Septerna (SEPN) Net Margin (2023 - 2026)
Septerna (SEPN) recorded quarterly Net Margin of 32.59% in Q1 2026, up 26.8% quarter-over-quarter from 44.52% in Q4 2025, and up 977380.0% on a YoY basis from N/an in Q1 2025.
Septerna (SEPN) Net Margin (2023 - 2026) Analysis & Trends
Septerna's Net Margin history runs 4 years deep, the most recent figure standing at 32.59% for Q1 2026.
- In Q1 2026, Net Margin rose 977380.0% year-over-year to 32.59%; the TTM figure through Mar 2026 stood at 49.89% (up 806945.0% YoY), while the FY2025 annual figure was 106.37%, up 657251.0% from the prior year.
- Net Margin was 32.59% for Q1 2026 at Septerna, up from 44.52% in the prior quarter.
- In the past five years, Net Margin ranged from a high of 38.02% in Q3 2025 to a low of 33166.67% in Q3 2023.
- Historically, Net Margin has averaged 9973.46% across 4 years, with a median of 9749.06% in 2024.
- The sharpest annual moves came in 2024 and 2025: Net Margin soared 2150587 bps in 2024, then sank 1636984 bps in 2025.
- A 4-year view of Net Margin shows it stood at 15383.9% in 2023, then jumped by 37 bps to 9749.06% in 2024, then surged by 100 bps to 44.52% in 2025, then increased by 27 bps to 32.59% in 2026.
- The last three Net Margin figures came in at 32.59% (Q1 2026), 44.52% (Q4 2025), and 38.02% (Q3 2025), per Business Quant data.
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Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Net Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Alterity Therapeutics | 925,601.88 Bn | 925,601.85 Bn | - | - |
| 2 | Belite Bio | 58,560.00 Bn | 58,560.00 Bn | - | - |
| 3 | Quantum Biopharma | 17,284.41 Bn | 17,284.40 Bn | - | - |
| 4 | Legend Biotech | 2,809.00 Bn | 2,808.71 Bn | 242.10 Mn | 0.82% |
| 5 | Evaxion A | 1,334.43 Bn | 1,334.42 Bn | - | - |
| 6 | Akari Therapeutics | 1,312.27 Bn | 1,312.26 Bn | - | - |
| 7 | Psyence Biomedical | 212.16 Bn | 212.16 Bn | - | - |
| 8 | Vertex Pharmaceuticals | 114.83 Bn | 107.58 Bn | 2.59 Bn | 34.53% |
| 9 | Abivax | 91.96 Bn | 91.96 Bn | - | - |
| 10 | Septerna | 1.62 Bn | 1.62 Bn | - | -32.59% |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -32.59% |
| Dec 31, 2025 | -44.52% |
| Sep 30, 2025 | 38.02% |
| Jun 30, 2025 | -20,872.27% |
| Mar 31, 2025 | -9,806.39% |
| Dec 31, 2024 | -9,749.06% |
| Sep 30, 2024 | -11,660.80% |
| Jun 30, 2024 | -4,502.43% |
| Mar 31, 2024 | -4,527.44% |
| Dec 31, 2023 | -15,383.90% |
| Sep 30, 2023 | -33,166.67% |