Septerna (SEPN) Enterprise Value (2023 - 2025)

Septerna has reported Enterprise Value over the past 3 years, most recently at -$391.1 million for Q4 2025.

  • Quarterly results put Enterprise Value at -$391.1 million for Q4 2025, down 11.45% from a year ago — trailing twelve months through Dec 2025 was -$391.1 million (down 11.45% YoY), and the annual figure for FY2025 was -$391.1 million, down 11.45%.
  • Enterprise Value for Q4 2025 was -$391.1 million at Septerna, up from -$474.3 million in the prior quarter.
  • Over the last five years, Enterprise Value for SEPN hit a ceiling of -$81.3 million in Q1 2024 and a floor of -$474.3 million in Q3 2025.
  • Median Enterprise Value over the past 3 years was -$228.9 million (2024), compared with a mean of -$240.9 million.
  • Peak annual rise in Enterprise Value hit 11.45% in 2025, while the deepest fall reached 313.09% in 2025.
  • Septerna's Enterprise Value stood at -$88.5 million in 2023, then tumbled by 296.6% to -$350.9 million in 2024, then fell by 11.45% to -$391.1 million in 2025.
  • The last three reported values for Enterprise Value were -$391.1 million (Q4 2025), -$474.3 million (Q3 2025), and -$326.6 million (Q2 2025) per Business Quant data.