Septerna (SEPN) Net Margin (2023 - 2026)
Septerna's quarterly Net Margin came in at 32.59% in Q1 2026, up 977380.0% year-on-year from N/an in Q1 2025, and up 26.8% quarter-over-quarter from 44.52% in Q4 2025.
Septerna has reported Net Margin for 4 years, with the latest figure at 32.59% in Q1 2026.
- For the quarter ending Q1 2026, Net Margin rose 977380.0% year-over-year to 32.59%; the trailing twelve-month figure through Mar 2026 stood at 49.89% (up 806945.0% YoY), and the FY2025 full-year result was 106.37%, up 657251.0% from the prior year.
- Net Margin for Q1 2026 stood at 32.59%, up from 44.52% in the prior quarter.
- The five-year high for Net Margin was 38.02% in Q3 2025, with the low at 33166.67% in Q3 2023.
- Average Net Margin over 4 years is 9973.46%, with a median of 9749.06% recorded in 2024.
- Year-over-year, Net Margin surged 2150587 bps in 2024 and sank 1636984 bps in 2025.
- Tracing SEPN's Net Margin over 4 years: stood at 15383.9% in 2023, then surged by 37 bps to 9749.06% in 2024, then soared by 100 bps to 44.52% in 2025, then rose by 27 bps to 32.59% in 2026.
- The last three Net Margin figures came in at 32.59% (Q1 2026), 44.52% (Q4 2025), and 38.02% (Q3 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Net Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Quantum Biopharma | 961,148.99 Bn | 961,148.98 Bn | - | - |
| 2 | Alterity Therapeutics | 744,933.29 Bn | 744,933.26 Bn | - | - |
| 3 | Legend Biotech | 2,540.00 Bn | 2,539.71 Bn | 242.10 Mn | 0.82% |
| 4 | Nanobiotix | 2,199.85 Bn | 2,199.78 Bn | - | - |
| 5 | Akari Therapeutics | 1,635.88 Bn | 1,635.88 Bn | - | - |
| 6 | Vertex Pharmaceuticals | 111.32 Bn | 104.07 Bn | 2.59 Bn | 34.53% |
| 7 | Evaxion A | 62.56 Bn | 62.54 Bn | - | - |
| 8 | Regeneron Pharmaceuticals | 62.55 Bn | 53.79 Bn | 3.31 Bn | 20.17% |
| 9 | Alnylam Pharmaceuticals | 39.57 Bn | 36.56 Bn | 959.66 Mn | 17.65% |
| 10 | Septerna | 1.34 Bn | 1.34 Bn | - | -32.59% |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -32.59% |
| Dec 31, 2025 | -44.52% |
| Sep 30, 2025 | 38.02% |
| Jun 30, 2025 | -20,872.27% |
| Mar 31, 2025 | -9,806.39% |
| Dec 31, 2024 | -9,749.06% |
| Sep 30, 2024 | -11,660.80% |
| Jun 30, 2024 | -4,502.43% |
| Mar 31, 2024 | -4,527.44% |
| Dec 31, 2023 | -15,383.90% |
| Sep 30, 2023 | -33,166.67% |