Balance Sheet
Cash Flow Statement
Amortizatization of IntangiblesCapital ExpendituresCash from Financing ActivitiesCash from Investing ActivitiesCash from OperationsChange in Account PayablesChange in Accured ExpensesChange in Acquisitions & DivestmentsChange in CashChange in ReceivablesDepreciation & Amortization (CF)Free Cash FlowGains from Investment SecuritiesGains from Sales and DivestituresNet Cash FlowNet IncomeNon-cash ItemsShare-based CompensationShares Issued
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Septerna (SEPN) Net Cash Flow (2023 - 2025)

Septerna has reported Net Cash Flow over the past 3 years, most recently at -$199.3 million for Q4 2025.

  • Quarterly results put Net Cash Flow at -$199.3 million for Q4 2025, down 232.89% from a year ago — trailing twelve months through Dec 2025 was -$117.5 million (down 257.13% YoY), and the annual figure for FY2025 was -$117.5 million, down 178.47%.
  • Net Cash Flow for Q4 2025 was -$199.3 million at Septerna, down from $130.7 million in the prior quarter.
  • Over the last five years, Net Cash Flow for SEPN hit a ceiling of $150.0 million in Q4 2024 and a floor of -$199.3 million in Q4 2025.
  • Median Net Cash Flow over the past 3 years was -$20.7 million (2025), compared with a mean of -$5.9 million.
  • Biggest five-year swings in Net Cash Flow: skyrocketed 1594.16% in 2024 and later crashed 294.11% in 2025.
  • Septerna's Net Cash Flow stood at -$10.0 million in 2023, then skyrocketed by 1594.16% to $150.0 million in 2024, then tumbled by 232.89% to -$199.3 million in 2025.
  • The last three reported values for Net Cash Flow were -$199.3 million (Q4 2025), $130.7 million (Q3 2025), and -$20.7 million (Q2 2025) per Business Quant data.