Growth Metrics

Silence Therapeutics (SLN) Gross Margin (2020 - 2026)

Silence Therapeutics recorded quarterly Gross Margin of 97.39% in Q1 2026, up 50.52% quarter-over-quarter from 64.71% in Q4 2025, and up 3542.0% year-over-year from 2.67% in Q1 2025.

Silence Therapeutics' Gross Margin history runs 7 years deep, the most recent figure standing at 97.39% for Q1 2026.

  • In Q1 2026, Gross Margin rose 3542.0% year-over-year to 97.39%; the TTM figure through Mar 2026 stood at 81.84% (up 1456.0% YoY), while the FY2025 annual figure was 61.54%, down 1116.0% from the prior year.
  • Gross Margin came in at 97.39% for Q1 2026 at Silence Therapeutics, up from 64.71% in the prior quarter.
  • In the past five years, Gross Margin ranged from a high of 97.39% in Q1 2026 to a low of 340.87% in Q2 2024.
  • A 5-year average of 23.22% and a median of 60.14% in 2023 frame the typical range for Gross Margin.
  • On a YoY basis, Gross Margin climbed as much as 2000000000 bps in 2022 and fell as far as 2000000000 bps in 2022.
  • Silence Therapeutics' Gross Margin stood at 19.01% in 2022, then surged by 89 bps to 35.87% in 2023, then jumped by 156 bps to 91.95% in 2024, then retreated by 30 bps to 64.71% in 2025, then surged by 51 bps to 97.39% in 2026.
  • According to Business Quant data, Gross Margin over the past three periods registered 97.39%, 64.71%, and 59.75% for Q1 2026, Q4 2025, and Q3 2025 respectively.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Gross Margin (Qtr)
1 Quantum Biopharma 961,148.99 Bn 961,148.98 Bn - -
2 Alterity Therapeutics 744,933.29 Bn 744,933.26 Bn - -
3 Legend Biotech 2,540.00 Bn 2,539.71 Bn 242.10 Mn 79.04%
4 Nanobiotix 2,199.85 Bn 2,199.78 Bn - -
5 Akari Therapeutics 1,635.88 Bn 1,635.88 Bn - -
6 Vertex Pharmaceuticals 111.32 Bn 104.07 Bn 2.59 Bn 86.85%
7 Evaxion A 62.56 Bn 62.54 Bn - -
8 Regeneron Pharmaceuticals 62.55 Bn 53.79 Bn 3.31 Bn 91.79%
9 Alnylam Pharmaceuticals 39.57 Bn 36.56 Bn 959.66 Mn 82.22%
10 Silence Therapeutics 924.61 Mn 854.53 Mn 411,000.00 97.39%

Historic Data

Download Data 🔒
DateValue
Mar 31, 2026 97.39%
Dec 31, 2025 64.71%
Sep 30, 2025 59.75%
Jun 30, 2025 69.50%
Mar 31, 2025 61.97%
Dec 31, 2024 91.95%
Sep 30, 2024 -142.92%
Jun 30, 2024 -340.87%
Mar 31, 2024 82.16%
Dec 31, 2023 35.87%
Sep 30, 2023 42.57%
Jun 30, 2023 68.90%
Mar 31, 2023 60.14%
Dec 31, 2022 19.01%
Sep 30, 2022 28.98%
Jun 30, 2022 35.44%
Mar 31, 2022 60.24%
Dec 31, 2021 -105,067,224.40%
Sep 30, 2021 34,980,988.59%
Jun 30, 2021 32.43%
Mar 31, 2021 51.11%
Dec 31, 2020 31.34%
Sep 30, 2020 -17,253,521.13%