Balance Sheet
Cash Flow Statement
Daily Values
Growth Metrics
Income Statement
Others
Ratios
Asset Utilization RatioAssets AverageEBIT MarginEBITDA MarginEBT MarginEnterprise ValueEquity AverageEquity RatioFCF MarginInvested CapitalNet MarginOperating MarginReturn on AssetsReturn on Capital EmployedReturn on EquityReturn on Invested CapitalReturn on Sales

Septerna (SEPN) Net Margin (2023 - 2025)

Septerna has reported Net Margin over the past 3 years, most recently at 44.52% for Q4 2025.

  • Quarterly results put Net Margin at 44.52% for Q4 2025, up 993614.0% from a year ago — trailing twelve months through Dec 2025 was 106.37% (up 665577.0% YoY), and the annual figure for FY2025 was 106.37%, up 661819.0%.
  • Net Margin for Q4 2025 was 44.52% at Septerna, down from 38.02% in the prior quarter.
  • Over the last five years, Net Margin for SEPN hit a ceiling of 38.02% in Q3 2025 and a floor of 33166.67% in Q3 2023.
  • Median Net Margin over the past 3 years was 9893.53% (2025), compared with a mean of 10990.71%.
  • Biggest five-year swings in Net Margin: surged 2150587bps in 2024 and later tumbled -1636984bps in 2025.
  • Septerna's Net Margin stood at 15383.9% in 2023, then soared by 35bps to 9980.66% in 2024, then skyrocketed by 100bps to 44.52% in 2025.
  • The last three reported values for Net Margin were 44.52% (Q4 2025), 38.02% (Q3 2025), and 20872.27% (Q2 2025) per Business Quant data.