Septerna (SEPN) Enterprise Value (2023 - 2026)
Septerna's quarterly Enterprise Value came in at -$347.4 million in Q1 2026, down 3.39% year-on-year from -$359.6 million in Q1 2025, and up 11.17% quarter-over-quarter from -$391.1 million in Q4 2025.
Septerna has reported Enterprise Value for 4 years, with the latest figure at -$347.4 million in Q1 2026.
- For the quarter ending Q1 2026, Enterprise Value fell 3.39% year-over-year to -$347.4 million; the trailing twelve-month figure through Mar 2026 stood at -$347.4 million (down 3.39% YoY), and the FY2025 full-year result was -$391.1 million, down 11.45% from the prior year.
- Enterprise Value for Q1 2026 stood at -$347.4 million, up from -$391.1 million in the prior quarter.
- The five-year high for Enterprise Value was -$81.3 million in Q1 2024, with the low at -$474.3 million in Q3 2025.
- Average Enterprise Value over 4 years is -$250.6 million, with a median of -$326.6 million recorded in 2025.
- Year-over-year, Enterprise Value tumbled 313.09% in 2025 and declined 3.39% in 2026.
- Tracing SEPN's Enterprise Value over 4 years: stood at -$88.5 million in 2023, then slumped by 296.6% to -$350.9 million in 2024, then fell by 11.45% to -$391.1 million in 2025, then advanced by 11.17% to -$347.4 million in 2026.
- The last three Enterprise Value figures came in at -$347.4 million (Q1 2026), -$391.1 million (Q4 2025), and -$474.3 million (Q3 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Enterprise Value (Qtr) |
|---|---|---|---|---|---|
| 1 | Quantum Biopharma | 961,148.99 Bn | 961,148.98 Bn | - | -2.32 Mn |
| 2 | Alterity Therapeutics | 744,933.29 Bn | 744,933.26 Bn | - | -32.30 Mn |
| 3 | Legend Biotech | 2,540.00 Bn | 2,539.71 Bn | 242.10 Mn | -286.70 Mn |
| 4 | Nanobiotix | 2,199.85 Bn | 2,199.78 Bn | - | -61.46 Mn |
| 5 | Akari Therapeutics | 1,635.88 Bn | 1,635.88 Bn | - | -2.77 Mn |
| 6 | Vertex Pharmaceuticals | 111.32 Bn | 104.07 Bn | 2.59 Bn | -7.25 Bn |
| 7 | Evaxion A | 62.56 Bn | 62.54 Bn | - | -18.44 Mn |
| 8 | Regeneron Pharmaceuticals | 62.55 Bn | 53.79 Bn | 3.31 Bn | -8.75 Bn |
| 9 | Alnylam Pharmaceuticals | 39.57 Bn | 36.56 Bn | 959.66 Mn | -3.01 Bn |
| 10 | Septerna | 1.34 Bn | 1.34 Bn | - | -347.40 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -347.40 Mn |
| Dec 31, 2025 | -391.09 Mn |
| Sep 30, 2025 | -474.35 Mn |
| Jun 30, 2025 | -326.56 Mn |
| Mar 31, 2025 | -336.01 Mn |
| Dec 31, 2024 | -350.92 Mn |
| Sep 30, 2024 | -130.53 Mn |
| Jun 30, 2024 | -131.17 Mn |
| Mar 31, 2024 | -81.34 Mn |
| Dec 31, 2023 | -88.48 Mn |
| Sep 30, 2023 | -98.52 Mn |