Sera Prognostics (SERA) Operating Margin (2020 - 2026)
Sera Prognostics' (SERA) quarterly Operating Margin came in at 33346.67% in Q2 2026, up 2147686.0% on a YoY basis from N/an in Q2 2025, and up 50.12% quarter-over-quarter from 66857.14% in Q1 2026.
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Sera Prognostics (SERA) Operating Margin (2020 - 2026) Analysis & Trends
Sera Prognostics (SERA) has reported Operating Margin for 7 consecutive years, with 33346.67% the latest figure, recorded in Q2 2026.
- For the quarter ending Q2 2026, Operating Margin rose 2147686.0% year-over-year to 33346.67%; the trailing twelve-month figure through Jun 2026 stood at 53282.86% (down 1915786.0% YoY), and the FY2025 full-year result was 45066.67%, up 251126.0% from the prior year.
- Operating Margin rose to 33346.67% in Q2 2026 per SERA's latest filing, from 66857.14% in the prior quarter.
- Across five years, Operating Margin topped out at 9317.07% in Q2 2023 and bottomed at 89540.0% in Q4 2025.
- Historically, Operating Margin has averaged 33613.93% across 5 years, with a median of 30558.62% in 2024.
- The sharpest annual moves came in 2022 and 2025: Operating Margin soared 3223000 bps in 2022, then slumped 5027750 bps in 2025.
- Over 5 years, Operating Margin stood at 16027.69% in 2022, then slumped by 35 bps to 21580.49% in 2023, then sank by 82 bps to 39262.5% in 2024, then plunged by 128 bps to 89540.0% in 2025, then surged by 63 bps to 33346.67% in 2026.
- According to Business Quant data, Operating Margin over the past three periods registered 33346.67%, 66857.14%, and 89540.0% for Q2 2026, Q1 2026, and Q4 2025 respectively.
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Operating Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Natera | 47.12 Bn | 46.02 Bn | 486.15 Mn | -10.07% |
| 2 | Labcorp Holdings | 26.25 Bn | 26.10 Bn | 1.11 Bn | 12.10% |
| 3 | Quest Diagnostics | 26.02 Bn | 25.40 Bn | 1.03 Bn | 15.08% |
| 4 | Guardant Health | 21.89 Bn | 20.84 Bn | 219.03 Mn | -38.55% |
| 5 | Tempus AI | 11.21 Bn | 10.39 Bn | 274.25 Mn | -19.85% |
| 6 | Caris Life Sciences | 6.94 Bn | 6.14 Bn | 182.38 Mn | 10.21% |
| 7 | Sotera Health | 5.22 Bn | 4.86 Bn | 177.96 Mn | 34.17% |
| 8 | BillionToOne | 4.75 Bn | 4.20 Bn | 77.11 Mn | 5.03% |
| 9 | iRhythm Holdings | 3.98 Bn | 3.39 Bn | 163.21 Mn | -1.13% |
| 10 | Sera Prognostics | 103.48 Mn | 103.48 Mn | -20,000.00 | -33,346.67% |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | -33,346.67% |
| Mar 31, 2026 | -66,857.14% |
| Dec 31, 2025 | -89,540.00% |
| Sep 30, 2025 | -56,125.00% |
| Jun 30, 2025 | -54,823.53% |
| Mar 31, 2025 | -24,342.11% |
| Dec 31, 2024 | -39,262.50% |
| Sep 30, 2024 | -30,558.62% |
| Jun 30, 2024 | -38,554.17% |
| Dec 31, 2023 | -21,580.49% |
| Sep 30, 2023 | -19,485.71% |
| Jun 30, 2023 | -9,317.07% |
| Mar 31, 2023 | -11,329.00% |
| Dec 31, 2022 | -16,027.69% |
| Sep 30, 2022 | -12,859.77% |
| Jun 30, 2022 | -15,058.97% |
| Mar 31, 2022 | -32,368.42% |
| Dec 31, 2021 | -48,257.69% |
| Sep 30, 2021 | -41,052.17% |
| Jun 30, 2021 | -36,905.00% |