Septerna (SEPN) FCF Margin (2023 - 2026)
Septerna (SEPN) posted FCF Margin of -82.92% for Q2 2026, up 17013.71 percentage points from -17096.64% a year earlier and up 16.86 percentage points from the prior quarter.
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Analysis
Septerna (SEPN) FCF Margin (2023 - 2026) Analysis & Trends
For the trailing twelve months through Jun 30, 2026, FCF Margin at Septerna was 106.29%, up 11543.20 percentage points year-over-year; for FY2025, it came in at 238.67%, up 6710.58 percentage points from FY2024.
- In prior years, Septerna's FCF Margin was -6471.91% in FY2024 (+21078.42 pp) and -27550.33% in FY2023.
- Quarterly FCF Margin has run from a low of -17096.64% in Q2 2025 to a high of 785.27% in Q3 2025 over five years.
- On a year-over-year basis, FCF Margin has increased in each of the last four quarters, with an average year-over-year change of +3998.56 percentage points over the last seven quarters.
- According to Business Quant data, FCF Margin for the three prior quarters was -99.78% (Q1 2026), -62.41% (Q4 2025) and 785.27% (Q3 2025).
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | FCF Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Johnson & Johnson | 655.56 Bn | 574.09 Bn | 17.26 Bn | 28.82% |
| 2 | AbbVie | 470.94 Bn | 444.10 Bn | 12.70 Bn | 18.33% |
| 3 | Merck | 367.14 Bn | 321.57 Bn | 12.21 Bn | 26.96% |
| 4 | Novartis Ag | 280.33 Bn | 236.20 Bn | 11.24 Bn | 43.05% |
| 5 | Astrazeneca | 257.78 Bn | 231.34 Bn | 12.86 Bn | 34.72% |
| 6 | Amgen | 226.04 Bn | 181.44 Bn | 7.24 Bn | 34.70% |
| 7 | Gilead Sciences | 188.89 Bn | 163.01 Bn | 6.22 Bn | 44.00% |
| 8 | Pfizer | 163.75 Bn | 110.70 Bn | 10.94 Bn | 2.01% |
| 9 | Vertex Pharmaceuticals | 133.68 Bn | 105.69 Bn | 2.84 Bn | 30.39% |
| 10 | Septerna | 1.81 Bn | 1.81 Bn | - | -82.92% |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | -82.92% |
| Mar 31, 2026 | -99.78% |
| Dec 31, 2025 | -62.41% |
| Sep 30, 2025 | 785.27% |
| Jun 30, 2025 | -17,096.64% |
| Mar 31, 2025 | -10,833.33% |
| Dec 31, 2024 | -10,174.53% |
| Sep 30, 2024 | -9,881.82% |
| Jun 30, 2024 | -3,550.27% |
| Mar 31, 2024 | -5,512.62% |
| Dec 31, 2023 | -8,505.08% |
API Access
Septerna FCF Margin API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=fcf-margin&ticker=SEPN&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "fcf-margin", "ticker": "SEPN", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=fcf-margin&ticker=SEPN&period=max&api_key=YOUR_API_KEY");
const data = await res.json();