Septerna (SEPN) FCF Margin (2023 - 2026)
Septerna (SEPN) recorded quarterly FCF Margin of 99.87% in Q1 2026, down 60.01% quarter-over-quarter from 62.41% in Q4 2025, and up 1073347.0% on a YoY basis from N/an in Q1 2025.
Septerna (SEPN) FCF Margin (2023 - 2026) Analysis & Trends
Septerna's FCF Margin history runs 4 years deep, the most recent figure standing at 99.87% for Q1 2026.
- In Q1 2026, FCF Margin rose 1073347.0% year-over-year to 99.87%; the TTM figure through Mar 2026 stood at 148.04% (up 790884.0% YoY), while the FY2025 annual figure was 238.67%, up 671058.0% from the prior year.
- FCF Margin was 99.87% for Q1 2026 at Septerna, down from 62.41% in the prior quarter.
- In the past five years, FCF Margin ranged from a high of 785.27% in Q3 2025 to a low of 17096.64% in Q2 2025.
- Historically, FCF Margin has averaged 6493.13% across 4 years, with a median of 7008.85% in 2023.
- The sharpest annual moves came in 2025 and 2026: FCF Margin sank 1354637 bps in 2025, then surged 1073347 bps in 2026.
- A 4-year view of FCF Margin shows it stood at 8505.08% in 2023, then slipped by 20 bps to 10174.53% in 2024, then soared by 99 bps to 62.41% in 2025, then plunged by 60 bps to 99.87% in 2026.
- The last three FCF Margin figures came in at 99.87% (Q1 2026), 62.41% (Q4 2025), and 785.27% (Q3 2025), per Business Quant data.
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Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | FCF Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Alterity Therapeutics | 719,706.53 Bn | 719,706.50 Bn | - | - |
| 2 | Belite Bio | 55,800.00 Bn | 55,800.00 Bn | - | - |
| 3 | Quantum Biopharma | 18,182.30 Bn | 18,182.29 Bn | - | - |
| 4 | Legend Biotech | 3,154.00 Bn | 3,153.71 Bn | 242.10 Mn | -3.98% |
| 5 | Akari Therapeutics | 1,844.30 Bn | 1,844.29 Bn | - | - |
| 6 | Evaxion A | 1,567.96 Bn | 1,567.94 Bn | - | - |
| 7 | Psyence Biomedical | 251.43 Bn | 251.42 Bn | - | - |
| 8 | Vertex Pharmaceuticals | 112.56 Bn | 105.31 Bn | 2.59 Bn | 43.35% |
| 9 | Abivax | 94.37 Bn | 94.37 Bn | - | - |
| 10 | Septerna | 1.37 Bn | 1.37 Bn | - | -99.87% |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -99.87% |
| Dec 31, 2025 | -62.41% |
| Sep 30, 2025 | 785.27% |
| Jun 30, 2025 | -17,096.64% |
| Mar 31, 2025 | -10,833.33% |
| Dec 31, 2024 | -10,174.53% |
| Sep 30, 2024 | -9,881.82% |
| Jun 30, 2024 | -3,550.27% |
| Mar 31, 2024 | -5,512.62% |
| Dec 31, 2023 | -8,505.08% |