Septerna (SEPN) Enterprise Value (2023 - 2026)

Septerna's Enterprise Value history runs 4 years deep, the most recent figure standing at -$347.4 million for Q1 2026.

• In Q1 2026, Enterprise Value fell 3.39% year-over-year to -$347.4 million; the TTM figure through Mar 2026 stood at -$347.4 million (down 3.39% YoY), while the FY2025 annual figure was -$391.1 million, down 11.45% from the prior year.
• Enterprise Value was -$347.4 million for Q1 2026 at Septerna, up from -$391.1 million in the prior quarter.
• In the past five years, Enterprise Value ranged from a high of -$81.3 million in Q1 2024 to a low of -$474.3 million in Q3 2025.
• Historically, Enterprise Value has averaged -$250.6 million across 4 years, with a median of -$326.6 million in 2025.
• The sharpest annual moves came in 2025 and 2026: Enterprise Value tumbled 313.09% in 2025, then slipped 3.39% in 2026.
• A 4-year view of Enterprise Value shows it stood at -$88.5 million in 2023, then tumbled by 296.6% to -$350.9 million in 2024, then declined by 11.45% to -$391.1 million in 2025, then gained by 11.17% to -$347.4 million in 2026.
• The last three Enterprise Value figures came in at -$347.4 million (Q1 2026), -$391.1 million (Q4 2025), and -$474.3 million (Q3 2025), per Business Quant data.