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Asset Utilization RatioAssets AverageEBIT MarginEBITDA MarginEBT MarginEnterprise ValueEquity AverageEquity RatioFCF MarginInvested CapitalNet MarginOperating MarginReturn on AssetsReturn on Capital EmployedReturn on EquityReturn on Invested CapitalReturn on Sales

Septerna (SEPN) Net Margin (2023 - 2025)

Septerna (SEPN) has 3 years of Net Margin data on record, last reported at 196.33% in Q4 2025.

  • For Q4 2025, Net Margin rose 994444.0% year-over-year to 196.33%; the TTM value through Dec 2025 reached 20.04%, up 673632.0%, while the annual FY2025 figure was 20.17%, 669887.0% up from the prior year.
  • Net Margin reached 196.33% in Q4 2025 per SEPN's latest filing, up from 38.02% in the prior quarter.
  • Across five years, Net Margin topped out at 196.33% in Q4 2025 and bottomed at 33166.67% in Q3 2023.
  • Average Net Margin over 3 years is 10449.97%, with a median of 9748.11% recorded in 2024.
  • Peak YoY movement for Net Margin: soared 2150587bps in 2024, then crashed -1636984bps in 2025.
  • A 3-year view of Net Margin shows it stood at 33166.67% in 2023, then soared by 71bps to 9748.11% in 2024, then soared by 102bps to 196.33% in 2025.
  • Per Business Quant database, its latest 3 readings for Net Margin were 196.33% in Q4 2025, 38.02% in Q3 2025, and 20872.27% in Q2 2025.