Septerna (SEPN) FCF Margin (2023 - 2026)
Septerna's (SEPN) quarterly FCF Margin came in at 99.87% in Q1 2026, up 1073347.0% year-on-year from N/an in Q1 2025, and down 60.01% quarter-over-quarter from 62.41% in Q4 2025.
Septerna (SEPN) FCF Margin (2023 - 2026) Analysis & Trends
Septerna's FCF Margin history runs 4 years deep, the most recent figure standing at 99.87% for Q1 2026.
- On a quarterly basis, FCF Margin rose 1073347.0% year-over-year to 99.87% in Q1 2026; TTM through Mar 2026 was 148.04%, a 790884.0% increase from a year earlier, with the FY2025 full-year figure at 238.67%, up 671058.0% from the prior year.
- FCF Margin eased to 99.87% in Q1 2026 per SEPN's latest filing, from 62.41% in the prior quarter.
- Across five years, FCF Margin topped out at 785.27% in Q3 2025 and bottomed at 17096.64% in Q2 2025.
- The 4-year median for FCF Margin is 7008.85% (2023), against an average of 6493.13%.
- Across the five-year window, FCF Margin sank 1354637 bps in 2025 and jumped 1073347 bps in 2026, its largest moves.
- Year by year, FCF Margin stood at 8505.08% in 2023, then slipped by 20 bps to 10174.53% in 2024, then soared by 99 bps to 62.41% in 2025, then slumped by 60 bps to 99.87% in 2026.
- Per Business Quant, the three latest SEPN FCF Margin figures stand at 99.87% (Q1 2026), 62.41% (Q4 2025), and 785.27% (Q3 2025).
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Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | FCF Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Oculis Holding AG | 68,785.72 Bn | 68,785.72 Bn | - | - |
| 2 | Nanobiotix | 1,895.57 Bn | 1,895.51 Bn | - | - |
| 3 | BeOne Medicines | 471.35 Bn | 466.56 Bn | 1.35 Bn | 10.45% |
| 4 | NuCana | 279.75 Bn | 279.75 Bn | - | - |
| 5 | Vertex Pharmaceuticals | 120.24 Bn | 113.00 Bn | 2.59 Bn | 43.35% |
| 6 | Regeneron Pharmaceuticals | 67.80 Bn | 59.04 Bn | 3.31 Bn | 23.53% |
| 7 | Belite Bio | 62.51 Bn | 62.51 Bn | - | - |
| 8 | Argenx Se | 57.38 Bn | 57.38 Bn | 1.41 Bn | - |
| 9 | Revolution Medicines | 37.78 Bn | 37.78 Bn | - | - |
| 10 | Septerna | 1.50 Bn | 1.50 Bn | - | -99.87% |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -99.87% |
| Dec 31, 2025 | -62.41% |
| Sep 30, 2025 | 785.27% |
| Jun 30, 2025 | -17,096.64% |
| Mar 31, 2025 | -10,833.33% |
| Dec 31, 2024 | -10,174.53% |
| Sep 30, 2024 | -9,881.82% |
| Jun 30, 2024 | -3,550.27% |
| Mar 31, 2024 | -5,512.62% |
| Dec 31, 2023 | -8,505.08% |