Sera Prognostics (SERA) Operating Margin (2020 - 2026)

Sera Prognostics filings provide 6 years of Operating Margin readings, the most recent being 89540.0% for Q4 2025.

  • On a quarterly basis, Operating Margin fell 5027750.0% to 89540.0% in Q4 2025 year-over-year; TTM through Dec 2025 was 45066.67%, a 251126.0% increase, with the full-year FY2025 number at 45066.67%, up 251126.0% from a year prior.
  • Operating Margin hit 89540.0% in Q4 2025 for Sera Prognostics, down from 56125.0% in the prior quarter.
  • In the past five years, Operating Margin ranged from a high of 9317.07% in Q2 2023 to a low of 89540.0% in Q4 2025.
  • Median Operating Margin over the past 5 years was 32368.42% (2022), compared with a mean of 33883.9%.
  • Biggest five-year swings in Operating Margin: skyrocketed 5182783bps in 2021 and later crashed -5027750bps in 2025.
  • Sera Prognostics' Operating Margin stood at 48257.69% in 2021, then surged by 67bps to 16027.69% in 2022, then crashed by -35bps to 21580.49% in 2023, then crashed by -82bps to 39262.5% in 2024, then tumbled by -128bps to 89540.0% in 2025.
  • The last three reported values for Operating Margin were 89540.0% (Q4 2025), 56125.0% (Q3 2025), and 54823.53% (Q2 2025) per Business Quant data.