Sera Prognostics (SERA) Operating Margin (2020 - 2026)
Sera Prognostics (SERA) reported Operating Margin of -33346.67% for Q2 2026, up 21476.86 percentage points from -54823.53% a year earlier and up 33510.48 percentage points from the prior quarter.
Sera Prognostics (SERA) Operating Margin (2020 - 2026) Analysis & Trends
Over the twelve months ended Jun 30, 2026, Sera Prognostics' Operating Margin came in at -53282.86%, down 19157.86 percentage points year-over-year; for FY2025, it came in at -45066.67%, up 2511.26 percentage points from FY2024.
- Operating Margin has a five-year change of +26817.33 percentage points (FY2020 to FY2025).
- By year, Operating Margin came in at -47577.92% in FY2024 (-34564.52 pp), -13013.40% in FY2023 (+4020.93 pp), -17034.33% in FY2022 (+26130.31 pp) and -43164.63% in FY2021 (+28719.37 pp).
- The Q2 2026 figure ranks as the highest quarterly Operating Margin since Q1 2025.
- Year over year, Operating Margin gained in 1 of the last seven quarters, with an average year-over-year change of -20272.33 percentage points.
- The high point for year-over-year Operating Margin in five years was Q3 2021 (a gain of 51827.83 percentage points); the low point was Q4 2025 (a drop of 50277.50 percentage points).
- Per Business Quant data, the three quarters before Q2 2026 came in at -66857.14% (Q1 2026), -89540.00% (Q4 2025) and -56125.00% (Q3 2025).
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Operating Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | HCA Healthcare | 94.29 Bn | 93.74 Bn | - | - |
| 2 | Natera | 59.14 Bn | 54.82 Bn | 485.19 Mn | -10.07% |
| 3 | Quest Diagnostics | 26.23 Bn | 24.66 Bn | 1.03 Bn | 15.08% |
| 4 | Labcorp Holdings | 25.04 Bn | 22.81 Bn | 1.11 Bn | 12.10% |
| 5 | Guardant Health | 23.69 Bn | 19.76 Bn | 219.03 Mn | -38.55% |
| 6 | Tenet Healthcare | 20.77 Bn | 11.92 Bn | - | 26.67% |
| 7 | Tempus AI | 14.91 Bn | 11.94 Bn | 246.50 Mn | -19.85% |
| 8 | Encompass Health | 12.24 Bn | 12.70 Bn | - | - |
| 9 | Davita | 11.39 Bn | 10.15 Bn | 1.16 Bn | 16.29% |
| 10 | Sera Prognostics | 101.96 Mn | 101.96 Mn | -20,000.00 | -33,346.67% |
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | -33,346.67% |
| Mar 31, 2026 | -66,857.14% |
| Dec 31, 2025 | -89,540.00% |
| Sep 30, 2025 | -56,125.00% |
| Jun 30, 2025 | -54,823.53% |
| Mar 31, 2025 | -24,342.11% |
| Dec 31, 2024 | -39,262.50% |
| Sep 30, 2024 | -30,558.62% |
| Jun 30, 2024 | -38,554.17% |
| Dec 31, 2023 | -21,580.49% |
| Sep 30, 2023 | -19,485.71% |
| Jun 30, 2023 | -9,317.07% |
| Mar 31, 2023 | -11,329.00% |
| Dec 31, 2022 | -16,027.69% |
| Sep 30, 2022 | -12,859.77% |
| Jun 30, 2022 | -15,058.97% |
| Mar 31, 2022 | -32,368.42% |
| Dec 31, 2021 | -48,257.69% |
| Sep 30, 2021 | -41,052.17% |
| Jun 30, 2021 | -36,905.00% |
Sera Prognostics Operating Margin API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=operating-margin&ticker=SERA&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "operating-margin", "ticker": "SERA", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=operating-margin&ticker=SERA&period=max&api_key=YOUR_API_KEY");
const data = await res.json();