Septerna (SEPN) Free Cash Flow (2023 - 2026)
Septerna's (SEPN) quarterly Free Cash Flow came in at -$26.5 million in Q1 2026, down 11.55% year-on-year from -$29.9 million in Q1 2025, and down 75.81% quarter-over-quarter from -$15.1 million in Q4 2025.
Septerna (SEPN) Free Cash Flow (2023 - 2026) Analysis & Trends
Septerna's Free Cash Flow history runs 4 years deep, the most recent figure standing at -$26.5 million for Q1 2026.
- On a quarterly basis, Free Cash Flow fell 11.55% year-over-year to -$26.5 million in Q1 2026; TTM through Mar 2026 was $106.9 million, a 241.03% increase from a year earlier, with the FY2025 full-year figure at $109.7 million, up 257.63% from the prior year.
- Free Cash Flow slipped to -$26.5 million in Q1 2026 per SEPN's latest filing, from -$15.1 million in the prior quarter.
- Across five years, Free Cash Flow topped out at $168.8 million in Q3 2025 and bottomed at -$26.5 million in Q1 2026.
- The 4-year median for Free Cash Flow is -$17.4 million (2024), against an average of $359700.0.
- Across the five-year window, Free Cash Flow tumbled 114.93% in 2024 and surged 1070.53% in 2025, its largest moves.
- Year by year, Free Cash Flow stood at -$10.0 million in 2023, then plunged by 114.93% to -$21.6 million in 2024, then surged by 30.21% to -$15.1 million in 2025, then sank by 75.81% to -$26.5 million in 2026.
- Per Business Quant, the three latest SEPN Free Cash Flow figures stand at -$26.5 million (Q1 2026), -$15.1 million (Q4 2025), and $168.8 million (Q3 2025).
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Free Cash Flow (Qtr) |
|---|---|---|---|---|---|
| 1 | Oculis Holding AG | 68,785.72 Bn | 68,785.72 Bn | - | -19.58 Mn |
| 2 | Nanobiotix | 1,895.57 Bn | 1,895.51 Bn | - | - |
| 3 | BeOne Medicines | 471.35 Bn | 466.56 Bn | 1.35 Bn | 158.09 Mn |
| 4 | NuCana | 279.75 Bn | 279.75 Bn | - | -1.53 Mn |
| 5 | Vertex Pharmaceuticals | 120.24 Bn | 113.00 Bn | 2.59 Bn | 1.29 Bn |
| 6 | Regeneron Pharmaceuticals | 67.80 Bn | 59.04 Bn | 3.31 Bn | 848.30 Mn |
| 7 | Belite Bio | 62.51 Bn | 62.51 Bn | - | - |
| 8 | Argenx Se | 57.38 Bn | 57.38 Bn | 1.41 Bn | - |
| 9 | Revolution Medicines | 37.78 Bn | 37.78 Bn | - | -354.95 Mn |
| 10 | Septerna | 1.50 Bn | 1.50 Bn | - | -26.47 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -26.47 Mn |
| Mar 31, 2026 | -26.47 Mn |
| Dec 31, 2025 | -15.05 Mn |
| Dec 31, 2025 | -15.05 Mn |
| Sep 30, 2025 | 168.79 Mn |
| Sep 30, 2025 | 168.79 Mn |
| Jun 30, 2025 | -20.35 Mn |
| Jun 30, 2025 | -20.35 Mn |
| Mar 31, 2025 | -23.73 Mn |
| Mar 31, 2025 | -23.73 Mn |
| Dec 31, 2024 | -21.57 Mn |
| Dec 31, 2024 | -21.57 Mn |
| Sep 30, 2024 | -17.39 Mn |
| Sep 30, 2024 | -17.39 Mn |
| Jun 30, 2024 | -13.14 Mn |
| Jun 30, 2024 | -13.14 Mn |
| Mar 31, 2024 | -17.48 Mn |
| Mar 31, 2024 | -17.48 Mn |
| Dec 31, 2023 | -10.04 Mn |
| Dec 31, 2023 | -10.04 Mn |