Septerna (SEPN) Net Cash Flow (2023 - 2026)

Septerna's Net Cash Flow history runs 4 years deep, the most recent figure standing at -$49.1 million for Q1 2026.

• On a quarterly basis, Net Cash Flow fell 74.48% year-over-year to -$49.1 million in Q1 2026; TTM through Mar 2026 was -$138.4 million, a 357.55% decrease from a year earlier, with the FY2025 full-year figure at -$117.5 million, down 178.47% from the prior year.
• Net Cash Flow rose to -$49.1 million in Q1 2026 per SEPN's latest filing, from -$199.3 million in the prior quarter.
• Across five years, Net Cash Flow topped out at $150.0 million in Q4 2024 and bottomed at -$199.3 million in Q4 2025.
• The 4-year median for Net Cash Flow is -$22.9 million (2024), against an average of -$10.2 million.
• Across the five-year window, Net Cash Flow jumped 1594.16% in 2024 and sank 294.11% in 2025, its largest moves.
• Year by year, Net Cash Flow stood at -$10.0 million in 2023, then soared by 1594.16% to $150.0 million in 2024, then sank by 232.89% to -$199.3 million in 2025, then surged by 75.35% to -$49.1 million in 2026.
• Per Business Quant, the three latest SEPN Net Cash Flow figures stand at -$49.1 million (Q1 2026), -$199.3 million (Q4 2025), and $130.7 million (Q3 2025).