Septerna (SEPN) FCF Margin (2023 - 2026)
Septerna's quarterly FCF Margin came in at 99.87% in Q1 2026, up 1073347.0% year-on-year from N/an in Q1 2025, and down 60.01% quarter-over-quarter from 62.41% in Q4 2025.
Septerna has reported FCF Margin for 4 years, with the latest figure at 99.87% in Q1 2026.
- For the quarter ending Q1 2026, FCF Margin rose 1073347.0% year-over-year to 99.87%; the trailing twelve-month figure through Mar 2026 stood at 148.04% (up 790884.0% YoY), and the FY2025 full-year result was 238.67%, up 671058.0% from the prior year.
- FCF Margin for Q1 2026 stood at 99.87%, down from 62.41% in the prior quarter.
- The five-year high for FCF Margin was 785.27% in Q3 2025, with the low at 17096.64% in Q2 2025.
- Average FCF Margin over 4 years is 6493.13%, with a median of 7008.85% recorded in 2023.
- Year-over-year, FCF Margin sank 1354637 bps in 2025 and jumped 1073347 bps in 2026.
- Tracing SEPN's FCF Margin over 4 years: stood at 8505.08% in 2023, then dropped by 20 bps to 10174.53% in 2024, then jumped by 99 bps to 62.41% in 2025, then tumbled by 60 bps to 99.87% in 2026.
- The last three FCF Margin figures came in at 99.87% (Q1 2026), 62.41% (Q4 2025), and 785.27% (Q3 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | FCF Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Quantum Biopharma | 961,148.99 Bn | 961,148.98 Bn | - | - |
| 2 | Alterity Therapeutics | 744,933.29 Bn | 744,933.26 Bn | - | - |
| 3 | Legend Biotech | 2,540.00 Bn | 2,539.71 Bn | 242.10 Mn | -3.98% |
| 4 | Nanobiotix | 2,199.85 Bn | 2,199.78 Bn | - | - |
| 5 | Akari Therapeutics | 1,635.88 Bn | 1,635.88 Bn | - | - |
| 6 | Vertex Pharmaceuticals | 111.32 Bn | 104.07 Bn | 2.59 Bn | 43.35% |
| 7 | Evaxion A | 62.56 Bn | 62.54 Bn | - | - |
| 8 | Regeneron Pharmaceuticals | 62.55 Bn | 53.79 Bn | 3.31 Bn | 23.53% |
| 9 | Alnylam Pharmaceuticals | 39.57 Bn | 36.56 Bn | 959.66 Mn | 4.17% |
| 10 | Septerna | 1.34 Bn | 1.34 Bn | - | -99.87% |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -99.87% |
| Dec 31, 2025 | -62.41% |
| Sep 30, 2025 | 785.27% |
| Jun 30, 2025 | -17,096.64% |
| Mar 31, 2025 | -10,833.33% |
| Dec 31, 2024 | -10,174.53% |
| Sep 30, 2024 | -9,881.82% |
| Jun 30, 2024 | -3,550.27% |
| Mar 31, 2024 | -5,512.62% |
| Dec 31, 2023 | -8,505.08% |