Septerna (SEPN) Free Cash Flow (2023 - 2025)

Septerna has reported Free Cash Flow over the past 3 years, most recently at -$15.1 million for Q4 2025.

  • Quarterly results put Free Cash Flow at -$15.1 million for Q4 2025, up 30.21% from a year ago — trailing twelve months through Dec 2025 was $109.7 million (up 257.63% YoY), and the annual figure for FY2025 was $109.7 million, up 257.63%.
  • Free Cash Flow for Q4 2025 was -$15.1 million at Septerna, down from $168.8 million in the prior quarter.
  • Over the last five years, Free Cash Flow for SEPN hit a ceiling of $168.8 million in Q3 2025 and a floor of -$23.7 million in Q1 2025.
  • Median Free Cash Flow over the past 3 years was -$17.4 million (2024), compared with a mean of $3.3 million.
  • Biggest five-year swings in Free Cash Flow: tumbled 114.93% in 2024 and later surged 1070.53% in 2025.
  • Septerna's Free Cash Flow stood at -$10.0 million in 2023, then tumbled by 114.93% to -$21.6 million in 2024, then soared by 30.21% to -$15.1 million in 2025.
  • The last three reported values for Free Cash Flow were -$15.1 million (Q4 2025), $168.8 million (Q3 2025), and -$20.3 million (Q2 2025) per Business Quant data.