeutics (SLN) Gross Margin (2024 - 2026) Analysis & Trends
For the year ended Dec 31, 2025, Silence Therapeutics reported Gross Margin of 61.54%, down 11.16 percentage points from the prior year.
- Annual Gross Margin has a five-year change of +30.20 percentage points (years ended Dec 2020 to Dec 2025).
- Across earlier years, Gross Margin came in at 72.70% in the year ended Dec 31, 2024 (+13.36 pp), 59.34% in the year ended Dec 31, 2023 (+21.51 pp), 37.83% in the year ended Dec 31, 2022 (-2.11 pp) and 39.94% in the year ended Dec 31, 2021 (+8.61 pp).
- The figure for the quarter ended Mar 31, 2026 is the highest quarterly Gross Margin in data going back to the quarter ended Mar 31, 2024.
- On a year-over-year basis, Gross Margin rose in three of the last five quarters, with an average year-over-year change of +114.97 percentage points.
- Per Business Quant, the preceding three quarters came in at 64.71% (quarter ended Dec 31, 2025), 59.75% (quarter ended Sep 30, 2025) and 62.05% (quarter ended Jun 30, 2025).
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Gross Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Johnson & Johnson | 655.56 Bn | 574.09 Bn | 17.26 Bn | 68.19% |
| 2 | AbbVie | 470.94 Bn | 444.10 Bn | 12.70 Bn | 74.74% |
| 3 | Merck | 367.14 Bn | 321.57 Bn | 12.21 Bn | 73.54% |
| 4 | Novartis Ag | 280.33 Bn | 236.20 Bn | 11.24 Bn | 78.02% |
| 5 | Astrazeneca | 257.78 Bn | 231.34 Bn | 12.86 Bn | 83.60% |
| 6 | Amgen | 226.04 Bn | 181.44 Bn | 7.24 Bn | 72.04% |
| 7 | Gilead Sciences | 188.89 Bn | 163.01 Bn | 6.22 Bn | 79.76% |
| 8 | Pfizer | 163.75 Bn | 110.70 Bn | 10.94 Bn | 72.78% |
| 9 | Vertex Pharmaceuticals | 133.68 Bn | 105.69 Bn | 2.84 Bn | 85.33% |
| 10 | Silence Therapeutics | 529.16 Mn | 457.06 Mn | - | - |
Historic Data
| Date | Value |
|---|---|
| Mar 31, 2026 | 97.39% |
| Dec 31, 2025 | 64.71% |
| Sep 30, 2025 | 59.75% |
| Jun 30, 2025 | 62.05% |
| Mar 31, 2025 | 61.97% |
| Dec 31, 2024 | 91.95% |
| Sep 30, 2024 | -142.92% |
| Jun 30, 2024 | -322.13% |
| Mar 31, 2024 | 82.16% |
Silence Therapeutics Gross Margin API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=gross-margin&ticker=SLN&period=max&api_key=YOUR_API_KEY
import requests
url = "https://data.businessquant.com/historic"
params = {"slug": "gross-margin", "ticker": "SLN", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()
const res = await fetch("https://data.businessquant.com/historic?slug=gross-margin&ticker=SLN&period=max&api_key=YOUR_API_KEY");
const data = await res.json();