Septerna (SEPN) Enterprise Value (2023 - 2026)
Septerna's (SEPN) quarterly Enterprise Value came in at -$347.4 million in Q1 2026, down 3.39% year-on-year from -$359.6 million in Q1 2025, and up 11.17% quarter-over-quarter from -$391.1 million in Q4 2025.
Septerna (SEPN) Enterprise Value (2023 - 2026) Analysis & Trends
Septerna's Enterprise Value history runs 4 years deep, the most recent figure standing at -$347.4 million for Q1 2026.
- On a quarterly basis, Enterprise Value fell 3.39% year-over-year to -$347.4 million in Q1 2026; TTM through Mar 2026 was -$347.4 million, a 3.39% decrease from a year earlier, with the FY2025 full-year figure at -$391.1 million, down 11.45% from the prior year.
- Enterprise Value advanced to -$347.4 million in Q1 2026 per SEPN's latest filing, from -$391.1 million in the prior quarter.
- Across five years, Enterprise Value topped out at -$81.3 million in Q1 2024 and bottomed at -$474.3 million in Q3 2025.
- The 4-year median for Enterprise Value is -$326.6 million (2025), against an average of -$250.6 million.
- Across the five-year window, Enterprise Value tumbled 313.09% in 2025 and declined 3.39% in 2026, its largest moves.
- Year by year, Enterprise Value stood at -$88.5 million in 2023, then sank by 296.6% to -$350.9 million in 2024, then declined by 11.45% to -$391.1 million in 2025, then gained by 11.17% to -$347.4 million in 2026.
- Per Business Quant, the three latest SEPN Enterprise Value figures stand at -$347.4 million (Q1 2026), -$391.1 million (Q4 2025), and -$474.3 million (Q3 2025).
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Enterprise Value (Qtr) |
|---|---|---|---|---|---|
| 1 | Oculis Holding AG | 68,785.72 Bn | 68,785.72 Bn | - | -283.54 Mn |
| 2 | Nanobiotix | 1,895.57 Bn | 1,895.51 Bn | - | -61.40 Mn |
| 3 | BeOne Medicines | 471.35 Bn | 466.56 Bn | 1.35 Bn | -4.79 Bn |
| 4 | NuCana | 279.75 Bn | 279.75 Bn | - | -32.26 Mn |
| 5 | Vertex Pharmaceuticals | 120.24 Bn | 113.00 Bn | 2.59 Bn | -7.25 Bn |
| 6 | Regeneron Pharmaceuticals | 67.80 Bn | 59.04 Bn | 3.31 Bn | -8.75 Bn |
| 7 | Belite Bio | 62.51 Bn | 62.51 Bn | - | - |
| 8 | Argenx Se | 57.38 Bn | 57.38 Bn | 1.41 Bn | -5.18 Bn |
| 9 | Revolution Medicines | 37.78 Bn | 37.78 Bn | - | -1.91 Bn |
| 10 | Septerna | 1.50 Bn | 1.50 Bn | - | -347.40 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -347.40 Mn |
| Dec 31, 2025 | -391.09 Mn |
| Sep 30, 2025 | -474.35 Mn |
| Jun 30, 2025 | -326.56 Mn |
| Mar 31, 2025 | -336.01 Mn |
| Dec 31, 2024 | -350.92 Mn |
| Sep 30, 2024 | -130.53 Mn |
| Jun 30, 2024 | -131.17 Mn |
| Mar 31, 2024 | -81.34 Mn |
| Dec 31, 2023 | -88.48 Mn |
| Sep 30, 2023 | -98.52 Mn |